Protein: VP37C
Vacuolar protein sorting-associated protein 37C (hVps37C) (ESCRT-I complex subunit VPS37C)

Gene: VP37C, VPS37C
Organism: Homo sapiens
Interactions: 140
UniProt ID: A5D8V6

Gene Ontology (top 5):
GO:0000813 - ESCRT I complex
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0005929 - cilium
GO:0006612 - protein targeting to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

63253

TS101
Tumor susceptibility gene 101 protein

8

12

Small-scale

0.972

High

63277

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

8

Small-scale

0.768

High

63185

XIAP
E3 ubiquitin-protein ligase XIAP

4

5

High-throughput

0.698

High

63150

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

3

4

High-throughput

0.675

High

63159

PDCD6
Programmed cell death protein 6

3

6

High-throughput

0.675

High

63160

STAM2
Signal transducing adapter molecule 2

3

20

High-throughput

0.675

High

63242

TFG
Protein TFG

3

8

High-throughput

0.675

High

63243

RBPMS
RNA-binding protein with multiple splicing

3

1

High-throughput

0.675

High

63208

CEP55
Centrosomal protein of 55 kDa

4

3

Small-scale

0.646

High

63152

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

18

Small-scale

0.633

High

63166

HXB5
Homeobox protein Hox-B5

2

5

High-throughput

0.628

High

63179

PKNX1
Homeobox protein PKNOX1

4

3

High-throughput

0.623

High

63247

MB12A
Multivesicular body subunit 12A

1

7

Small-scale

0.618

High

63156

VINEX
Vinexin

3

20

High-throughput

0.616

High

63163

SRBS2
Sorbin and SH3 domain-containing protein 2

3

20

High-throughput

0.616

High

63173

DDIT3
DNA damage-inducible transcript 3 protein

3

1

High-throughput

0.616

High

63188

TLE5
TLE family member 5

3

2

High-throughput

0.616

High

63234

MISSL
MAPK-interacting and spindle-stabilizing protein-like

3

8

High-throughput

0.616

High

50304

F168B
Myelin-associated neurite-outgrowth inhibitor

2

1

High-throughput

0.606

High

63149

EYA2
Protein phosphatase EYA2

2

11

High-throughput

0.606

High

63176

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

2

2

High-throughput

0.606

High

63177

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

6

High-throughput

0.606

High

63180

PAX9
Paired box protein Pax-9

2

16

High-throughput

0.606

High

63181

GRB2
Growth factor receptor-bound protein 2

2

20

High-throughput

0.606

High

63186

TIAR
Nucleolysin TIAR

2

4

High-throughput

0.606

High

63187

RUNX1
Runt-related transcription factor 1

2

5

High-throughput

0.606

High

63190

ILF3
Interleukin enhancer-binding factor 3

2

12

High-throughput

0.606

High

63191

FOXI1
Forkhead box protein I1

2

13

High-throughput

0.606

High

63192

GPS2
G protein pathway suppressor 2

2

1

High-throughput

0.606

High

63193

KLF1
Krueppel-like factor 1

2

20

High-throughput

0.606

High

63237

SH3R2
E3 ubiquitin-protein ligase SH3RF2

2

20

High-throughput

0.606

High

63244

FUBP1
Far upstream element-binding protein 1

2

5

High-throughput

0.606

High

63245

BIRC7
Baculoviral IAP repeat-containing protein 7

2

5

High-throughput

0.606

High

63251

PKNX2
Homeobox protein PKNOX2

2

4

High-throughput

0.606

High

63265

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

2

4

High-throughput

0.606

High

63268

WWOX
WW domain-containing oxidoreductase

2

2

High-throughput

0.606

High

63270

PEF1
Peflin

2

7

High-throughput

0.606

High

63167

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

11

High-throughput

0.602

High

63255

SH3G1
Endophilin-A2

3

20

High-throughput

0.597

High

63195

KT33B
Keratin, type I cuticular Ha3-II

2

0

High-throughput

0.580

High

63196

LAGE3
EKC/KEOPS complex subunit LAGE3

2

0

High-throughput

0.580

High

63221

K1C27
Keratin, type I cytoskeletal 27

2

0

High-throughput

0.580

High

