HitPredict

Interactor 1: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33306668, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 496
+	Sc
		792390 TCPH_YEAST (2-542): 0: 587: 62.45		CDH1_YEAST (44-496): 7.57e-103: 320: 37.81
+	Hs
		1306645 TCPH_HUMAN (1-543): 0: 647: 100.00		TBL1Y_HUMAN (99-430): 2.64e-70: 234: 16.20
+	At
		1351754 TCPH_ARATH (1-529): 0: 583: 67.67		CD203_ARATH (37-495): 2.18e-92: 289: 35.55
+	Hs
		1306704 TCPH_HUMAN (1-543): 0: 647: 100.00		NLE1_HUMAN (52-385): 3.28e-60: 207: 16.32
+	Hs
		826807 TCPG_HUMAN (1-541): 0: 577: 31.09		FBXW7_HUMAN (87-424): 1.7e-71: 242: 18.68
+	Hs
		826848 TCPG_HUMAN (1-541): 0: 577: 31.09		TBL1Y_HUMAN (99-430): 2.64e-70: 234: 16.20
+	Hs
		792942 TCPG_HUMAN (1-541): 0: 577: 31.09		LIS1_HUMAN (309-495): 7.12e-53: 185: 19.68
+	Hs
		903467 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		1240450 TCPH_HUMAN (1-543): 0: 647: 100.00		POC1A_HUMAN (68-215): 1.37e-12: 71.1: 10.60
+	Hs
		1202777 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5B_HUMAN (408-495): 1.82e-11: 67.3: 16.15
+	Hs
		1017427 TCPH_HUMAN (1-543): 0: 647: 100.00		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	At
		1352093 TCPH_ARATH (1-529): 0: 583: 67.67		CDC21_ARATH (334-495): 4.51e-28: 118: 19.08
+	Hs
		826784 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1B_HUMAN (31-259): 4.34e-30: 124: 13.19
+	Hs
		826601 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5_HUMAN (389-496): 1.49e-26: 111: 18.35
+	Hs
		826938 TCPG_HUMAN (1-541): 0: 577: 31.09		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	At
		1225851 TCPH_ARATH (1-529): 0: 583: 67.67		FZR2_ARATH (319-495): 7.11e-20: 94.2: 22.22
+	Sc
		640850 TCPH_YEAST (2-542): 0: 587: 62.45		CDC20_YEAST (319-488): 5.34e-14: 76.2: 18.50
+	Hs
		826772 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1A_HUMAN (68-215): 1.37e-12: 71.1: 10.60
+	Hs
		826748 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5B_HUMAN (408-495): 1.82e-11: 67.3: 16.15
+	Hs
		826632 TCPG_HUMAN (1-541): 0: 577: 31.09		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67