Protein: SPEN
Protein split ends

Gene: SPEN
Organism: Drosophila melanogaster
Interactions: 18
UniProt ID: Q8SX83

Gene Ontology (top 5):
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0006355 - regulation of DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0007379 - segment specification

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

911741

POLO
Serine/threonine-protein kinase polo

1

1

High-throughput

0.698

High

1343639

Q9W0Q1
non-specific serine/threonine protein kinase

1

20

Small-scale

0.647

High

1343638

CDK12
Cyclin-dependent kinase 12

1

11

High-throughput

0.637

High

614087

SGG
Protein kinase shaggy

1

16

High-throughput

0.575

High

2477

NOVA
RNA-binding protein Pasilla

1

20

High-throughput

0.484

High

1175003

NETB
Netrin-B

1

3

High-throughput

0.484

High

1306738

TRR
Histone-lysine N-methyltransferase trr

1

11

Small-scale

0.479

High

56636

A1ZAC8
Uncharacterized protein, isoform B

1

1

High-throughput

0.464

High

1343634

Q9VC48
Methionine aminopeptidase

1

2

High-throughput

0.464

High

1343635

Q9VH81
protein-serine/threonine phosphatase

1

20

High-throughput

0.445

High

1343633

Q9GU50
GH09802p

1

4

High-throughput

0.439

High

1306578

Q8IRK7
Misexpression suppressor of KSR 2, isoform D

1

4

High-throughput

0.417

High

1343637

Q9VN49
Smallish, isoform I

1

2

High-throughput

0.417

High

1070598

Q0KHS0
Katanin p80 WD40 repeat-containing subunit B1

1

20

High-throughput

0.407

High

1246548

Q6QU65
ADAM metalloprotease

1

1

High-throughput

0.407

High

234855

O46070
EG:25E8.4 protein

1

0

High-throughput

0.265

Low

1343636

Q9VLR0
FI06011p

1

0

High-throughput

0.265

Low

1071076

Y3427
Uncharacterized protein CG43427

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025