Protein: PHLB2
Pleckstrin homology-like domain family B member 2 (Protein LL5-beta)

Gene: PHLB2, PHLDB2
Organism: Homo sapiens
Interactions: 137
UniProt ID: Q86SQ0

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0010470 - regulation of gastrulation
GO:0010717 - regulation of epithelial to mesenchymal transition

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

350299

RASK
GTPase KRas

2

20

High-throughput

0.754

High

915794

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

683501

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.722

High

927232

1433Z
14-3-3 protein zeta/delta

5

20

High-throughput

0.718

High

904789

1433G
14-3-3 protein gamma

4

20

High-throughput

0.699

High

647058

1433T
14-3-3 protein theta

4

20

High-throughput

0.697

High

557179

PGFRA
Platelet-derived growth factor receptor alpha

1

8

High-throughput

0.691

High

1197833

RGAP1
Rac GTPase-activating protein 1

1

15

High-throughput

0.691

High

982217

1433F
14-3-3 protein eta

3

20

High-throughput

0.667

High

909748

1433E
14-3-3 protein epsilon

2

7

High-throughput

0.635

High

166581

DCLK1
Serine/threonine-protein kinase DCLK1

1

9

High-throughput

0.618

High

253375

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

14

High-throughput

0.618

High

349435

RASH
GTPase HRas

1

17

High-throughput

0.618

High

433861

LYN
Tyrosine-protein kinase Lyn

1

11

High-throughput

0.618

High

436377

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

545470

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

876430

AFAD
Afadin

1

20

High-throughput

0.618

High

892457

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

900641

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

925400

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

960386

CDK16
Cyclin-dependent kinase 16

1

18

High-throughput

0.618

High

997179

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

15

High-throughput

0.618

High

1022415

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

14

High-throughput

0.618

High

1066331

KIF14
Kinesin-like protein KIF14

1

20

High-throughput

0.618

High

1136520

SPD2A
SH3 and PX domain-containing protein 2A

1

6

High-throughput

0.618

High

1146570

A16L1
Autophagy-related protein 16-1

1

18

High-throughput

0.618

High

1197808

KSR1
Kinase suppressor of Ras 1

1

15

High-throughput

0.618

High

1197822

SH3K1
SH3 domain-containing kinase-binding protein 1

1

17

High-throughput

0.618

High

1197836

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1197837

ECT2
Protein ECT2

1

20

High-throughput

0.618

High

1197840

ANLN
Anillin

1

10

High-throughput

0.618

High

1197841

LATS2
Serine/threonine-protein kinase LATS2

1

20

High-throughput

0.618

High

1197856

FBW1A
F-box/WD repeat-containing protein 1A

1

17

High-throughput

0.618

High

1197819

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

2

14

High-throughput

0.614

High

504323

HSP7C
Heat shock cognate 71 kDa protein

2

10

High-throughput

0.611

High

598203

FLNA
Filamin-A

2

19

Small-scale

0.611

High

969816

KIF23
Kinesin-like protein KIF23

2

20

High-throughput

0.611

High

1197831

RTKN
Rhotekin

1

0

High-throughput

0.586

High

833762

CLK1
Dual specificity protein kinase CLK1

1

20

High-throughput

0.579

High

338640

EGFR
Epidermal growth factor receptor

1

8

High-throughput

0.575

High

1052897

FLNC
Filamin-C

1

20

Small-scale

0.561

High

347195

MYC
Myc proto-oncogene protein

2

13

High-throughput

0.558

High

684165

1433S
14-3-3 protein sigma

1

20

High-throughput

0.554

High

230889

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

13

High-throughput

0.553

High

1136460

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

7

High-throughput

0.553

High

1197839

KI13B
Kinesin-like protein KIF13B

1

17

High-throughput

0.553

High

1197855

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

7

High-throughput

0.553

High

117748

MYO1C
Unconventional myosin-Ic

1

16

High-throughput

0.536

High

151063

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

15

High-throughput

0.536

High

272620

OFD1
Centriole and centriolar satellite protein OFD1

1

19

High-throughput

0.536

High

364948

FRIL
Ferritin light chain

1

2

High-throughput

0.536

High

813090

CAZA2
F-actin-capping protein subunit alpha-2

1

9

High-throughput

0.536

High

928360

DYL1
Dynein light chain 1, cytoplasmic

1

6

High-throughput

0.536

High

984620

CALD1
Caldesmon

1

19

High-throughput

0.536

High

1197810

SYNPO
Synaptopodin

1

15

High-throughput

0.536

High

1197818

MY18A
Unconventional myosin-XVIIIa

1

18

High-throughput

0.536

High

1197823

MYO19
Unconventional myosin-XIX

1

18

High-throughput

0.536

High

1197860

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

1

High-throughput

0.536

High

1197816

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.517

High

1197827

TESK2
Dual specificity testis-specific protein kinase 2

1

0

High-throughput

0.517

High

1197807

PATL1
Protein PAT1 homolog 1

1

6

High-throughput

0.515

High

275042

RENR
Renin receptor

1

0

High-throughput

0.513

High

1101506

KIF7
Kinesin-like protein KIF7

1

8

High-throughput

0.489

High

1197809

TXLNB
Beta-taxilin

1

18

High-throughput

0.489

High

1197859

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

High-throughput

0.489

High

155017

NDC80
Kinetochore protein NDC80 homolog

1

17

High-throughput

0.479

High

196472

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

