Protein: ACV1B
Activin receptor type-1B (EC 2.7.11.30) (Activin receptor type IB) (ACTR-IB) (Activin receptor-like kinase 4) (ALK-4) (Serine/threonine-protein kinase receptor R2) (SKR2)

Gene: ACV1B, ACVR1B
Organism: Homo sapiens
Interactions: 91
UniProt ID: P36896

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0001701 - in utero embryonic development
GO:0001942 - hair follicle development
GO:0004674 - protein serine/threonine kinase activity
GO:0004675 - transmembrane receptor protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

646019

AVR2A
Activin receptor type-2A

5

20

Small-scale

0.912

High

738449

AVR2B
Activin receptor type-2B

4

20

Small-scale

0.881

High

439882

INHBA
Inhibin beta A chain

4

20

Small-scale

0.878

High

738444

ACVR1
Activin receptor type-1

3

19

Small-scale

0.847

High

738439

FKB1A
Peptidyl-prolyl cis-trans isomerase FKBP1A

2

7

Small-scale

0.805

High

738434

TGFR2
TGF-beta receptor type-2

2

20

High-throughput

0.789

High

610690

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

1

2

High-throughput

0.698

High

537721

INSRR
Insulin receptor-related protein

1

20

High-throughput

0.691

High

738440

KC1G2
Casein kinase I isoform gamma-2

1

4

High-throughput

0.691

High

738457

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

1

High-throughput

0.691

High

738461

BTNL9
Butyrophilin-like protein 9

1

1

High-throughput

0.691

High

738467

P2RY8
P2Y purinoceptor 8

1

1

High-throughput

0.691

High

738472

ACV1C
Activin receptor type-1C

1

20

High-throughput

0.691

High

738473

PKR1
Prokineticin receptor 1

1

4

High-throughput

0.691

High

738498

STK36
Serine/threonine-protein kinase 36

1

7

High-throughput

0.691

High

738501

GPR83
G-protein coupled receptor 83

1

2

High-throughput

0.691

High

437952

HS90B
Heat shock protein HSP 90-beta

1

15

High-throughput

0.665

High

167337

SMAD7
Mothers against decapentaplegic homolog 7

3

20

Small-scale

0.657

High

738474

GPBAR
G-protein coupled bile acid receptor 1

1

0

High-throughput

0.656

High

738491

ZN644
Zinc finger protein 644

1

0

High-throughput

0.656

High

738486

NODAL
Nodal homolog

1

20

Small-scale

0.647

High

738456

CC50B
Cell cycle control protein 50B

2

3

High-throughput

0.628

High

738468

AGRG5
Adhesion G-protein coupled receptor G5

2

2

High-throughput

0.628

High

738481

MRAP2
Melanocortin-2 receptor accessory protein 2

2

5

High-throughput

0.628

High

738437

BAG6
Large proline-rich protein BAG6

1

1

High-throughput

0.621

High

738450

BMPR2
Bone morphogenetic protein receptor type-2

1

20

Small-scale

0.621

High

656354

DMB
HLA class II histocompatibility antigen, DM beta chain

1

1

High-throughput

0.618

High

384397

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.618

High

431602

HS90A
Heat shock protein HSP 90-alpha

1

15

High-throughput

0.618

High

436182

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

451818

INHBB
Inhibin beta B chain

1

20

Small-scale

0.618

High

738438

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

738463

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

738478

HAVR1
Hepatitis A virus cellular receptor 1

1

3

Small-scale

0.618

High

738490

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

199869

SPIT2
Kunitz-type protease inhibitor 2

2

3

High-throughput

0.611

High

526880

TDGF1
Protein Cripto

2

7

Small-scale

0.602

High

738495

SMUF1
E3 ubiquitin-protein ligase SMURF1

2

19

Small-scale

0.601

High

738454

SMAD2
Mothers against decapentaplegic homolog 2

2

20

Small-scale

0.595

High

239825

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

7

High-throughput

0.575

High

738448

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

3

High-throughput

0.575

High

738485

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

19

High-throughput

0.561

High

530236

ICAM2
