Protein: BRM
ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma)

Gene: BRM
Organism: Drosophila melanogaster
Interactions: 90
UniProt ID: P25439

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0001223 - transcription coactivator binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004386 - helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

674046

Q9VF03
Brahma associated protein 155 kDa

10

20

Small-scale

0.974

High

674022

Q7K012
Brahma associated protein 55kD

8

20

Small-scale

0.964

High

534416

ACT1
Actin-5C

5

17

Small-scale

0.912

High

386972

ACT2
Actin-42A

4

17

Small-scale

0.878

High

674041

Q9VC36
Polybromo

4

20

Small-scale

0.875

High

674015

Q24090
GH08712p

10

11

Small-scale

0.748

High

674064

BAP60
Brahma-associated protein of 60 kDa

9

17

Small-scale

0.748

High

674069

Q9W384
Brahma associated protein 111kD

7

20

Small-scale

0.741

High

674027

OSA
Trithorax group protein osa

8

20

Small-scale

0.741

High

674032

EBI
F-box-like/WD repeat-containing protein ebi

2

12

High-throughput

0.737

High

674062

SAYP
Supporter of activation of yellow protein

1

20

Small-scale

0.730

High

674050

Q9VLX2
Bromodomain containing 7/9

1

20

Small-scale

0.647

High

674020

YAP1
Transcriptional coactivator yorkie

3

10

Small-scale

0.640

High

52081

A1Z6M0
Brahma associated protein 170kD

3

13

Small-scale

0.633

High

674056

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

3

20

Small-scale

0.633

High

674048

RUVB1
RuvB-like helicase 1

1

10

Small-scale

0.625

High

121973

M9PH39
histone acetyltransferase

1

20

Small-scale

0.618

High

381692

H3
Histone H3

1

20

Small-scale

0.618

High

402258

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

8

Small-scale

0.618

High

674006

BRM
ATP-dependent helicase brm

1

17

Small-scale

0.618

High

674039

SEC13
Protein SEC13 homolog

1

12

Small-scale

0.618

High

674040

ASF1
Histone chaperone asf1

1

11

Small-scale

0.618

High

263807

CLOCK
Circadian locomoter output cycles protein kaput

2

9

Small-scale

0.584

High

674007

SCAL
Protein scalloped

2

6

Small-scale

0.584

High

674070

Q9W3G1
Uncharacterized protein, isoform A

1

20

High-throughput

0.575

High

674010

DSH
Segment polarity protein dishevelled

2

1

High-throughput

0.571

High

674029

MED6
Mediator of RNA polymerase II transcription subunit 6

2

1

High-throughput

0.571

High

674036

Q9BIW6
Brahma-associated protein 111kD

2

20

Small-scale

0.571

High

674045

MED17
Mediator of RNA polymerase II transcription subunit 17

2

1

High-throughput

0.571

High

674055

MED24
Mediator of RNA polymerase II transcription subunit 24

2

1

High-throughput

0.571

High

674057

CDK8
Cyclin-dependent kinase 8

2

4

High-throughput

0.571

High

674058

Q9VUB7
PAX-interacting protein 1

2

18

High-throughput

0.571

High

674067

MED14
Mediator of RNA polymerase II transcription subunit 14

2

12

High-throughput

0.571

High

674074

MED15
Mediator of RNA polymerase II transcription subunit 15

2

18

High-throughput

0.571

High

674011

CCNE
G1/S-specific cyclin-E

2

5

Small-scale

0.552

High

674047

TCTP
Translationally-controlled tumor protein homolog

1

1

Small-scale

0.552

High

58460

MED8
Mediator of RNA polymerase II transcription subunit 8

2

0

High-throughput

0.547

High

674051

MED27
Mediator of RNA polymerase II transcription subunit 27

2

0

High-throughput

0.547

High

674066

MED30
Mediator of RNA polymerase II transcription subunit 30

2

0

High-throughput

0.547

High

674068

MED23
Mediator of RNA polymerase II transcription subunit 23

2

0

High-throughput

0.547

High

674073

MED18
Mediator of RNA polymerase II transcription subunit 18

