Protein: GRB7
Growth factor receptor-bound protein 7 (B47) (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)

Gene: GRB7
Organism: Homo sapiens
Interactions: 175
UniProt ID: Q14451

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0007173 - epidermal growth factor receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

383806

ERBB2
Receptor tyrosine-protein kinase erbB-2

7

20

Small-scale

0.965

High

983612

FAK1
Focal adhesion kinase 1

4

20

Small-scale

0.912

High

601921

ERBB3
Receptor tyrosine-protein kinase erbB-3

4

20

Small-scale

0.902

High

499267

KIT
Mast/stem cell growth factor receptor Kit

3

20

Small-scale

0.849

High

441503

MET
Hepatocyte growth factor receptor

2

20

Small-scale

0.789

High

1054047

GRB7
Growth factor receptor-bound protein 7

2

20

Small-scale

0.789

High

1054080

STAC3
SH3 and cysteine-rich domain-containing protein 3

2

20

High-throughput

0.783

High

338432

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.768

High

452424

PGFRB
Platelet-derived growth factor receptor beta

1

20

Small-scale

0.757

High

872614

EPHB1
Ephrin type-B receptor 1

1

20

Small-scale

0.740

High

1054074

RND1
Rho-related GTP-binding protein Rho6

1

20

Small-scale

0.740

High

1054101

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.740

High

666111

SHC1
SHC-transforming protein 1

1

20

Small-scale

0.724

High

1054065

LAX1
Lymphocyte transmembrane adapter 1

4

1

High-throughput

0.698

High

434194

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

20

Small-scale

0.692

High

411384

INSR
Insulin receptor

1

20

Small-scale

0.680

High

1054068

KCTD6
BTB/POZ domain-containing protein KCTD6

3

8

High-throughput

0.675

High

148073

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

3

High-throughput

0.656

High

320468

CPNE6
Copine-6

1

5

High-throughput

0.656

High

921565

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

7

High-throughput

0.656

High

980603

TLE1
Transducin-like enhancer protein 1

1

10

High-throughput

0.656

High

1054054

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

922172

RL31
Large ribosomal subunit protein eL31

3

1

Small-scale

0.633

High

1054117

NOC2L
Nucleolar complex protein 2 homolog

3

2

Small-scale

0.633

High

787484

MTOR
Serine/threonine-protein kinase mTOR

1

5

Small-scale

0.618

High

861752

PLK1
Serine/threonine-protein kinase PLK1

1

15

Small-scale

0.618

High

1044765

RIN1
Ras and Rab interactor 1

1

20

Small-scale

0.618

High

1054066

RPTOR
Regulatory-associated protein of mTOR

1

4

Small-scale

0.618

High

1054097

RGAP1
Rac GTPase-activating protein 1

1

20

Small-scale

0.618

High

1054107

COR1C
Coronin-1C

1

9

Small-scale

0.618

High

1054118

TBL2
Transducin beta-like protein 2

1

8

Small-scale

0.618

High

207168

TGM5
Protein-glutamine gamma-glutamyltransferase 5

2

2

High-throughput

0.606

High

1054102

PICK1
PRKCA-binding protein

2

2

High-throughput

0.606

High

1054113

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

20

High-throughput

0.587

High

322622

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

5

Small-scale

0.584

High

1054070

OLIG1
Oligodendrocyte transcription factor 1

2

4

High-throughput

0.579

High

1054058

LY66F
Lymphocyte antigen 6 complex locus protein G6f

1

1

Small-scale

0.578

High

152963

RIOK3
Serine/threonine-protein kinase RIO3

2

1

High-throughput

0.571

High

241006

RT14
Small ribosomal subunit protein uS14m

2

1

High-throughput

0.571

High

281268

RL1D1
Ribosomal L1 domain-containing protein 1

2

1

High-throughput

0.571

High

574332

RL35A
