Protein: KDM5C
Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C)

Gene: KDM5C
Organism: Homo sapiens
Interactions: 113
UniProt ID: P41229

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782398

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

2

7

High-throughput

0.754

High

782332

EWS
RNA-binding protein EWS

1

3

High-throughput

0.691

High

782338

CBX3
Chromobox protein homolog 3

1

3

Small-scale

0.691

High

782339

TIF1B
Transcription intermediary factor 1-beta

1

3

High-throughput

0.691

High

782381

BRD8
Bromodomain-containing protein 8

1

11

High-throughput

0.691

High

782389

ASH1L
Histone-lysine N-methyltransferase ASH1L

1

15

High-throughput

0.691

High

782360

SCML4
Sex comb on midleg-like protein 4

3

2

High-throughput

0.667

High

782400

LHX6
LIM/homeobox protein Lhx6

3

7

High-throughput

0.667

High

782353

H32
Histone H3.2

3

20

Small-scale

0.655

High

317656

CNOT4
CCR4-NOT transcription complex subunit 4

1

2

Small-scale

0.647

High

782378

IER2
Immediate early response gene 2 protein

3

0

High-throughput

0.638

High

265612

E2F6
Transcription factor E2F6

2

1

Small-scale

0.628

High

782324

MAX
Protein max

2

3

Small-scale

0.628

High

782340

SKP2
S-phase kinase-associated protein 2

2

3

High-throughput

0.628

High

782366

SSH3
Protein phosphatase Slingshot homolog 3

2

1

High-throughput

0.628

High

782402

TRI35
E3 ubiquitin-protein ligase TRIM35

2

6

High-throughput

0.628

High

782358

MGAP
MAX gene-associated protein

2

3

Small-scale

0.618

High

244060

BRD4
Bromodomain-containing protein 4

1

9

High-throughput

0.618

High

782318

KDM5C
Lysine-specific demethylase 5C

1

12

Small-scale

0.618

High

782323

SMCA4
Transcription activator BRG1

1

14

Small-scale

0.618

High

782356

PB1
Protein polybromo-1

1

19

Small-scale

0.618

High

782401

TRI33
E3 ubiquitin-protein ligase TRIM33

1

5

High-throughput

0.618

High

782319

RHG25
Rho GTPase-activating protein 25

3

2

High-throughput

0.609

High

327268

NOE2
Noelin-2

2

0

High-throughput

0.602

High

782380

IQCN
IQ domain-containing protein N

2

0

High-throughput

0.602

High

782371

TRI11
E3 ubiquitin-protein ligase TRIM11

1

5

Small-scale

0.578

High

782350

DEFI8
Differentially expressed in FDCP 8 homolog

2

1

High-throughput

0.574

High

782337

REST
RE1-silencing transcription factor

1

1

Small-scale

0.565

High

62133

RCCD1
RCC1 domain-containing protein 1

1

1

High-throughput

0.536

High

162467

XPO1
Exportin-1

1

3

High-throughput

0.536

High

199176

ZNHI1
Zinc finger HIT domain-containing protein 1

1

1

High-throughput

0.536

High

261428

NCOR1
Nuclear receptor corepressor 1

1

7

Small-scale

0.536

High

297467

TOX4
TOX high mobility group box family member 4

1

5

High-throughput

0.536

High

474947

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

2

High-throughput

0.536

High

782331

SET
Protein SET

1

3

High-throughput

0.536

High

782333

MBTD1
MBT domain-containing protein 1

1

3

High-throughput

0.536

High

782334

RING1
E3 ubiquitin-protein ligase RING1

1

8

Small-scale

0.536

High

782341

HDAC1
Histone deacetylase 1

1

14

Small-scale

0.536

High

782344

MO4L2
Mortality factor 4-like protein 2

1

5

High-throughput

0.536

High

782347

EPC2
Enhancer of polycomb homolog 2

1

2

High-throughput

0.536

High

782348

SNPC4
snRNA-activating protein complex subunit 4

1

1

High-throughput

0.536

High

782357

PALB2
Partner and localizer of BRCA2

1

1

High-throughput

0.536

High

782359

ZN687
Zinc finger protein 687

1

2

High-throughput

0.536

High

782361

PIAS4
E3 SUMO-protein ligase PIAS4

1

2

High-throughput

0.536

High

782368

ZN592
Zinc finger protein 592

1

2

High-throughput

0.536

High

782369

HDAC2
Histone deacetylase 2

1

14

Small-scale

0.536

High

782375

EP400
E1A-binding protein p400

1

15

High-throughput

0.536

High

782376

RING2
E3 ubiquitin-protein ligase RING2

1

9

Small-scale

0.536

High

782379

DUS16
Dual specificity protein phosphatase 16

1

1

High-throughput

0.536

High

782382

EPC1
Enhancer of polycomb homolog 1

1

1

High-throughput

0.536

High

782383

TSYL2
Testis-specific Y-encoded-like protein 2

1

3

High-throughput

0.536

High

782387

ZN532
Zinc finger protein 532

1

2

High-throughput

0.536

High

782388

TRI39
E3 ubiquitin-protein ligase TRIM39

1

5

High-throughput

0.536

High

782390

MRGBP
MRG/MORF4L-binding protein

1

1