Intercellular adhesion molecule 2

1

1

High-throughput

0.536

High

738458

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

1

High-throughput

0.536

High

738462

I20RB
Interleukin-20 receptor subunit beta

1

7

High-throughput

0.536

High

738470

RELL2
RELT-like protein 2

1

2

High-throughput

0.536

High

738471

RN149
E3 ubiquitin-protein ligase RNF149

1

12

High-throughput

0.536

High

738477

BSND
Barttin

1

1

High-throughput

0.536

High

738484

OPALI
Opalin

1

3

High-throughput

0.536

High

738494

CRLF2
Cytokine receptor-like factor 2

1

5

High-throughput

0.536

High

738500

CLDN1
Claudin domain-containing protein 1

1

1

High-throughput

0.536

High

738502

GPC5B
G-protein coupled receptor family C group 5 member B

1

1

High-throughput

0.536

High

738503

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

5

High-throughput

0.536

High

738460

AR26L
Putative ankyrin repeat domain-containing protein 26-like protein

1

4

High-throughput

0.514

High

738436

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

738487

TSNAX
Translin-associated protein X

1

0

High-throughput

0.513

High

738488

SYT11
Synaptotagmin-11

1

0

High-throughput

0.513

High

738445

BAMBI
BMP and activin membrane-bound inhibitor homolog

1

5

Small-scale

0.501

High

738480

OTUB1
Ubiquitin thioesterase OTUB1

1

4

Small-scale

0.501

High

738441

DLK1
Protein delta homolog 1

1

3

High-throughput

0.489

High

738452

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

2

High-throughput

0.489

High

738455

SGCA
Alpha-sarcoglycan

1

1

High-throughput

0.489

High

738466

T200A
Transmembrane protein 200A

1

2

High-throughput

0.489

High

738476

KCNE4
Potassium voltage-gated channel subfamily E member 4

1

1

High-throughput

0.489

High

738482

ZDH12
Palmitoyltransferase ZDHHC12

1

1

High-throughput

0.489

High

738492

MANS1
MANSC domain-containing protein 1

1

2

High-throughput

0.489

High

738496

TMM9B
Transmembrane protein 9B

1

3

High-throughput

0.489

High

587129

RXRA
Retinoic acid receptor RXR-alpha

1

1

High-throughput

0.481

High

123520

PGRC1
Membrane-associated progesterone receptor component 1

1

5

High-throughput

0.479

High

206940

SMAD6
Mothers against decapentaplegic homolog 6

1

20

Small-scale

0.479

High

240359

SNX2
Sorting nexin-2

1

8

Small-scale

0.479

High

738435

GRP75
Stress-70 protein, mitochondrial

1

2

High-throughput

0.479

High

738442

SMAD3
Mothers against decapentaplegic homolog 3

1

20

Small-scale

0.479

High

738443

XIAP
E3 ubiquitin-protein ligase XIAP

1

8

Small-scale

0.479

High

738447

SNX1
Sorting nexin-1

1

9

Small-scale

0.479

High

738453

T22D1
TSC22 domain family protein 1

1

6

Small-scale

0.479

High

738459

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

738464

ZFY16
Zinc finger FYVE domain-containing protein 16

1

2

Small-scale

0.479

High

738465

PEG10
Retrotransposon-derived protein PEG10

1

8

Small-scale

0.479

High

738469

IGSF1
Immunoglobulin superfamily member 1

1

7

Small-scale

0.479

High

738479

TSN17
Tetraspanin-17

1

4

High-throughput

0.479

High

738499

CC50A
Cell cycle control protein 50A

1

3

High-throughput

0.479

High

738451

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

3

High-throughput

0.445

High

738446

OS9
Protein OS-9

1

1

High-throughput

0.439

High

68226

HECA2
HEPACAM family member 2

1

3

High-throughput

0.437

High

237790

TSN3
Tetraspanin-3

1

4

High-throughput

0.437

High

738497

SAR1A
Small COPII coat GTPase SAR1A

1

4

High-throughput

0.437

High

738475

TM171
Transmembrane protein 171

1

0

High-throughput

0.279

Low

738489

VPS16
Vacuolar protein sorting-associated protein 16 homolog

1

0

High-throughput

0.279

Low

738493

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.279

Low

738483

ZDH15
Palmitoyltransferase ZDHHC15

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024