7

High-throughput

0.479

High

255893

OBSL1
Obscurin-like protein 1

1

14

High-throughput

0.479

High

264345

GGYF1
GRB10-interacting GYF protein 1

1

12

High-throughput

0.479

High

279615

FLOT1
Flotillin-1

1

7

High-throughput

0.479

High

301905

TRI37
E3 ubiquitin-protein ligase TRIM37

1

20

High-throughput

0.479

High

522037

CADH1
Cadherin-1

1

8

High-throughput

0.479

High

529351

CFTR
Cystic fibrosis transmembrane conductance regulator

1

14

High-throughput

0.479

High

567140

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

598493

NF1
Neurofibromin

1

11

High-throughput

0.479

High

673494

MPIP2
M-phase inducer phosphatase 2

1

3

High-throughput

0.479

High

673599

MPIP3
M-phase inducer phosphatase 3

1

3

High-throughput

0.479

High

717190

CTNB1
Catenin beta-1

1

10

High-throughput

0.479

High

813585

CAPZB
F-actin-capping protein subunit beta

1

5

High-throughput

0.479

High

880770

HDAC4
Histone deacetylase 4

1

20

High-throughput

0.479

High

1021424

ANK3
Ankyrin-3

1

12

High-throughput

0.479

High

1030329

G3BP1
Ras GTPase-activating protein-binding protein 1

1

6

High-throughput

0.479

High

1061482

CUL7
Cullin-7

1

8

High-throughput

0.479

High

1084074

OCLN
Occludin

1

2

High-throughput

0.479

High

1139610

DEN4C
DENN domain-containing protein 4C

1

3

High-throughput

0.479

High

1145812

CP135
Centrosomal protein of 135 kDa

1

17

High-throughput

0.479

High

1167913

GGYF2
GRB10-interacting GYF protein 2

1

19

High-throughput

0.479

High

1173126

SYDE1
Rho GTPase-activating protein SYDE1

1

14

High-throughput

0.479

High

1190166

CLAP1
CLIP-associating protein 1

1

8

Small-scale

0.479

High

1197811

FBXW8
F-box/WD repeat-containing protein 8

1

18

High-throughput

0.479

High

1197813

F110B
Protein FAM110B

1

2

High-throughput

0.479

High

1197814

DEN1A
DENN domain-containing protein 1A

1

3

High-throughput

0.479

High

1197815

PARD3
Partitioning defective 3 homolog

1

15

High-throughput

0.479

High

1197825

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

16

High-throughput

0.479

High

1197829

F110A
Protein FAM110A

1

2

High-throughput

0.479

High

1197830

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.479

High

1197832

CP250
Centrosome-associated protein CEP250

1

19

High-throughput

0.479

High

1197834

CCDC8
Coiled-coil domain-containing protein 8

1

7

High-throughput

0.479

High

1197835

VP33B
Vacuolar protein sorting-associated protein 33B

1

1

High-throughput

0.479

High

1197842

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

5

High-throughput

0.479

High

1197844

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

1

High-throughput

0.479

High

1197845

CING
Cingulin

1

18

High-throughput

0.479

High

1197846

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1197847

LIMA1
LIM domain and actin-binding protein 1

1

9

High-throughput

0.479

High

1197848

NGAP
Ras GTPase-activating protein nGAP

1

11

High-throughput

0.479

High

1197850

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

10

High-throughput

0.479

High

1197851

BRPF3
Bromodomain and PHD finger-containing protein 3

1

7

High-throughput

0.479

High

1197852

ZBT21
Zinc finger and BTB domain-containing protein 21

1

2

High-throughput

0.479

High

1197854

MYO6
Unconventional myosin-VI

1

18

High-throughput

0.479

High

1197858

KCTD3
BTB/POZ domain-containing protein KCTD3

1

4

High-throughput

0.479

High

237254

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

316262

NADK
NAD kinase

1

0

High-throughput

0.458

High

1197824

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.458

High

1197828

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

1197857

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

56654

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.445

High

484157

CALM3
Calmodulin-3

1

6

High-throughput

0.445

High

968176

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

5

High-throughput

0.445

High

233527

NUPR1
Nuclear protein 1

1

4

High-throughput

0.437

High

308841

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

1060560

ZN638
Zinc finger protein 638

1

7

High-throughput

0.437

High

1081302

E2F4
Transcription factor E2F4

1

1

High-throughput

0.437

High

1148992

AN34A
Ankyrin repeat domain-containing protein 34A

1

17

High-throughput

0.437

High

1170612

TRI67
Tripartite motif-containing protein 67

1

19

High-throughput

0.437

High

1172659

CE128
Centrosomal protein of 128 kDa

1

19

High-throughput

0.437

High

1182919

SPT6H
Transcription elongation factor SPT6

1

8

High-throughput

0.437

High

1185055

DET1
DET1 homolog

1

1

High-throughput

0.437

High

1197817

SRS12
Serine/arginine-rich splicing factor 12

1

15

High-throughput

0.437

High

1197820

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1197821

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

High-throughput

0.437

High

1197838

E41LA
Band 4.1-like protein 4A

1

13

High-throughput

0.437

High

1197849

GGA2
ADP-ribosylation factor-binding protein GGA2

1

3

Small-scale

0.437

High

1032493

CTBP1
C-terminal-binding protein 1

1

5

High-throughput

0.407

High

1197812

TEX19
Testis-expressed protein 19

1

0

High-throughput

0.279

Low

1197826

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.279

Low

1197843

FA53C
Protein FAM53C

1

0

High-throughput

0.249

Low

1197853

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024