2

0

High-throughput

0.547

High

674026

LASP1
LIM and SH3 domain protein Lasp

2

2

High-throughput

0.542

High

674028

ENC
Protein encore

2

3

High-throughput

0.521

High

674034

Q960F7
SD03629p

2

7

High-throughput

0.521

High

674038

LAR4
La-related protein Larp4B

2

8

High-throughput

0.521

High

674065

Q9W0L7
ubiquitinyl hydrolase 1

2

6

High-throughput

0.521

High

538224

HSP7D
Heat shock 70 kDa protein cognate 4

1

10

Small-scale

0.515

High

674008

ECR
Ecdysone receptor

1

20

Small-scale

0.515

High

674012

UBX
Homeotic protein ultrabithorax

1

7

Small-scale

0.515

High

674014

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

6

High-throughput

0.514

High

488673

ZEST
Regulatory protein zeste

1

0

Small-scale

0.513

High

56975

A1ZAK9
P-element somatic inhibitor, isoform A

1

16

High-throughput

0.479

High

119935

M9PBS1
Earmuff, isoform B

1

4

Small-scale

0.479

High

120165

M9PCJ7
Utx histone demethylase, isoform E

1

7

Small-scale

0.479

High

120276

M9PD17
Gigas, isoform B

1

2

High-throughput

0.479

High

304929

CRY1
Cryptochrome-1

1

1

High-throughput

0.479

High

528892

TWIST
Protein twist

1

20

Small-scale

0.479

High

674013

GAGA
Transcription activator GAGA

1

20

Small-scale

0.479

High

674016

SIMA
Protein similar

1

9

High-throughput

0.479

High

674017

DSOR1
Dual specificity mitogen-activated protein kinase kinase dSOR1

1

2

High-throughput

0.479

High

674018

RBF
Retinoblastoma family protein

1

5

Small-scale

0.479

High

674024

Q7KTS4
Histone deacetylase

1

20

Small-scale

0.479

High

674031

Q8T9L5
Serine/threonine-protein kinase STK11

1

3

High-throughput

0.479

High

674033

FOXO
Forkhead box protein O

1

20

High-throughput

0.479

High

674042

Q9VCC9
LD23779p

1

18

High-throughput

0.479

High

674052

Q9VQ58
BRCA2-interacting transcriptional repressor EMSY

1

1

High-throughput

0.479

High

674053

Q9VR61
non-specific serine/threonine protein kinase

1

5

High-throughput

0.479

High

674063

Q9VWJ6
FI03615p

1

3

High-throughput

0.479

High

674071

MYC
Myc proto-oncogene protein

1

20

Small-scale

0.479

High

674009

TIM
Protein timeless

1

0

Small-scale

0.458

High

674021

Q7JX41
Geminin

1

0

Small-scale

0.458

High

674054

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.458

High

674059

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.458

High

674061

ELYS
Protein ELYS homolog

1

0

Small-scale

0.458

High

56928

A1ZAK7
LD35640p

1

16

High-throughput

0.445

High

674019

NETB
Netrin-B

1

4

High-throughput

0.445

High

674025

MED13
Mediator of RNA polymerase II transcription subunit 13

1

2

High-throughput

0.445

High

674043

MED25
Mediator of RNA polymerase II transcription subunit 25

1

11

High-throughput

0.445

High

674044

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

1

6

High-throughput

0.445

High

674060

MED12
Mediator of RNA polymerase II transcription subunit 12

1

19

High-throughput

0.445

High

674072

Q9XZ21
Something that sticks like glue, isoform A

1

16

High-throughput

0.445

High

119560

M9PAY7
Pi3K21B, isoform C

1

9

High-throughput

0.437

High

197439

O18353
CHIP

1

0

High-throughput

0.426

High

674023

MED29
Mediator of RNA polymerase II transcription subunit 29

1

0

High-throughput

0.426

High

674037

MED10
Mediator of RNA polymerase II transcription subunit 10

1

0

High-throughput

0.426

High

674049

Q9VL29
GEO11246p1

1

0

High-throughput

0.426

High

262731

TENM
Teneurin-m

1

4

High-throughput

0.407

High

674035

Q961D0
LD22190p

1

14

High-throughput

0.348

High

674030

MESD
LDLR chaperone boca

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025