Large ribosomal subunit protein eL33

2

1

High-throughput

0.571

High

649506

RL10
Large ribosomal subunit protein uL16

2

7

High-throughput

0.571

High

671240

RL12
Large ribosomal subunit protein uL11

2

1

High-throughput

0.571

High

736462

RL4
Large ribosomal subunit protein uL4

2

1

High-throughput

0.571

High

899191

RL15
Large ribosomal subunit protein eL15

2

1

High-throughput

0.571

High

899742

RL27
Large ribosomal subunit protein eL27

2

2

High-throughput

0.571

High

916192

RL23A
Large ribosomal subunit protein uL23

2

1

High-throughput

0.571

High

922058

RL39
Large ribosomal subunit protein eL39

2

2

High-throughput

0.571

High

947563

RT05
Small ribosomal subunit protein uS5m

2

2

High-throughput

0.571

High

989794

RL18
Large ribosomal subunit protein eL18

2

1

High-throughput

0.571

High

1054064

FABD
Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

2

1

High-throughput

0.571

High

1054071

BRX1
Ribosome biogenesis protein BRX1 homolog

2

2

High-throughput

0.571

High

1054079

RL10L
Ribosomal protein uL16-like

2

7

High-throughput

0.571

High

1054083

PURB
Transcriptional regulator protein Pur-beta

2

3

High-throughput

0.571

High

1054092

RIOK2
Serine/threonine-protein kinase RIO2

2

1

High-throughput

0.571

High

1054093

RT26
Small ribosomal subunit protein mS26

2

1

High-throughput

0.571

High

1054115

RT07
Small ribosomal subunit protein uS7m

2

2

High-throughput

0.571

High

271089

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

11

High-throughput

0.553

High

1054076

TRI43
Tripartite motif-containing protein 43

2

15

High-throughput

0.553

High

1054110

PRP19
Pre-mRNA-processing factor 19

1

4

Small-scale

0.553

High

773365

RL13A
Large ribosomal subunit protein uL13

2

0

High-throughput

0.547

High

790399

RL35
Large ribosomal subunit protein uL29

2

0

High-throughput

0.547

High

842499

RL14
Large ribosomal subunit protein eL14

2

0

High-throughput

0.547

High

900157

RL37A
Large ribosomal subunit protein eL43

2

0

High-throughput

0.547

High

921116

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

2

0

High-throughput

0.547

High

922828

RL32
Large ribosomal subunit protein eL32

2

0

High-throughput

0.547

High

947379

RT35
Small ribosomal subunit protein mS35

2

0

High-throughput

0.547

High

948161

RT21
Small ribosomal subunit protein bS21m

2

0

High-throughput

0.547

High

951556

RL19
Large ribosomal subunit protein eL19

2

0

High-throughput

0.547

High

973068

RL6
Large ribosomal subunit protein eL6

2

0

High-throughput

0.547

High

1054062

RIOX2
Ribosomal oxygenase 2

2

0

High-throughput

0.547

High

1054067

RP25L
Ribonuclease P protein subunit p25-like protein

2

0

High-throughput

0.547

High

1054077

RT24
Small ribosomal subunit protein uS3m

2

0

High-throughput

0.547

High

1054089

MMTA2
Multiple myeloma tumor-associated protein 2

2

0

High-throughput

0.547

High

1054099

RPF2
Ribosome production factor 2 homolog

2

0

High-throughput

0.547

High

487429

ANDR
Androgen receptor

1

20

High-throughput

0.536

High

947226

RT10
Small ribosomal subunit protein uS10m

2

2

High-throughput

0.521

High

1054112

L10K
Leydig cell tumor 10 kDa protein homolog

2

1

High-throughput

0.521

High

1054116

RT02
Small ribosomal subunit protein uS2m

2

3

High-throughput

0.521

High

684034

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

2662

A0A0C3SFZ9
FCH and mu domain containing endocytic adaptor 1

1

11

High-throughput

0.515

High

361865

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

2

High-throughput

0.508

High

380208

A1BG
Alpha-1B-glycoprotein