63228

STH
Saitohin

2

0

High-throughput

0.580

High

63254

SPAG8
Sperm-associated antigen 8

2

0

High-throughput

0.580

High

63271

ZMAT5
Zinc finger matrin-type protein 5

2

0

High-throughput

0.580

High

63153

PLS1
Phospholipid scramblase 1

1

2

High-throughput

0.573

High

63169

PSA3
Proteasome subunit alpha type-3

1

3

High-throughput

0.573

High

63189

GOGA2
Golgin subfamily A member 2

1

8

High-throughput

0.573

High

63257

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

8

High-throughput

0.573

High

63280

TACC3
Transforming acidic coiled-coil-containing protein 3

1

11

High-throughput

0.573

High

63155

CRX
Cone-rod homeobox protein

2

20

High-throughput

0.553

High

63162

FCSD2
F-BAR and double SH3 domains protein 2

2

7

High-throughput

0.553

High

63164

BAG4
BAG family molecular chaperone regulator 4

2

1

High-throughput

0.553

High

63197

LASP1
LIM and SH3 domain protein 1

2

20

High-throughput

0.553

High

63202

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.553

High

63204

KR195
Keratin-associated protein 19-5

2

1

High-throughput

0.553

High

63211

UBAP2
Ubiquitin-associated protein 2

2

9

High-throughput

0.553

High

63219

RBPS2
RNA-binding protein with multiple splicing 2

2

1

High-throughput

0.553

High

63220

NUP54
Nucleoporin p54

2

4

High-throughput

0.553

High

63222

P4HA3
Prolyl 4-hydroxylase subunit alpha-3

2

1

High-throughput

0.553

High

63224

AP2D
Transcription factor AP-2-delta

2

2

High-throughput

0.553

High

63258

YTHD1
YTH domain-containing family protein 1

2

2

High-throughput

0.553

High

63264

ASCL3
Achaete-scute homolog 3

2

5

High-throughput

0.553

High

63269

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.549

High

63157

TOM1
Target of Myb1 membrane trafficking protein

1

12

High-throughput

0.536

High

63171

MCM7
DNA replication licensing factor MCM7

1

7

High-throughput

0.536

High

63174

MAGAA
Melanoma-associated antigen 10

1

4

High-throughput

0.536

High

63182

RACK1
Small ribosomal subunit protein RACK1

1

5

High-throughput

0.536

High

63229

ZDH23
Palmitoyltransferase ZDHHC23

1

1

High-throughput

0.536

High

63252

RIT2
GTP-binding protein Rit2

1

12

High-throughput

0.536

High

63266

ANLN
Anillin

1

1

High-throughput

0.536

High

63240

F168A
Protein FAM168A

1

1

High-throughput

0.523

High

63199

ARHG6
Rho guanine nucleotide exchange factor 6

2

2

High-throughput

0.521

High

63273

CIDEB
Lipid transferase CIDEB

1

0

High-throughput

0.513

High

63276

TRM6
tRNA

1

0

High-throughput

0.513

High

63279

SPIN1
Spindlin-1

1

0

High-throughput

0.513

High

63165

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

63275

LCMT1
Leucine carboxyl methyltransferase 1

1

0

High-throughput

0.493

High

63168

BTF3
Transcription factor BTF3

1

1

High-throughput

0.489

High

63212

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

3

High-throughput

0.489

High

63213

FRPD2
FERM and PDZ domain-containing protein 2

1

11

High-throughput

0.489

High

63232

S2541
Mitochondrial carrier protein SCaMC-3L

1

1

High-throughput

0.489

High

63145

VP37C
Vacuolar protein sorting-associated protein 37C

1

8

High-throughput

0.481

High

63223

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

20

High-throughput

0.481

High

63238

PDC6I
Programmed cell death 6-interacting protein

1

13

Small-scale

0.481

High

63151

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

2

High-throughput

0.479

High

63172

MYH9
Myosin-9

1

2

High-throughput

0.479

High

63175

MECP2
Methyl-CpG-binding protein 2

1

5

High-throughput

0.479

High

63178

FOXA1
Hepatocyte nuclear factor 3-alpha

1

15

High-throughput

0.479

High

63236

TNIP2
TNFAIP3-interacting protein 2

1

5

High-throughput

0.479

High

