Protein: SUFU
Suppressor of fused homolog (SUFUH)

Gene: SUFU
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q9UMX1

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001843 - neural tube closure
GO:0001947 - heart looping
GO:0003281 - ventricular septum development
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

436760

GLI1
Zinc finger protein GLI1

17

11

Small-scale

0.766

High

1293124

ZN764
Zinc finger protein 764

6

2

High-throughput

0.736

High

1313625

ZN747
Zinc finger protein 747

5

2

High-throughput

0.726

High

673642

MPIP3
M-phase inducer phosphatase 3

5

2

High-throughput

0.718

High

485150

GLI3
Transcriptional activator GLI3

4

11

Small-scale

0.697

High

485095

GLI2
Zinc finger protein GLI2

4

11

Small-scale

0.696

High

1243032

GLIS3
Zinc finger protein GLIS3

4

11

Small-scale

0.686

High

1347377

ZN446
Zinc finger protein 446

3

3

High-throughput

0.667

High

1252678

ZSC18
Zinc finger and SCAN domain-containing protein 18

3

3

High-throughput

0.665

High

1357357

SUFU
Suppressor of fused homolog

1

1

Small-scale

0.647

High

1354641

FXL17
F-box/LRR-repeat protein 17

3

0

Small-scale

0.645

High

1188097

HDX
Highly divergent homeobox

3

0

High-throughput

0.639

High

676722

AL1B1
Aldehyde dehydrogenase X, mitochondrial

3

0

High-throughput

0.638

High

1357358

LIPT
Lipoyl amidotransferase LIPT1, mitochondrial

3

0

High-throughput

0.638

High

1357361

NR2E1
Nuclear receptor subfamily 2 group E member 1

3

0

High-throughput

0.638

High

1357362

TTLL3
Tubulin monoglycylase TTLL3

3

0

High-throughput

0.638

High

1037544

BFSP2
Phakinin

4

1

High-throughput

0.638

High

1021746

NFAC3
Nuclear factor of activated T-cells, cytoplasmic 3

3

0

High-throughput

0.634

High

66717

ZN785
Zinc finger protein 785

2

1

High-throughput

0.628

High

885387

LOXL3
Lysyl oxidase homolog 3

2

1

High-throughput

0.611

High

1080643

ZIC1
Zinc finger protein ZIC 1

2

11

High-throughput

0.606

High

1120158

CRTC2
CREB-regulated transcription coactivator 2

2

1

High-throughput

0.606

High

1189678

K1C27
Keratin, type I cytoskeletal 27

2

1

High-throughput

0.606

High

1295452

LMBL3
Lethal(3)malignant brain tumor-like protein 3

2

2

High-throughput

0.606

High

1350202

ABI3
ABI gene family member 3

2

1

High-throughput

0.606

High

1342564

M1IP1
Mid1-interacting protein 1

2

0

High-throughput

0.606

High

230448

ZC3H1
Zinc finger C3H1 domain-containing protein

2

0

High-throughput

0.602

High

520187

BMP4
Bone morphogenetic protein 4

2

0

High-throughput

0.602

High

1087892

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

2

0

High-throughput

0.602

High

1191918

UBE3D
E3 ubiquitin-protein ligase E3D

2

0

High-throughput

0.602

High

1263055

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

2

0

High-throughput

0.602

High

154080

OVOL1
Putative transcription factor Ovo-like 1

2

0

High-throughput

0.595

High

1200817

ZBT46
Zinc finger and BTB domain-containing protein 46

2

0

High-throughput

0.585

High

161890

ZN263
Zinc finger protein 263

2

0

High-throughput

0.582

High

197857

CRX
Cone-rod homeobox protein

2

0

High-throughput

0.580

High

318905

K2C75
Keratin, type II cytoskeletal 75

2

0

High-throughput

0.580

High

843961

FXR1
RNA-binding protein FXR1

2

0

High-throughput

0.580

High

993649

TLE5
TLE family member 5

2

0

High-throughput

0.580

High

1000224

ZN763
Zinc finger protein 763

2

0

High-throughput

0.580

High

1240678

ZN114
Zinc finger protein 114

2

0

High-throughput

0.580

High

1344829

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.580

High

1357359

LZTS1
Leucine zipper putative tumor suppressor 1

2

0

High-throughput

