Protein: FOLC
Folylpolyglutamate synthase, mitochondrial (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolylpolyglutamate synthase) (Tetrahydrofolate synthase)

Gene: FOLC, FPGS
Organism: Homo sapiens
Interactions: 26
UniProt ID: Q05932

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0004326 - tetrahydrofolylpolyglutamate synthase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

729214

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

3

1

High-throughput

0.656

High

985300

THEM4
Acyl-coenzyme A thioesterase THEM4

2

0

High-throughput

0.602

High

985303

NIT1
Deaminated glutathione amidase

2

0

High-throughput

0.602

High

254689

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

0

High-throughput

0.513

High

790244

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

0

High-throughput

0.513

High

985301

FAHD1
Oxaloacetate decarboxylase, mitochondrial

1

0

High-throughput

0.513

High

985304

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

985309

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.513

High

985312

AMACR
Alpha-methylacyl-CoA racemase

1

0

High-throughput

0.513

High

171982

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.489

High

227245

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

985299

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

985302

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

985306

BICD2
Protein bicaudal D homolog 2

1

0

High-throughput

0.458

High

985311

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

69727

B1AK13
Hydroxymethylglutaryl-CoA lyase, mitochondrial

1

1

High-throughput

0.445

High

527415

LAMP2
Lysosome-associated membrane glycoprotein 2

2

0

High-throughput

0.328

High

985307

LIPH
Lipase member H

2

0

High-throughput

0.318

High

985310

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

2

0

High-throughput

0.305

High

985305

TOIP2
Torsin-1A-interacting protein 2

2

0

High-throughput

0.288

High

985313

PLAK2
PALM2-AKAP2 fusion protein

2

0

High-throughput

0.288

High

351651

GLHA
Glycoprotein hormones alpha chain

1

0

High-throughput

0.279

Low

674019

V2R
Vasopressin V2 receptor

1

0

High-throughput

0.279

Low

825036

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

985298

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

0

High-throughput

0.279

Low

985308

DNAI2
Dynein axonemal intermediate chain 2

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024