Protein: KDM4A
Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A)

Gene: KDM4A
Organism: Homo sapiens
Interactions: 86
UniProt ID: O75164

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001650 - fibrillar center
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005721 - pericentric heterochromatin

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

256927

KDM4B
Lysine-specific demethylase 4B

2

15

High-throughput

0.789

High

256961

H31
Histone H3.1

4

20

Small-scale

0.700

High

256997

KDM5B
Lysine-specific demethylase 5B

1

12

High-throughput

0.691

High

256958

H4
Histone H4

3

6

Small-scale

0.671

High

256971

STK11
Serine/threonine-protein kinase STK11

2

1

High-throughput

0.628

High

256986

ZN414
Zinc finger protein 414

2

2

High-throughput

0.628

High

256924

NCOR1
Nuclear receptor corepressor 1

2

6

Small-scale

0.624

High

256923

KDM4A
Lysine-specific demethylase 4A

1

15

Small-scale

0.618

High

256980

CHD5
Chromodomain-helicase-DNA-binding protein 5

1

7

Small-scale

0.618

High

256994

KDM4C
Lysine-specific demethylase 4C

1

15

Small-scale

0.618

High

256973

H31T
Histone H3.1t

1

20

Small-scale

0.586

High

256977

FBX22
F-box only protein 22

2

3

Small-scale

0.584

High

99460

F5GX28
[histone H3]-trimethyl-L-lysine(9) demethylase

1

15

High-throughput

0.575

High

134715

CCL22
C-C motif chemokine 22

2

1

High-throughput

0.574

High

256930

P53
Cellular tumor antigen p53

2

5

Small-scale

0.571

High

256963

H33
Histone H3.3

2

20

Small-scale

0.571

High

256970

CUL1
Cullin-1

2

3

Small-scale

0.571

High

256938

ERG
Transcriptional regulator ERG

1

4

Small-scale

0.561

High

256932

RB
Retinoblastoma-associated protein

1

4

Small-scale

0.552

High

256983

RSPH1
Radial spoke head 1 homolog

1

1

High-throughput

0.541

High

256926

PLPHP
Pyridoxal phosphate homeostasis protein

1

1

High-throughput

0.536

High

256929

CYTA
Cystatin-A

1

1

High-throughput

0.536

High

256934

S10A9
Protein S100-A9

1

2

High-throughput

0.536

High

256936

H2AZ
Histone H2A.Z

1

4

High-throughput

0.536

High

256957

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.536

High

256959

TRA2B
Transformer-2 protein homolog beta

1

4

High-throughput

0.536

High

256960

TBA1B
Tubulin alpha-1B chain

1

3

High-throughput

0.536

High

256966

SRSF1
Serine/arginine-rich splicing factor 1

1

1

High-throughput

0.536

High

256967

STK4
Serine/threonine-protein kinase 4

1

1

High-throughput

0.536

High

256968

CAF1B
Chromatin assembly factor 1 subunit B

1

6

High-throughput

0.536

High

257000

CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

0.536

High

256978

WDR48
WD repeat-containing protein 48

1

8

High-throughput

0.515

High

159522

ML12B
Myosin regulatory light chain 12B

1

0

High-throughput

0.513

High

256928

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.513

High

256931

ARGI1
Arginase-1

1

0

High-throughput

0.513

High

256940

SPR1B
Cornifin-B

1

0

High-throughput

0.513

High

256943

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

0

High-throughput

0.513

High

256981

AF1L1
Actin filament-associated protein 1-like 1

1

0

High-throughput

0.513

High

256982

ABHD5
1-acylglycerol-3-phosphate O-acyltransferase ABHD5

1

0

High-throughput

0.513

High

256992

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.513

High

256925

RNF8
E3 ubiquitin-protein ligase RNF8

1

7

Small-scale

0.501

High

256979

POC1B
POC1 centriolar protein homolog B

1

4

High-throughput

0.489

High

256989

CCL19
C-C motif chemokine 19

1

1

High-throughput

0.489

High

256941

MCM3
DNA replication licensing factor MCM3

1

8

Small-scale

0.484

High

256947

MCM7
DNA replication licensing factor MCM7

1

7

Small-scale

0.484

High

256976

RN168
E3 ubiquitin-protein ligase RNF168

1

0

Small-scale

0.480

High

177151

HDAC3
Histone deacetylase 3

1

13

Small-scale

0.479

High

226036

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

256937

ANDR
Androgen receptor

1

18

Small-scale

0.479

High

256952

WASP
Actin nucleation-promoting factor WAS

1

1

Small-scale

0.479

High

256953

PPIC
Peptidyl-prolyl cis-trans isomerase C

1

2

Small-scale

0.479

High

256955

ZN131
Zinc finger protein 131

1

5

High-throughput

0.479

High

256956

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

Small-scale

0.479

High

256969

HDAC1
Histone deacetylase 1

1

14

Small-scale

0.479

High

256974

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.479

High

256990

CDC6
Cell division control protein 6 homolog

1

5

Small-scale

0.479

High

256991

ASCL2
Achaete-scute homolog 2

1

4

Small-scale

0.479

High

256998

FBXL4
F-box/LRR-repeat protein 4

1

2

Small-scale

0.479

High

256996

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.457

High

256999

TNIK
TRAF2 and NCK-interacting protein kinase

1

2

High-throughput

0.457

High

256935

DPOLA
DNA polymerase alpha catalytic subunit

1

3

Small-scale

0.445

High

256942

DPOD1
DNA polymerase delta catalytic subunit

1

3

Small-scale

0.445

High

256945

MCM4
DNA replication licensing factor MCM4

1

7

Small-scale

0.445

High

256946

MCM5
DNA replication licensing factor MCM5

1

8

Small-scale

0.445

High

256948

RFC4
Replication factor C subunit 4

1

6

Small-scale

0.445

High

256949

RFC2
Replication factor C subunit 2

1

6

Small-scale

0.445

High

256951

RFC5
Replication factor C subunit 5

1

6

Small-scale

0.445

High

256954

MCM2
DNA replication licensing factor MCM2

1

7

Small-scale

0.445

High

256965

DPOE1
DNA polymerase epsilon catalytic subunit A

1

3

Small-scale

0.445

High

256972

DDB1
DNA damage-binding protein 1

1

2

Small-scale

0.445

High

256975

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

Small-scale

0.445

High

256984

RENT1
Regulator of nonsense transcripts 1

1

1

Small-scale

0.445

High

256985

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

Small-scale

0.445

High

256988

WRIP1
ATPase WRNIP1

1

9

Small-scale

0.445

High

257001

TRRAP
Transformation/transcription domain-associated protein

1

1

Small-scale

0.445

High

256993

DDX24
ATP-dependent RNA helicase DDX24

1

4

High-throughput

0.437

High

256933

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.426

High

256944

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial

1

0

Small-scale

0.426

High

256964

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

Small-scale

0.426

High

256995

CYBP
Calcyclin-binding protein

1

0

Small-scale

0.426

High

56579

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.407

High

256962

DCD
Dermcidin

1

0

High-throughput

0.279

Low

256939

RHOQ
Rho-related GTP-binding protein RhoQ

1

0

Small-scale

0.249

Low

256950

GPV
Platelet glycoprotein V

1

0

Small-scale

0.249

Low

256987

PANX2
Pannexin-2

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024