Protein: Q7K4Q9
Hydroxymethylglutaryl-CoA synthase (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase)

Gene: Q7K4Q9, Hmgs
Organism: Drosophila melanogaster
Interactions: 61
UniProt ID: Q7K4Q9

Gene Ontology (top 5):
GO:0004421 - hydroxymethylglutaryl-CoA synthase activity
GO:0006084 - acetyl-CoA metabolic process
GO:0010142 - farnesyl diphosphate biosynthetic process, mevalonate pathway
GO:0016126 - sterol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

146114

CH60A
Heat shock protein 60A

2

1

High-throughput

0.521

High

628949

OTE
Otefin

2

1

High-throughput

0.521

High

661939

PP2A
Serine/threonine-protein phosphatase PP2A

2

1

High-throughput

0.521

High

726349

VATB
V-type proton ATPase subunit B

2

1

High-throughput

0.521

High

1265994

Q7K3M6
GH28654p

2

1

High-throughput

0.521

High

1266610

C6A13
Probable cytochrome P450 6a13

2

2

High-throughput

0.521

High

1266616

SPE
Spaetzle-processing enzyme

2

1

High-throughput

0.521

High

1266618

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

1

High-throughput

0.521

High

1266619

CP9F2
Probable cytochrome P450 9f2

2

2

High-throughput

0.521

High

1266631

Q9W0D9
choline-phosphate cytidylyltransferase

2

1

High-throughput

0.521

High

94994

E1JGS7
Jitterbug, isoform I

1

1

High-throughput

0.439

High

119654

M9PB07
Daedalus, isoform B

1

1

High-throughput

0.437

High

119900

M9PBM3
Cysteine protease

1

1

High-throughput

0.437

High

1257855

BOCKS
LEM domain-containing protein Bocksbeutel

1

1

High-throughput

0.437

High

1266601

Q8IR76
FAD synthase

1

1

High-throughput

0.437

High

1266617

CP6D4
Probable cytochrome P450 6d4

1

2

High-throughput

0.437

High

1266633

Q9W205
Jitterbug, isoform F

1

1

High-throughput

0.417

High

875065

VATA1
V-type proton ATPase catalytic subunit A isoform 1

1

2

High-throughput

0.407

High

1266383

Q7K4C7
choline-phosphate cytidylyltransferase

1

1

High-throughput

0.407

High

1266603

Q95TS8
Daedalus, isoform A

1

1

High-throughput

0.407

High

1266620

Q9VIM6
GH22016p

1

1

High-throughput

0.407

High

1266625

Q9VPW2
Cysteine protease

1

1

High-throughput

0.407

High

1266629

Q9VYI5
FAD synthase

1

1

High-throughput

0.407

High

53433

A1Z7S4
Uncharacterized protein, isoform D

2

0

High-throughput

0.298

High

705013

EXU
Maternal protein exuperantia

2

0

High-throughput

0.298

High

930145

VATE
V-type proton ATPase subunit E

2

0

High-throughput

0.298

High

1261249

Q7JPS2
Igloo, isoform A

2

0

High-throughput

0.298

High

1266599

Q7K4R2
LD26477p

2

0

High-throughput

0.298

High

1266602

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

2

0

High-throughput

0.298

High

1266613

Q9VAN7
Phosphoglycerate mutase

2

0

High-throughput

0.298

High

1266615

SIL1
Nucleotide exchange factor Sil1

2

0

High-throughput

0.298

High

1266621

Q9VJZ5
LD07294p

2

0

High-throughput

0.298

High

1266623

Q9VP78
GH23156p

2

0

High-throughput

0.298

High

1266624

Q9VP87
Decaprenyl diphosphate synthase subunit 2, isoform A

2

0

High-throughput

0.298

High

1266626

Q9VQI6
LD25952p

2

0

High-throughput

0.298

High

1266632

Q9W0N8
Retinoid-inducible serine carboxypeptidase

2

0

High-throughput

0.298

High

1266635

LST8
Protein LST8 homolog

2

0

High-throughput

0.298

High

1266637

EAF3
NuA4 complex subunit EAF3 homolog

2

0

High-throughput

0.298

High

85794

B8A405
Ferritin

1

0

High-throughput

0.249

Low

1266622

RPF1
Probable ribosome production factor 1

1

0

High-throughput

0.249

Low

1266627

Q9VVY4
Falten, isoform B

1

0

High-throughput

0.249

Low

1266628

TNG2
Transport and Golgi organization protein 2

1

0

High-throughput

0.249

Low

1266630

Q9VYT5
NudC domain-containing protein 1

1

0

High-throughput

0.249

Low

1266634

Q9W316
Carbonic anhydrase-related protein B, isoform A

1

0

High-throughput

0.249

Low

1266636

DNK
Deoxynucleoside kinase

1

0

High-throughput

0.249

Low

69083

A8JRH3
FI20012p1

1

0

High-throughput

0.232

Low

91306

C6SV36
IP19903p

1

0

High-throughput

0.232

Low

234845

O46070
EG:25E8.4 protein

1

0

High-throughput

0.232

Low

384902

HSP26
Heat shock protein 26

1

0

High-throughput

0.232

Low

1266018

Q7K3N4
GH26015p

1

0

High-throughput

0.232

Low

1266600

Q7KMS3
Dynein light chain roadblock

1

0

High-throughput

0.232

Low

1266604

Q95TZ0
phosphoribosylaminoimidazolesuccinocarboxamide synthase

1

0

High-throughput

0.232

Low

1266605

Q961H2
GH23453p

1

0

High-throughput

0.232

Low

1266606

Q961H6
GH23019p

1

0

High-throughput

0.232

Low

1266607

Q961J8
GH20109p

1

0

High-throughput

0.232

Low

1266608

VATH
V-type proton ATPase subunit H

1

0

High-throughput

0.232

Low

1266609

Q9V3K7
Leucine carboxyl methyltransferase 1

1

0

High-throughput

0.232

Low

1266611

VATD1
V-type proton ATPase subunit D 1

1

0

High-throughput

0.232

Low

1266612

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.232

Low

1266614

Q9VBT1
CHK kinase-like domain-containing protein

1

0

High-throughput

0.232

Low

1266638

NWK
Protein nervous wreck

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025