1

20

High-throughput

0.508

High

415328

ATPB
ATP synthase subunit beta, mitochondrial

1

6

High-throughput

0.508

High

537904

KPYM
Pyruvate kinase PKM

1

2

High-throughput

0.508

High

550774

RS2
Small ribosomal subunit protein uS5

1

2

High-throughput

0.508

High

875963

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

2

High-throughput

0.508

High

983975

ZBT16
Zinc finger and BTB domain-containing protein 16

1

2

High-throughput

0.508

High

1054081

DOCK7
Dedicator of cytokinesis protein 7

1

13

High-throughput

0.508

High

1054100

PHAX
Phosphorylated adapter RNA export protein

1

1

High-throughput

0.508

High

912813

TYB4
Thymosin beta-4

1

0

High-throughput

0.486

High

1054069

FAD1
FAD synthase

1

0

High-throughput

0.486

High

147159

FCHO1
F-BAR domain only protein 1

1

10

High-throughput

0.481

High

264308

GGYF1
GRB10-interacting GYF protein 1

1

11

Small-scale

0.481

High

1054060

GGYF2
GRB10-interacting GYF protein 2

1

20

Small-scale

0.481

High

162047

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

20

Small-scale

0.479

High

195434

DHX15
ATP-dependent RNA helicase DHX15

1

3

Small-scale

0.479

High

209985

PRC1
Protein regulator of cytokinesis 1

1

10

Small-scale

0.479

High

272134

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

10

Small-scale

0.479

High

308202

LC7L3
Luc7-like protein 3

1

3

Small-scale

0.479

High

321544

AP2A1
AP-2 complex subunit alpha-1

1

7

Small-scale

0.479

High

400310

RLA1
Large ribosomal subunit protein P1

1

2

Small-scale

0.479

High

418272

NPM
Nucleophosmin

1

6

Small-scale

0.479

High

504078

HSP7C
Heat shock cognate 71 kDa protein

1

18

Small-scale

0.479

High

508522

TOP1
DNA topoisomerase 1

1

1

Small-scale

0.479

High

559708

H12
Histone H1.2

1

5

Small-scale

0.479

High

618626

IF4B
Eukaryotic translation initiation factor 4B

1

12

Small-scale

0.479

High

643503

PTBP1
Polypyrimidine tract-binding protein 1

1

7

Small-scale

0.479

High

737801

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

15

Small-scale

0.479

High

739715

SRP14
Signal recognition particle 14 kDa protein

1

1

Small-scale

0.479

High

783032

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

3

Small-scale

0.479

High

802090

NOP2
Probable 28S rRNA

1

1

Small-scale

0.479

High

834744

RBP2
E3 SUMO-protein ligase RanBP2

1

8

Small-scale

0.479

High

852924

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

5

Small-scale

0.479

High

855477

MSH6
DNA mismatch repair protein Msh6

1

2

Small-scale

0.479

High

867702

SYRC
Arginine--tRNA ligase, cytoplasmic

1

2

Small-scale

0.479

High

958023

RBM10
RNA-binding protein 10

1

7

Small-scale

0.479

High

969693

KIF23
Kinesin-like protein KIF23

1

9

Small-scale

0.479

High

990444

CKAP4
Cytoskeleton-associated protein 4

1

14

Small-scale

0.479

High

1016573

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

1

Small-scale

0.479

High

1024012

ACACA
Acetyl-CoA carboxylase 1

1

8

Small-scale

0.479

High

1028907

SRSF6
Serine/arginine-rich splicing factor 6

1

14

Small-scale

0.479

High

1048060

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

Small-scale

0.479

High

1053851

CAPR1
Caprin-1

1

13

Small-scale

0.479

High

1054048

FAT1
Protocadherin Fat 1

1

8

Small-scale

0.479

High

1054049

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

13

Small-scale

0.479

High

1054050

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

7

Small-scale

0.479

High

1054051

NUMA1
Nuclear mitotic apparatus protein 1

1

13

Small-scale

0.479

High

1054057

RRP12
