HitPredict

Interactor 1: ARL8A (Q96BM9)
ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2)
Gene: ARL8A

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~PH
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 186 Hs			1 779
+	Hs
		913111 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		950712 ARF5_HUMAN (11-184): 2.76e-86: 253: 29.89		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1328144 RAB1B_HUMAN (21-185): 1.28e-69: 211: 23.67		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		918949 RAB1A_HUMAN (21-185): 1.3e-69: 211: 23.67		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		897405 ARF3_HUMAN (1-185): 2.14e-65: 200: 30.27		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		950560 ARF1_HUMAN (1-185): 2.78e-65: 199: 30.81		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		912962 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		912879 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		912946 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		950634 ARF5_HUMAN (11-184): 2.76e-86: 253: 29.89		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		912911 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		ACAP2_HUMAN (28-517): 6.24e-39: 156: 13.10
+	Hs
		913123 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		PKHA1_HUMAN (16-261): 3.76e-39: 151: 16.92
+	Hs
		913121 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		1148944 ARL8A_HUMAN (1-186): 8.03e-69: 209: 100.00		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		897369 ARF3_HUMAN (1-185): 2.14e-65: 200: 30.27		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		950502 ARF1_HUMAN (1-185): 2.78e-65: 199: 30.81		RHG21_HUMAN (22-662): 1.96e-43: 172: 13.18
+	Hs
		913206 ARF6_HUMAN (12-183): 1.07e-86: 253: 33.72		FARP1_HUMAN (6-167): 1.07e-24: 112: 17.96
+	Hs
		1328146 RAB1B_HUMAN (21-185): 1.28e-69: 211: 23.67		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90
+	Mm
		950587 ARF1_MOUSE (1-185): 2.78e-65: 199: 30.81		RHG21_MOUSE (22-626): 1.41e-38: 157: 14.13
+	Hs
		950539 ARF1_HUMAN (1-185): 2.78e-65: 199: 30.81		PKHA8_HUMAN (57-356): 1.52e-38: 152: 14.89