High-throughput

0.536

High

782391

ING3
Inhibitor of growth protein 3

1

1

High-throughput

0.536

High

782393

FOXJ2
Forkhead box protein J2

1

8

High-throughput

0.536

High

782394

MBD2
Methyl-CpG-binding domain protein 2

1

2

High-throughput

0.536

High

782395

MO4L1
Mortality factor 4-like protein 1

1

5

High-throughput

0.536

High

782405

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.536

High

782408

TF3C3
General transcription factor 3C polypeptide 3

1

1

High-throughput

0.536

High

270958

SPAG6
Sperm-associated antigen 6

1

0

High-throughput

0.513

High

666854

TKT
Transketolase

1

0

High-throughput

0.513

High

729046

K22E
Keratin, type II cytoskeletal 2 epidermal

1

0

High-throughput

0.513

High

782320

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

0

High-throughput

0.513

High

782322

TUB
Tubby protein homolog

1

0

High-throughput

0.513

High

782326

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.513

High

782336

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.513

High

782362

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.513

High

782367

TF3C2
General transcription factor 3C polypeptide 2

1

0

High-throughput

0.513

High

782370

EFMT3
EEF1A lysine methyltransferase 3

1

0

High-throughput

0.513

High

782372

ZN764
Zinc finger protein 764

1

0

High-throughput

0.513

High

782373

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

782377

CENPK
Centromere protein K

1

0

High-throughput

0.513

High

782384

TXNIP
Thioredoxin-interacting protein

1

0

High-throughput

0.513

High

782386

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.513

High

782397

FBX10
F-box only protein 10

1

0

High-throughput

0.513

High

782399

SUFU
Suppressor of fused homolog

1

0

High-throughput

0.513

High

782403

SATB2
DNA-binding protein SATB2

1

0

High-throughput

0.513

High

782406

ATG4B
Cysteine protease ATG4B

1

0

High-throughput

0.513

High

782407

TF3C5
General transcription factor 3C polypeptide 5

1

0

High-throughput

0.513

High

782409

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.513

High

261965

PEX14
Peroxisomal membrane protein PEX14

1

1

High-throughput

0.501

High

782325

SUMO2
Small ubiquitin-related modifier 2

1

2

High-throughput

0.501

High

782374

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

2

Small-scale

0.500

High

782404

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

3

Small-scale

0.500

High

282314

NEBL
Nebulette

1

2

High-throughput

0.489

High

782327

TBA1B
Tubulin alpha-1B chain

1

4

High-throughput

0.489

High

782343

TFDP1
Transcription factor Dp-1

1

0

Small-scale

0.479

High

386243

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

517117

PCNA
Proliferating cell nuclear antigen

1

2

Small-scale

0.479

High

782321

MXI1
Max-interacting protein 1

1

5

Small-scale

0.479

High

782328

CSK21
Casein kinase II subunit alpha

1

2

High-throughput

0.479

High

782329

SMAD3
Mothers against decapentaplegic homolog 3

1

1

Small-scale

0.479

High

782342

CUL3
Cullin-3

1

5

High-throughput

0.479

High

782351

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

782354

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

782363

FBX22
F-box only protein 22

1

3

High-throughput

0.479

High

782364

NUP43
Nucleoporin Nup43

1

17

High-throughput

0.479

High

782365

SMRC2
SWI/SNF complex subunit SMARCC2

1

17

Small-scale

0.479

High

299329

UBXN7
UBX domain-containing protein 7

1

0

High-throughput

0.458

High

782355

SLN11
Schlafen family member 11

1

0

High-throughput

0.458

High

782392

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

782396

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

91523

E7EU96
Casein kinase II subunit alpha

1

1

High-throughput

0.445

High

782352

E400N
Putative EP400-like protein

1

1

High-throughput

0.407

High

673942

HLAF
HLA class I histocompatibility antigen, alpha chain F

3

0

High-throughput

0.347

High

782330

NDP
Norrin

1

0

High-throughput

0.279

Low

782345

CART

1

0

High-throughput

0.279

Low

782346

INSC
Protein inscuteable homolog

1

0

High-throughput

0.279

Low

782349

SPAT1
Spermatogenesis-associated protein 1

1

0

High-throughput

0.279

Low

782385

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.279

Low

782335

YL016
Putative uncharacterized protein LOC100128554

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024