Protein: ZEST
Regulatory protein zeste

Gene: ZEST, z
Organism: Drosophila melanogaster
Interactions: 41
UniProt ID: P09956

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005705 - polytene chromosome interband
GO:0010628 - positive regulation of gene expression
GO:0031507 - heterochromatin formation
GO:0043565 - sequence-specific DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

488671

ZEST
Regulatory protein zeste

4

0

Small-scale

0.653

High

488683

Q7KNM2
Dorsal interacting protein 4

3

0

High-throughput

0.625

High

488695

Q9VF03
Brahma associated protein 155 kDa

1

1

Small-scale

0.578

High

488680

Q7JWW6
Adenosine kinase

2

0

High-throughput

0.569

High

488681

Q7JX41
Geminin

2

0

High-throughput

0.569

High

488687

THIOT
Thioredoxin-T

2

0

High-throughput

0.569

High

488675

PHP
Polyhomeotic-proximal chromatin protein

2

0

Small-scale

0.559

High

488686

MMD4
Modifier of mdg4

1

0

Small-scale

0.529

High

120231

M9PCZ7
SoxNeuro, isoform B

1

0

High-throughput

0.518

High

488673

BRM
ATP-dependent helicase brm

1

0

Small-scale

0.513

High

52079

A1Z6M0
Brahma associated protein 170kD

1

1

Small-scale

0.501

High

488682

Q7KMJ0
BcDNA.GH12174

1

1

Small-scale

0.501

High

488684

Q7KPY3
Moira

1

1

Small-scale

0.501

High

488692

Q9BIW6
Brahma-associated protein 111kD

1

1

Small-scale

0.501

High

488703

Q9W384
Brahma associated protein 111kD

1

1

Small-scale

0.501

High

488679

Q5BIG7
RE55465p

1

1

High-throughput

0.494

High

488672

POXM
Paired box pox-meso protein

1

0

High-throughput

0.486

High

488674

ABDA
Homeobox protein abdominal-A

1

1

High-throughput

0.481

High

488676

UBX
Homeotic protein ultrabithorax

1

1

High-throughput

0.481

High

488704

Q9XYM5
LD27861p

1

1

High-throughput

0.481

High

488688

OSA
Trithorax group protein osa

1

0

Small-scale

0.480

High

488678

EWG
DNA-binding protein Ewg

1

0

High-throughput

0.460

High

477665

SUHW
Zinc finger protein su(Hw)

1

0

Small-scale

0.458

High

2383

A0A0B4KFE8
Uncharacterized protein, isoform B

1

2

High-throughput

0.457

High

488702

Q9W2F0
LD45439p

1

1

High-throughput

0.439

High

488701

Q9W0B3
Vacuolar protein sorting-associated protein VTA1 homolog

3

0

High-throughput

0.340

High

488677

CDC37
Hsp90 co-chaperone Cdc37

2

0

High-throughput

0.310

High

488690

DYLT
Dynein light chain Tctex-type

2

0

High-throughput

0.310

High

488694

PFD5
Probable prefoldin subunit 5

2

0

High-throughput

0.310

High

488697

Q9VVT4
IP10578p

2

0

High-throughput

0.310

High

488700

Q9VZJ1
Protein dpy-30 homolog

2

0

High-throughput

0.310

High

56616

A1ZAC8
Uncharacterized protein, isoform B

1

0

High-throughput

0.265

Low

305094

PELI
Protein pellino

1

0

High-throughput

0.265

Low

488691

GIT
ARF GTPase-activating protein Git

1

0

High-throughput

0.265

Low

488693

DGT6
Augmin complex subunit dgt6

1

0

High-throughput

0.265

Low

488696

Q9VUL2
GH20023p

1

0

High-throughput

0.265

Low

488698

Q9VWG6
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

488689

Q8IQQ3
Limpet, isoform D

1

0

High-throughput

0.257

Low

488685

Q7KUQ6
Limpet, isoform K

1

0

High-throughput

0.251

Low

488699

RL371
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025