Protein: CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 3) (NLI-IF) (NLI-interacting factor 3) (Small C-terminal domain phosphatase 1) (SCP1) (Small CTD phosphatase 1)

Gene: CTDS1, CTDSP1
Organism: Homo sapiens
Interactions: 104
UniProt ID: Q9GZU7

Gene Ontology (top 5):
GO:0001933 - negative regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0006470 - protein dephosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

150005

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

3

7

High-throughput

0.861

High

171243

CTDSL
CTD small phosphatase-like protein

3

7

High-throughput

0.861

High

362104

MBP
Myelin basic protein

6

2

High-throughput

0.738

High

1305172

CDCA3
Cell division cycle-associated protein 3

9

3

High-throughput

0.691

High

933602

TBA4A
Tubulin alpha-4A chain

3

6

High-throughput

0.667

High

1175165

TBA1A
Tubulin alpha-1A chain

3

6

High-throughput

0.667

High

1326687

TBB1
Tubulin beta-1 chain

3

5

High-throughput

0.667

High

326774

SNAI1
Zinc finger protein SNAI1

2

17

Small-scale

0.653

High

1114224

TBB8
Tubulin beta-8 chain

2

4

High-throughput

0.611

High

231841

MABP1
Mitogen-activated protein kinase-binding protein 1

2

1

High-throughput

0.606

High

411847

LCK
Tyrosine-protein kinase Lck

2

1

High-throughput

0.606

High

791008

CDN2C
Cyclin-dependent kinase 4 inhibitor C

2

3

High-throughput

0.606

High

984022

ZBT16
Zinc finger and BTB domain-containing protein 16

2

13

High-throughput

0.606

High

993290

ACTN3
Alpha-actinin-3

2

1

High-throughput

0.606

High

915955

RHOB
Rho-related GTP-binding protein RhoB

2

8

High-throughput

0.584

High

133013

SDCB1
Syntenin-1

2

0

High-throughput

0.580

High

324606

BAG3
BAG family molecular chaperone regulator 3

2

0

High-throughput

0.580

High

655540

IP3KB
Inositol-trisphosphate 3-kinase B

2

0

High-throughput

0.580

High

914889

YPEL5
Protein yippee-like 5

2

0

High-throughput

0.580

High

1157494

FAP20
Fanconi anemia core complex-associated protein 20

2

0

High-throughput

0.580

High

1161290

MORN3
MORN repeat-containing protein 3

2

0

High-throughput

0.580

High

1192627

STRA8
Stimulated by retinoic acid gene 8 protein homolog

2

0

High-throughput

0.580

High

1262195

TEKT4
Tektin-4

2

0

High-throughput

0.580

High

1309173

F110A
Protein FAM110A

2

0

High-throughput

0.580

High

1314669

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.580

High

1326685

CSTFT
Cleavage stimulation factor subunit 2 tau variant

2

0

High-throughput

0.580

High

1326695

FANCL
E3 ubiquitin-protein ligase FANCL

2

0

High-throughput

0.580

High

1326697

WWOX
WW domain-containing oxidoreductase

2

0

High-throughput

0.580

High

1326689

UBP29
Ubiquitin carboxyl-terminal hydrolase 29

1

3

Small-scale

0.561

High

1149529

HEAT6
HEAT repeat-containing protein 6

2

1

High-throughput

0.558

High

427008

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

6

High-throughput

0.541

High

601587

FGFR2
Fibroblast growth factor receptor 2

1

8

High-throughput

0.541

High

986029

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

1

High-throughput

0.541

High

987288

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

10

High-throughput

0.541

High

1137947

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

3

High-throughput

0.541

High

1326701

PKHM1
Pleckstrin homology domain-containing family M member 1

1

1

High-throughput

0.541

High

163245

XPO1
Exportin-1

1

2

High-throughput

0.536

High

518478

ADT3
ADP/ATP translocase 3

1

4

High-throughput

0.536

High

530965

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

3

High-throughput

0.536

High

871960

AT12A
Potassium-transporting ATPase alpha chain 2

1

3

High-throughput

0.536

High

1309484

TBA1C
Tubulin alpha-1C chain

1

6

High-throughput

0.536

High

1326690

ABCB6
ATP-binding cassette sub-family B member 6

1

3

High-throughput

0.536

High

1326694

FANCI
Fanconi anemia group I protein

1

1

High-throughput

0.536

High

1326696

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

3

High-throughput

0.536

High

1242298

PNMA1
Paraneoplastic antigen Ma1

1

2

High-throughput

0.532

High

528184

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.513

High

572526

IBP3
Insulin-like growth factor-binding protein 3

1

0

High-throughput

0.513

High

729230

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

0

High-throughput

0.513

High

871066

