Protein: FRIZ2
Frizzled-2 (dFz2)

Gene: FRIZ2, fz2
Organism: Drosophila melanogaster
Interactions: 75
UniProt ID: Q9VVX3

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0007367 - segment polarity determination
GO:0007435 - salivary gland morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

484021

WNTG
Protein wingless

7

20

Small-scale

0.947

High

900681

DSH
Segment polarity protein dishevelled

2

20

Small-scale

0.775

High

703412

WNT2
Protein Wnt-2

2

20

Small-scale

0.713

High

1487507

FRIZ2
Frizzled-2

1

10

Small-scale

0.647

High

1487513

Q9W450
FI03335p

2

15

Small-scale

0.631

High

827129

WNT4
Protein Wnt-4

1

20

Small-scale

0.618

High

1174396

ROR1
Tyrosine-protein kinase transmembrane receptor Ror

1

2

Small-scale

0.618

High

911496

IMA
Importin subunit alpha

2

0

Small-scale

0.547

High

615121

PTC
Protein patched

1

4

High-throughput

0.508

High

1173126

Q24253
AP complex subunit beta

1

0

High-throughput

0.486

High

618806

DDX17
ATP-dependent RNA helicase p62

1

1

High-throughput

0.484

High

1230949

PTK7
Tyrosine-protein kinase-like otk

1

8

Small-scale

0.479

High

1263293

Q7JXW8
Off-track2

1

7

Small-scale

0.479

High

1476180

RENR
ATPase H(+)-transporting accessory protein 2

1

1

Small-scale

0.479

High

831934

PEP
Zinc finger protein on ecdysone puffs

1

0

High-throughput

0.464

High

1044936

NONA
Protein no-on-transient A

1

0

High-throughput

0.464

High

1175683

XPC
DNA repair protein complementing XP-C cells homolog

1

1

High-throughput

0.445

High

1303562

Q8IN25
Aminopeptidase

1

1

High-throughput

0.445

High

1484749

HERC2
Probable E3 ubiquitin-protein ligase HERC2

1

2

High-throughput

0.445

High

1266524

Q7K4L8
RNA helicase

1

1

High-throughput

0.442

High

1477828

Q9VIW0
Traffic jam, isoform B

1

0

High-throughput

0.438

High

1264349

Q7K0Q2
Importin beta11

1

6

Small-scale

0.437

High

467208

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.426

High

688436

SRR55
Serine-arginine protein 55

1

0

High-throughput

0.426

High

929435

FKB39
39 kDa FK506-binding nuclear protein

1

0

High-throughput

0.426

High

1064255

SQD
RNA-binding protein squid

1

0

High-throughput

0.426

High

1069615

Q0E8V8
MIP09469p

1

0

High-throughput

0.426

High

1176166

CAZ
RNA-binding protein cabeza

1

0

High-throughput

0.426

High

1268048

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

0

High-throughput

0.426

High

1275277

RNO
PHD finger protein rhinoceros

1

0

High-throughput

0.426

High

1304291

Q8INY3
FI02050p

1

0

High-throughput

0.426

High

1375057

U2AF1
Splicing factor U2af 38 kDa subunit

1

0

High-throughput

0.426

High

1470318

Q9VCE2
LD03179p

1

0

High-throughput

0.426

High

1484082

ATX7
Ataxin-7

1

0

High-throughput

0.426

High

1487512

Q9W3L1
RE04053p

1

0

High-throughput

0.426

High

1273632

VPS41
Vacuolar protein sorting-associated protein 41 homolog

1

2

High-throughput

0.407

High

1306593

Q8IRL9
DNA replication ATP-dependent helicase/nuclease

1

1

High-throughput

0.407

High

1445342

VATD2
V-type proton ATPase subunit D 2

1

1

High-throughput

0.407

High

1475452

Q9VH10
TBC1 domain family member 30

1

3

High-throughput

0.407

High

1230944

Q6AWJ8
LP19005p

1

5

High-throughput

0.381

High

58320

A1ZBJ8
FI19908p1

1

0

High-throughput

0.265

Low

1270125

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

0

High-throughput

0.253

Low

1487511

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.253

Low

1302745

Q8IGE8
RH36596p

1

0

High-throughput

0.238

Low

55312

A1Z9B0
FI19336p1

1

0

High-throughput

0.232

Low

72591

A9YH68
CG1716

1

0

High-throughput

0.232

Low

84782

B7Z0I2
Uncharacterized protein, isoform G

1

0

High-throughput

0.232

Low

264644

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.232

Low

559178

RS26
Small ribosomal subunit protein eS26

1

0

High-throughput

0.232

Low

607515

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.232

Low

710962

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.232

Low

1169461

Q1W9P9
Echinus splice form 3

1

0

High-throughput

0.232

Low

1264172

Q7K0E6
Aspartate--tRNA ligase, cytoplasmic

1

0

High-throughput

0.232

Low

1264358

Q7K0S5
UBX domain-containing protein 6

1

0

High-throughput

0.232

Low

1267037

Q7KA66
Serpin 43Aa

1

0

High-throughput

0.232

Low

1270014

Q7KVA7
Dynein heavy chain at 62B

1

0

High-throughput

0.232

Low

1305336

Q8IQC6
Small VCP interacting protein, isoform A

1

0

High-throughput

0.232

Low

1374617

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.232

Low

1377980

Q95SH2
Charged multivesicular body protein 1, isoform A

1

0

High-throughput

0.232

Low

1466423

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.232

Low

1467944

PTC71
Protein phosphatase PTC7 homolog fig

1

0

High-throughput

0.232

Low

1473329

ATD3A
ATPase family AAA domain-containing protein 3A homolog

1

0

High-throughput

0.232

Low

1473397

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

0

High-throughput

0.232

Low

1473776

RS5B
Small ribosomal subunit protein uS7B

1

0

High-throughput

0.232

Low

1478539

Q9VJK1
MIP03871p

1

0

High-throughput

0.232

Low

1482449

Q9VNA3
GH21273p

1

0

High-throughput

0.232

Low

1484709

Q9VR65
Uncharacterized protein

1

0

High-throughput

0.232

Low

1485773

SRP68
Signal recognition particle subunit SRP68

1

0

High-throughput

0.232

Low

1485954

Q9VT47
Uncharacterized protein, isoform D

1

0

High-throughput

0.232

Low

1486118

Q9VTH2
FI22313p1

1

0

High-throughput

0.232

Low

1487508

Q9VY49
LD24340p

1

0

High-throughput

0.232

Low

1487509

Q9VZ30
C2H2-type domain-containing protein

1

0

High-throughput

0.232

Low

1487510

Q9W179
Sterile20-like kinase, isoform B

1

0

High-throughput

0.232

Low

1487514

Q9W5D7
Uncharacterized protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025