Protein: AN13A
Ankyrin repeat domain-containing protein 13A (Protein KE03)

Gene: AN13A, ANKRD13A
Organism: Homo sapiens
Interactions: 159
UniProt ID: Q8IZ07

Gene Ontology (top 5):
GO:0002091 - negative regulation of receptor internalization
GO:0005737 - cytoplasm
GO:0005770 - late endosome
GO:0005886 - plasma membrane
GO:0048471 - perinuclear region of cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315860

KCIP2
A-type potassium channel modulatory protein KCNIP2

3

1

High-throughput

0.861

High

363548

EGFR
Epidermal growth factor receptor

3

3

Small-scale

0.827

High

539890

RALB
Ras-related protein Ral-B

2

10

High-throughput

0.811

High

1315875

KC1G3
Casein kinase I isoform gamma-3

2

12

High-throughput

0.811

High

1315851

ASB7
Ankyrin repeat and SOCS box protein 7

2

16

High-throughput

0.726

High

934846

TERA
Transitional endoplasmic reticulum ATPase

1

10

Small-scale

0.724

High

508265

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

5

11

Small-scale

0.710

High

539821

RALA
Ras-related protein Ral-A

1

10

High-throughput

0.691

High

978148

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.691

High

1244856

KCIP4
Kv channel-interacting protein 4

1

1

High-throughput

0.691

High

1155160

EREP1
Endosomal transmembrane epsin interactor 1

3

3

High-throughput

0.667

High

409592

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

0

High-throughput

0.656

High

987761

GRB2
Growth factor receptor-bound protein 2

1

2

Small-scale

0.647

High

1315857

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

10

Small-scale

0.647

High

931866

EPHA5
Ephrin type-A receptor 5

1

4

High-throughput

0.646

High

158579

CTDS2
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

4

5

High-throughput

0.630

High

181005

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

4

1

High-throughput

0.630

High

1010495

EREP3
Protein ENTREP3

4

3

High-throughput

0.630

High

1315614

IZUM1
Izumo sperm-egg fusion protein 1

2

1

High-throughput

0.628

High

1315859

ARHG4
Rho guanine nucleotide exchange factor 4

1

5

High-throughput

0.618

High

1163784

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

2

High-throughput

0.618

High

1254576

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.618

High

1315831

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

11

Small-scale

0.618

High

1315809

ARRD1
Arrestin domain-containing protein 1

2

4

High-throughput

0.611

High

907031

CCR6
C-C chemokine receptor type 6

2

3

High-throughput

0.601

High

1010071

DLK1
Protein delta homolog 1

2

11

High-throughput

0.601

High

1315823

STMN2
Stathmin-2

2

2

High-throughput

0.601

High

1315867

TRI10
Tripartite motif-containing protein 10

2

4

High-throughput

0.601

High

1132390

CASP8
Caspase-8

1

0

Small-scale

0.586

High

1315872

RNF11
RING finger protein 11

2

7

Small-scale

0.577

High

475994

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

3

High-throughput

0.575

High

962251

RHOA
Transforming protein RhoA

1

5

High-throughput

0.575

High

1315853

ZDH11
Palmitoyltransferase ZDHHC11

2

2

High-throughput

0.574

High

1109623

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

3

Small-scale

0.561

High

481031

DHPR
Dihydropteridine reductase

2

0

High-throughput

0.559

High

1315870

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

2

High-throughput

0.558

High

1315873

MFHA1
Malignant fibrous histiocytoma-amplified sequence 1

1

7

High-throughput

0.536

High

165984

FFAR1
Free fatty acid receptor 1

1

5

High-throughput

0.536

High

564039

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.536

High

669194

EDNRA
Endothelin-1 receptor

1

2

High-throughput

0.536

High

878050

AGRE5
Adhesion G protein-coupled receptor E5

1

1

High-throughput

0.536

High

946161

MLF1
Myeloid leukemia factor 1

1

3

High-throughput

0.536

High

956935

CXCR4
C-X-C chemokine receptor type 4

1

4

High-throughput

0.536

High

967317

TSN5
Tetraspanin-5

1

2

High-throughput

0.536

High

987104

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

7

High-throughput

0.536

High

1230699

TXND8
Thioredoxin domain-containing protein 8

1

2

High-throughput

0.536

High

1242853

S39A4
Zinc transporter ZIP4

1

1

High-throughput

0.536

High

1244258

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

1

High-throughput

0.536

High

1288401

TSN33
Tetraspanin-33

1

2

High-throughput

0.536

High

1315812

ARRD4
Arrestin domain-containing protein 4

1

4

High-throughput

0.536

High

1315813

ZNRF1
E3 ubiquitin-protein ligase ZNRF1

1

4

High-throughput

0.536

High

1315829

TSN17
Tetraspanin-17

1

2

High-throughput

0.536

High

1315833

M4A10
Membrane-spanning 4-domains subfamily A member 10