RRP12-like protein

1

1

Small-scale

0.479

High

1054061

LYRIC
Protein LYRIC

1

1

Small-scale

0.479

High

1054072

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

3

Small-scale

0.479

High

1054075

HDAC2
Histone deacetylase 2

1

11

Small-scale

0.479

High

1054078

LTV1
Protein LTV1 homolog

1

2

Small-scale

0.479

High

1054082

RBM14
RNA-binding protein 14

1

12

Small-scale

0.479

High

1054086

TCPH
T-complex protein 1 subunit eta

1

20

Small-scale

0.479

High

1054088

MBB1A
Myb-binding protein 1A

1

1

Small-scale

0.479

High

1054090

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

9

Small-scale

0.479

High

1054091

GNL3
Guanine nucleotide-binding protein-like 3

1

2

Small-scale

0.479

High

1054094

GTPB4
GTP-binding protein 4

1

5

Small-scale

0.479

High

1054095

DDX24
ATP-dependent RNA helicase DDX24

1

13

Small-scale

0.479

High

1054096

NAT10
RNA cytidine acetyltransferase

1

1

Small-scale

0.479

High

1054103

ABCF2
ATP-binding cassette sub-family F member 2

1

1

Small-scale

0.479

High

1054104

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1054105

PUF60
Poly(U)-binding-splicing factor PUF60

1

9

Small-scale

0.479

High

1054106

EI2BD
Translation initiation factor eIF2B subunit delta

1

1

Small-scale

0.479

High

1054108

TPX2
Targeting protein for Xklp2

1

5

Small-scale

0.479

High

1054111

G3BP2
Ras GTPase-activating protein-binding protein 2

1

10

Small-scale

0.479

High

1054114

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

2

Small-scale

0.479

High

794254

MSH2
DNA mismatch repair protein Msh2

1

1

High-throughput

0.464

High

1054053

SETB1
Histone-lysine N-methyltransferase SETDB1

1

7

High-throughput

0.464

High

1054109

KMT2B
Histone-lysine N-methyltransferase 2B

1

11

High-throughput

0.464

High

198624

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

Small-scale

0.458

High

390226

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.458

High

883992

GEMI4
Gem-associated protein 4

1

0

Small-scale

0.458

High

1054052

CND1
Condensin complex subunit 1

1

0

Small-scale

0.458

High

1054084

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

Small-scale

0.458

High

1054087

TCF25
Ribosome quality control complex subunit TCF25

1

0

Small-scale

0.458

High

236499

NEMF
Ribosome quality control complex subunit NEMF

1

4

High-throughput

0.445

High

721987

RFC4
Replication factor C subunit 4

1

1

Small-scale

0.437

High

722238

RFC1
Replication factor C subunit 1

1

2

Small-scale

0.437

High

972740

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

1

1

Small-scale

0.437

High

1054055

DDB1
DNA damage-binding protein 1

1

2

Small-scale

0.437

High

1054059

HP1B3
Heterochromatin protein 1-binding protein 3

1

1

Small-scale

0.437

High

1054119

TNPO3
Transportin-3

1

7

Small-scale

0.437

High

1054056

R39L5
Putative ribosomal protein eL39-like 5

1

2

High-throughput

0.407

High

1054063

CRERF
CREB3 regulatory factor

2

0

High-throughput

0.316

High

1054085

HTF4
Transcription factor 12

2

0

High-throughput

0.316

High

1054098

F124B
Protein FAM124B

2

0

High-throughput

0.316

High

199190

ZNHI1
Zinc finger HIT domain-containing protein 1

2

0

High-throughput

0.310

High

948247

RT34
Small ribosomal subunit protein mS34

2

0

High-throughput

0.298

High

1054073

RT27
Small ribosomal subunit protein mS27

2

0

High-throughput

0.298

High

505825

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.265

Low

118307

HAX1
HCLS1-associated protein X-1

1

0

Small-scale

0.264

Low

677964

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024