63278

AGO2
Protein argonaute-2

1

2

Small-scale

0.479

High

419

A0A087WSW0
Helt bHLH transcription factor

1

2

High-throughput

0.470

High

63147

B7ZLH0
FAM22F protein

1

3

High-throughput

0.470

High

63148

G4XUV3
Putative hydroxypyruvate isomerase

1

1

High-throughput

0.470

High

63183

PR20D
Proline-rich protein 20D

1

1

High-throughput

0.470

High

63214

Q6FGM0
Endophilin-A2

1

20

High-throughput

0.470

High

63225

Q86WV8
TSC complex subunit 1

1

2

High-throughput

0.470

High

63250

Q96I87
Homeobox-containing protein PKNOX1

1

3

High-throughput

0.470

High

63261

RPB1C
DNA-directed RNA polymerase II subunit RPB11-b2

1

2

High-throughput

0.470

High

63158

MTG16
Protein CBFA2T3

1

0

High-throughput

0.460

High

63230

ZNF34
Zinc finger protein 34

1

0

High-throughput

0.460

High

63218

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

63267

PDLI7
PDZ and LIM domain protein 7

1

5

High-throughput

0.445

High

63272

PARP2
Poly [ADP-ribose] polymerase 2

1

3

Small-scale

0.445

High

51297

NTM2F
NUT family member 2F

1

3

High-throughput

0.439

High

63146

HELT
Hairy and enhancer of split-related protein HELT

1

4

High-throughput

0.439

High

63184

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

63210

HYI
Putative hydroxypyruvate isomerase

1

1

High-throughput

0.439

High

63241

TSC1
Hamartin

1

14

High-throughput

0.439

High

63259

RPB1B
DNA-directed RNA polymerase II subunit RPB11-b1

1

2

High-throughput

0.439

High

63194

TRI14
Tripartite motif-containing protein 14

1

5

High-throughput

0.437

High

63262

PKHA4
Pleckstrin homology domain-containing family A member 4

1

11

High-throughput

0.437

High

63274

UBQL2
Ubiquilin-2

1

7

High-throughput

0.437

High

63198

DAZP2
DAZ-associated protein 2

3

0

High-throughput

0.352

High

63217

CA094
Uncharacterized protein C1orf94

3

0

High-throughput

0.352

High

63154

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

63161

DCTN3
Dynactin subunit 3

2

0

High-throughput

0.316

High

63200

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.316

High

63201

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.316

High

63203

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

63205

KR151
Keratin-associated protein 15-1

2

0

High-throughput

0.316

High

63206

KR197
Keratin-associated protein 19-7

2

0

High-throughput

0.316

High

63207

AARD
Alanine- and arginine-rich domain-containing protein

2

0

High-throughput

0.316

High

63209

PKHG4
Puratrophin-1

2

0

High-throughput

0.316

High

63216

UFSP1
Ufm1-specific protease 1

2

0

High-throughput

0.316

High

63227

KRA71
Keratin-associated protein 7-1

2

0

High-throughput

0.316

High

63231

RIBC1
RIB43A-like with coiled-coils protein 1

2

0

High-throughput

0.316

High

63233

MET27
Methyltransferase-like protein 27

2

0

High-throughput

0.316

High

63235

ABHDB
sn-1-specific diacylglycerol lipase ABHD11

2

0

High-throughput

0.316

High

63239

DYDC1
DPY30 domain-containing protein 1

2

0

High-throughput

0.316

High

63246

HAUS1
HAUS augmin-like complex subunit 1

2

0

High-throughput

0.316

High

63249

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.316

High

63256

RAMAC
RNA guanine-N7 methyltransferase activating subunit

2

0

High-throughput

0.316

High

63260

ZMY12
Zinc finger MYND domain-containing protein 12

2

0

High-throughput

0.316

High

63215

RINT1
RAD50-interacting protein 1

1

0

High-throughput

0.299

High

63226

RFX6
DNA-binding protein RFX6

1

0

High-throughput

0.299

High

63170

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

63248

CERS2
Ceramide synthase 2

1

0

High-throughput

0.279

Low

63263

A4GAT
Lactosylceramide 4-alpha-galactosyltransferase

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025