0.580

High

1357360

ZN330
Zinc finger protein 330

2

0

High-throughput

0.580

High

1294886

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

1

Small-scale

0.578

High

1310480

RHG09
Rho GTPase-activating protein 9

2

1

High-throughput

0.571

High

1189840

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.558

High

154570

ZN213
Zinc finger protein 213

2

1

High-throughput

0.549

High

1219687

RHG12
Rho GTPase-activating protein 12

1

1

High-throughput

0.536

High

1070103

NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating]

1

0

High-throughput

0.518

High

1151302

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.515

High

1200932

Q86V38
Atrophin 1

1

1

High-throughput

0.515

High

352369

IGF2
Insulin-like growth factor II

1

0

High-throughput

0.513

High

610216

CCNO
Cyclin-O

1

0

High-throughput

0.513

High

782399

KDM5C
Lysine-specific demethylase 5C

1

0

High-throughput

0.513

High

1332770

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

258279

PX11A
Peroxisomal membrane protein 11A

1

0

High-throughput

0.493

High

1271977

KLK6
Kallikrein-6

1

0

High-throughput

0.493

High

1355941

MAGL2
MAGE-like protein 2

1

0

High-throughput

0.493

High

1350013

NYAP2
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2

1

1

High-throughput

0.489

High

838357

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.481

High

127894

SAP18
Histone deacetylase complex subunit SAP18

1

1

Small-scale

0.479

High

835563

GSK3A
Glycogen synthase kinase-3 alpha

1

1

High-throughput

0.479

High

836085

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

1169993

RHG36
Rho GTPase-activating protein 36

1

1

Small-scale

0.479

High

1254313

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

1291739

BICD1
Protein bicaudal D homolog 1

1

1

High-throughput

0.479

High

1345008

STK36
Serine/threonine-protein kinase 36

1

2

Small-scale

0.479

High

1191865

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

0

High-throughput

0.460

High

644351

TTP
mRNA decay activator protein ZFP36

1

0

High-throughput

0.458

High

890892

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

1042834

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1045150

RUNX3
Runt-related transcription factor 3

1

0

Small-scale

0.458

High

1168867

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

1306400

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

0

Small-scale

0.458

High

1355976

HOOK1
Protein Hook homolog 1

1

0

High-throughput

0.458

High

82350

B9A025
Lysyl oxidase homolog

1

1

High-throughput

0.407

High

1205647

F90A1
Protein FAM90A1

4

0

High-throughput

0.365

High

1287768

RCN3
Reticulocalbin-3

3

0

High-throughput

0.353

High

170575

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

3

0

High-throughput

0.347

High

305288

NXPH3
Neurexophilin-3

3

0

High-throughput

0.347

High

1093519

LRC36
Leucine-rich repeat-containing protein 36

2

0

High-throughput

0.328

High

1268034

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

2

0

High-throughput

0.328

High

1202281

LCA5
Lebercilin

2

0

High-throughput

0.316

High

1233517

STX19
Syntaxin-19

2

0

High-throughput

0.316

High

1292984

S41A3
Solute carrier family 41 member 3

2

0

High-throughput

0.316

High

1159757

ACKMT
ATP synthase subunit C lysine N-methyltransferase

1

0

High-throughput

0.279

Low

1166373

CF015
Uncharacterized protein C6orf15

1

0

High-throughput

0.279

Low

1290732

MYEOV
Myeloma-overexpressed gene protein

1

0

High-throughput

0.279

Low

135721

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.268

Low

1072851

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024