Protein: PPTC7
Protein phosphatase PTC7 homolog (EC 3.1.3.16) (T-cell activation protein phosphatase 2C) (TA-PP2C) (T-cell activation protein phosphatase 2C-like)

Gene: PPTC7
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q8NI37

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005759 - mitochondrial matrix
GO:0010795 - regulation of ubiquinone biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1092065

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

5

1

High-throughput

0.717

High

1341188

TR61B
tRNA

4

0

High-throughput

0.664

High

1341185

TRM2B
tRNA

3

0

High-throughput

0.638

High

507289

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

3

High-throughput

0.628

High

1341179

PPTC7
Protein phosphatase PTC7 homolog

1

4

High-throughput

0.618

High

539370

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

2

0

High-throughput

0.602

High

1187365

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

2

0

High-throughput

0.602

High

1341181

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

2

0

High-throughput

0.602

High

1341196

ASF1B
Histone chaperone ASF1B

2

1

High-throughput

0.574

High

1341202

ASF1A
Histone chaperone ASF1A

2

1

High-throughput

0.574

High

1341183

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

2

2

High-throughput

0.553

High

1341200

XCT
Cystine/glutamate transporter

2

1

High-throughput

0.549

High

690713

AOFB
Amine oxidase [flavin-containing] B

1

1

High-throughput

0.536

High

992870

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.536

High

1312193

MIRO2
Mitochondrial Rho GTPase 2

1

2

High-throughput

0.536

High

1312321

MIRO1
Mitochondrial Rho GTPase 1

1

2

High-throughput

0.536

High

1341186

PARK7
Parkinson disease protein 7

1

1

High-throughput

0.536

High

1341195

DJC11
DnaJ homolog subfamily C member 11

1

3

High-throughput

0.536

High

451221

NFL
Neurofilament light polypeptide

1

1

High-throughput

0.515

High

348623

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.513

High

365429

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.513

High

553245

KCRB
Creatine kinase B-type

1

0

High-throughput

0.513

High

647606

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

High-throughput

0.513

High

648207

NDKB
Nucleoside diphosphate kinase B

1

0

High-throughput

0.513

High

697965

CALR
Calreticulin

1

0

High-throughput

0.513

High

1238218

GPAT2
Glycerol-3-phosphate acyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1341184

ACSF2
Medium-chain acyl-CoA ligase ACSF2, mitochondrial

1

0

High-throughput

0.513

High

1341189

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.513

High

1341191

TRABD
TraB domain-containing protein

1

0

High-throughput

0.513

High

1341192

ABCB6
ATP-binding cassette sub-family B member 6

1

0

High-throughput

0.513

High

1341194

PLCE
1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon

1

0

High-throughput

0.513

High

445223

S10A6
Protein S100-A6

1

3

High-throughput

0.489

High

481339

HMGB1
High mobility group protein B1

1

1

High-throughput

0.489

High

716324

PRDX6
Peroxiredoxin-6

1

1

High-throughput

0.489

High

730074

1433B
14-3-3 protein beta/alpha

1

3

High-throughput

0.489

High

1017042

H33
Histone H3.3

1

2

High-throughput

0.489

High

1066407

RBBP4
Histone-binding protein RBBP4

1

4

High-throughput

0.489

High

239380

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

1

High-throughput

0.479

High

1341182

SSH1
Protein phosphatase Slingshot homolog 1

1

2

High-throughput

0.479

High

109471

G5E9A7
DM1 locus, WD repeat containing

1

2

High-throughput

0.470

High

1058156

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1178963

SPKAP
A-kinase anchor protein SPHKAP

1

0

High-throughput

0.458

High

1341193

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1341197

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.458

High

1341203

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.458

High

653453

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.426

High

562251

LAMP2
Lysosome-associated membrane glycoprotein 2

2

0

High-throughput

0.328

High

749237

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1341180

F174A
Membrane protein FAM174A

2

0

High-throughput

0.328

High

1341187

LPAR4
Lysophosphatidic acid receptor 4

2

0

High-throughput

0.328

High

832753

BCL6
B-cell lymphoma 6 protein

2

0

High-throughput

0.316

High

1307579

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

123776

MYO1C
Unconventional myosin-Ic

1

0

High-throughput

0.279

Low

446447

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.279

Low

488517

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

High-throughput

0.279

Low

847786

SSRB
Translocon-associated protein subunit beta

1

0

High-throughput

0.279

Low

984207

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.279

Low

992616

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.279

Low

995446

TPM4
Tropomyosin alpha-4 chain

1

0

High-throughput

0.279

Low

1245887

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1292394

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.279

Low

1340025

GP150
Probable G-protein coupled receptor 150

1

0

High-throughput

0.279

Low

1341190

CSTL1
Cystatin-like 1

1

0

High-throughput

0.279

Low

1341198

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1341199

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low

1341201

PA2G4
Proliferation-associated protein 2G4

1

0

High-throughput

0.279

Low

1341204

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

1341205

HS3S4
Heparan sulfate glucosamine 3-O-sulfotransferase 4

1

0

High-throughput

0.279

Low

301580

WFS1
Wolframin

1

0

High-throughput

0.268

Low

1279651

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

980022

H4
Histone H4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025