Protein: ZNRF2
E3 ubiquitin-protein ligase ZNRF2 (EC 2.3.2.27) (Protein Ells2) (RING finger protein 202) (RING-type E3 ubiquitin transferase ZNRF2) (Zinc/RING finger protein 2)

Gene: ZNRF2
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q8NHG8

Gene Ontology (top 5):
GO:0001650 - fibrillar center
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

896498

UBE2N
Ubiquitin-conjugating enzyme E2 N

6

20

Small-scale

0.946

High

849375

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

20

Small-scale

0.754

High

851850

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

20

Small-scale

0.754

High

895853

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.754

High

919793

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.754

High

476075

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

Small-scale

0.647

High

647125

1433T
14-3-3 protein theta

2

3

Small-scale

0.624

High

1033125

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

20

Small-scale

0.621

High

1245509

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

Small-scale

0.621

High

1245510

UBE2W
Ubiquitin-conjugating enzyme E2 W

1

20

Small-scale

0.621

High

1245511

UB2E2
Ubiquitin-conjugating enzyme E2 E2

1

20

Small-scale

0.621

High

1245515

AKTIP
AKT-interacting protein

1

20

Small-scale

0.621

High

1245516

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

20

Small-scale

0.621

High

1245518

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

High-throughput

0.621

High

1242069

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

1

1

Small-scale

0.618

High

166976

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

2

2

Small-scale

0.611

High

1240685

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.586

High

135470

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

0

Small-scale

0.537

High

787527

MTOR
Serine/threonine-protein kinase mTOR

1

0

Small-scale

0.537

High

257203

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

2

High-throughput

0.536

High

904889

1433G
14-3-3 protein gamma

1

3

High-throughput

0.536

High

982301

1433F
14-3-3 protein eta

1

3

High-throughput

0.536

High

1067448

EEA1
Early endosome antigen 1

1

1

High-throughput

0.536

High

1239486

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

1

2

High-throughput

0.536

High

1245517

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

2

High-throughput

0.536

High

502923

MYH3
Myosin-3

1

0

High-throughput

0.513

High

1161740

KLD10
Kelch domain-containing protein 10

1

0

High-throughput

0.513

High

1245508

ARHG2
Rho guanine nucleotide exchange factor 2

1

0

High-throughput

0.513

High

1245513

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

1245520

TLN1
Talin-1

1

0

High-throughput

0.513

High

393287

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

Small-scale

0.501

High

63860

CGB1
Choriogonadotropin subunit beta variant 1

1

0

High-throughput

0.493

High

215825

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

0

High-throughput

0.493

High

1237548

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

1

2

High-throughput

0.489

High

843469

AT1A2
Sodium/potassium-transporting ATPase subunit alpha-2

1

3

Small-scale

0.479

High

1126015

PP6R3
Serine/threonine-protein phosphatase 6 regulatory subunit 3

1

2

Small-scale

0.479

High

1229993

RPTOR
Regulatory-associated protein of mTOR

1

1

Small-scale

0.479

High

1245512

LST8
Target of rapamycin complex subunit LST8

1

1

Small-scale

0.479

High

163024

XPO1
Exportin-1

1

0

High-throughput

0.458

High

1151990

LTOR1
Ragulator complex protein LAMTOR1

1

0

Small-scale

0.458

High

1245514

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1245519

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

0

Small-scale

0.458

High

1202769

WDR5B
WD repeat-containing protein 5B

2

0

High-throughput

0.328

High

146724

NCKP5
Nck-associated protein 5

1

0

High-throughput

0.279

Low

1233780

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024