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

0

High-throughput

0.513

High

881675

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.513

High

1326691

NOP10
H/ACA ribonucleoprotein complex subunit 3

1

0

High-throughput

0.513

High

1326693

CENPM
Centromere protein M

1

0

High-throughput

0.513

High

1326698

MO4L1
Mortality factor 4-like protein 1

1

0

High-throughput

0.513

High

1326699

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.513

High

625028

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

7

Small-scale

0.501

High

883195

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

4

High-throughput

0.494

High

1127825

LRC73
Leucine-rich repeat-containing protein 73

1

1

High-throughput

0.494

High

1205879

GPSM1
G-protein-signaling modulator 1

1

1

High-throughput

0.494

High

1231802

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

1

High-throughput

0.494

High

518201

ADT1
ADP/ATP translocase 1

1

4

High-throughput

0.489

High

1185040

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

2

High-throughput

0.489

High

1199760

GPAT4
Glycerol-3-phosphate acyltransferase 4

1

2

High-throughput

0.489

High

1223870

AN13A
Ankyrin repeat domain-containing protein 13A

1

5

High-throughput

0.489

High

1312392

TBCD
Tubulin-specific chaperone D

1

1

High-throughput

0.489

High

1326684

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.489

High

1326686

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.489

High

348912

RASN
GTPase NRas

1

3

High-throughput

0.479

High

349628

RASH
GTPase HRas

1

2

High-throughput

0.479

High

527777

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

545601

RAC2
Ras-related C3 botulinum toxin substrate 2

1

6

High-throughput

0.479

High

892581

RAC3
Ras-related C3 botulinum toxin substrate 3

1

7

High-throughput

0.479

High

894401

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.479

High

900874

RHOA
Transforming protein RhoA

1

8

High-throughput

0.479

High

925595

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

High-throughput

0.479

High

951312

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

1025072

REST
RE1-silencing transcription factor

1

3

Small-scale

0.479

High

1078653

SMAD2
Mothers against decapentaplegic homolog 2

1

6

Small-scale

0.479

High

1078756

SMAD1
Mothers against decapentaplegic homolog 1

1

6

Small-scale

0.479

High

1326688

RHOJ
Rho-related GTP-binding protein RhoJ

1

8

High-throughput

0.479

High

1089465

Q17RL8
HCG2004980, isoform CRA_e

1

3

High-throughput

0.470

High

1176208

PDZD4
PDZ domain-containing protein 4

1

3

High-throughput

0.439

High

1272160

OSTF1
Osteoclast-stimulating factor 1

1

3

High-throughput

0.439

High

120626

RHOD
Rho-related GTP-binding protein RhoD

1

9

High-throughput

0.437

High

350530

RASK
GTPase KRas

1

3

High-throughput

0.437

High

793461

MUC18
Cell surface glycoprotein MUC18

1

4

High-throughput

0.437

High

1326700

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.437

High

1167781

DUSTY
Dual serine/threonine and tyrosine protein kinase

3

0

High-throughput

0.347

High

1308668

F118B
Protein FAM118B

3

0

High-throughput

0.347

High

276606

TPC6A
Trafficking protein particle complex subunit 6A

2

0

High-throughput

0.316

High

863877

CRBA2
Beta-crystallin A2

2

0

High-throughput

0.316

High

1191299

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.316

High

1199965

NOXA1
NADPH oxidase activator 1

2

0

High-throughput

0.316

High

1252964

R3GEF
Guanine nucleotide exchange factor for Rab-3A

2

0

High-throughput

0.316

High

64559

ZSWM8
Zinc finger SWIM domain-containing protein 8

1

0

High-throughput

0.282

High

245410

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

882802

STX17
Syntaxin-17

1

0

High-throughput

0.279

Low

905488

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

0

High-throughput

0.279

Low

1109158

KRA61
Keratin-associated protein 6-1

1

0

High-throughput

0.279

Low

1139286

LYPL1
Lysophospholipase-like protein 1

1

0

High-throughput

0.279

Low

1139334

LIPK
Lipase member K

1

0

High-throughput

0.279

Low

1157927

FXL22
F-box and leucine-rich protein 22

1

0

High-throughput

0.279

Low

1260435

S20A1
Sodium-dependent phosphate transporter 1

1

0

High-throughput

0.279

Low

1295793

CH076
Uncharacterized protein C8orf76

1

0

High-throughput

0.279

Low

1326692

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024