Protein: PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1-alpha) (PPAR-gamma coactivator 1-alpha) (PPARGC-1-alpha)

Gene: PRGC1, Ppargc1a
Organism: Mus musculus
Interactions: 26
UniProt ID: O70343

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0001933 - negative regulation of protein phosphorylation
GO:0002021 - response to dietary excess
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

250746

SIR1
NAD-dependent protein deacetylase sirtuin-1

2

1

Small-scale

0.669

High

250729

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.647

High

250741

EWS
RNA-binding protein EWS

1

1

Small-scale

0.618

High

250737

CDK7
Cyclin-dependent kinase 7

1

0

Small-scale

0.586

High

250728

CEBPB
CCAAT/enhancer-binding protein beta

2

2

Small-scale

0.584

High

250732

PPARG
Peroxisome proliferator-activated receptor gamma

2

20

Small-scale

0.584

High

250730

STF1
Steroidogenic factor 1

1

14

Small-scale

0.573

High

250735

TYY1
Transcriptional repressor protein YY1

1

0

Small-scale

0.564

High

250736

CREB1
Cyclic AMP-responsive element-binding protein 1

2

0

Small-scale

0.559

High

250738

NR1H4
Bile acid receptor

1

20

Small-scale

0.515

High

250742

IRF4
Interferon regulatory factor 4

1

0

Small-scale

0.512

High

139246

ERR1
Steroid hormone receptor ERR1

1

20

Small-scale

0.501

High

250734

ERR3
Estrogen-related receptor gamma

1

20

Small-scale

0.501

High

250740

ERR2
Steroid hormone receptor ERR2

1

20

Small-scale

0.501

High

250743

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

Small-scale

0.501

High

250749

NR1H3
Oxysterols receptor LXR-alpha

1

20

High-throughput

0.481

High

56924

PRD16
Histone-lysine N-methyltransferase PRDM16

1

1

Small-scale

0.479

High

250726

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

1

Small-scale

0.479

High

250727

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.479

High

250733

HNF4A
Hepatocyte nuclear factor 4-alpha

1

18

Small-scale

0.479

High

250739

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

1

Small-scale

0.479

High

250745

FBXW7
F-box/WD repeat-containing protein 7

1

1

Small-scale

0.479

High

250747

MED1
Mediator of RNA polymerase II transcription subunit 1

1

1

Small-scale

0.479

High

250731

DDIT3
DNA damage-inducible transcript 3 protein

1

0

Small-scale

0.458

High

250744

MBB1A
Myb-binding protein 1A

1

0

Small-scale

0.458

High

250748

PRAF1
Prenylated Rab acceptor protein 1

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024