1

1

High-throughput

0.536

High

1315837

DESI2
Deubiquitinase DESI2

1

1

High-throughput

0.536

High

1315839

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

1

High-throughput

0.536

High

1315842

LRCC1
Leucine-rich repeat and coiled-coil domain-containing protein 1

1

3

High-throughput

0.536

High

1315854

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

3

High-throughput

0.536

High

1315874

KCMB2
Calcium-activated potassium channel subunit beta-2

1

1

High-throughput

0.536

High

1313753

S15A3
Solute carrier family 15 member 3

2

4

High-throughput

0.521

High

1315846

STMN4
Stathmin-4

1

2

High-throughput

0.515

High

1187490

AR13B
ADP-ribosylation factor-like protein 13B

1

2

High-throughput

0.514

High

291676

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

302026

NCTR1
Natural cytotoxicity triggering receptor 1

1

0

High-throughput

0.513

High

697421

DCK
Deoxycytidine kinase

1

0

High-throughput

0.513

High

935382

IOD3
Thyroxine 5-deiodinase

1

0

High-throughput

0.513

High

1134124

NTCP
Hepatic sodium/bile acid cotransporter

1

0

High-throughput

0.513

High

1315838

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.513

High

1315841

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

0

High-throughput

0.513

High

1315845

TOLIP
Toll-interacting protein

1

0

High-throughput

0.513

High

1315848

CYTM1
Cysteine-rich and transmembrane domain-containing protein 1

1

0

High-throughput

0.513

High

1315861

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.513

High

1315864

SL2A8
Solute carrier family 2, facilitated glucose transporter member 8

1

0

High-throughput

0.513

High

1110921

LAPM5
Lysosomal-associated transmembrane protein 5

1

1

High-throughput

0.508

High

1315836

SMAD5
Mothers against decapentaplegic homolog 5

1

3

High-throughput

0.508

High

178963

SCAM2
Secretory carrier-associated membrane protein 2

1

1

High-throughput

0.489

High

1207715

TMM31
Transmembrane protein 31

1

2

High-throughput

0.489

High

1233828

CV042
Uncharacterized protein C22orf42

1

1

High-throughput

0.489

High

1245310

WDR59
GATOR2 complex protein WDR59

1

5

High-throughput

0.489

High

1281708

B3GN8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8

1

1

High-throughput

0.489

High

1315821

DNJB3
DnaJ homolog subfamily B member 3

1

12

High-throughput

0.489

High

1315832

LRC3B
Leucine-rich repeat-containing protein 3B

1

1

High-throughput

0.489

High

1315835

METH
Methionine synthase

1

1

High-throughput

0.489

High

1315843

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

5

High-throughput

0.489

High

1315855

UBTD1
Ubiquitin domain-containing protein 1

1

1

High-throughput

0.489

High

1315865

FKB11
Peptidyl-prolyl cis-trans isomerase FKBP11

1

12

High-throughput

0.489

High

1315869

F153A
Protein FAM153A

1

3

High-throughput

0.489

High

1315825

WBP2
WW domain-binding protein 2

1

1

Small-scale

0.481

High

1315818

FBX25
F-box only protein 25

1

0

Small-scale

0.480

High

173048

XPO1
Exportin-1

1

12

High-throughput

0.479

High

242245

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

412236

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.479

High

639267

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

8

Small-scale

0.479

High

690294

STOM
Stomatin

1

1

High-throughput

0.479

High

1041163

CAV1
Caveolin-1

1

1

Small-scale

0.479

High

1096911

FADD
FAS-associated death domain protein

1

10

Small-scale

0.479

High

1101280

SLAF1
Signaling lymphocytic activation molecule

1

3

High-throughput

0.479

High

1142099

P2RY6
P2Y purinoceptor 6

1

5

High-throughput

0.479

High

1228992

RNF43
E3 ubiquitin-protein ligase RNF43

1

2

High-throughput

0.479

High

1315811

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.479

High

1315840

DUS23
Dual specificity protein phosphatase 23

1

14

High-throughput

0.479

High

1315868

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1249004

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

1315856

PLRKT
Plasminogen receptor

1

0

High-throughput

0.458

High

178323

NPC1
NPC intracellular cholesterol transporter 1

1

2

High-throughput

0.445

High

184019

S22A1
Solute carrier family 22 member 1

1

8

High-throughput

0.445

High

303255

S22A5
Organic cation/carnitine transporter 2

1

8

High-throughput

0.445

High

669345

ACKR3
Atypical chemokine receptor 3

1

4

High-throughput

0.445

High

722521

CTR1
High affinity cationic amino acid transporter 1

1

6

High-throughput

0.445

High

870260

S6A12
Sodium- and chloride-dependent betaine transporter

1

4

High-throughput

0.445

High

870377

S6A11
Sodium- and chloride-dependent GABA transporter 3

1

4

High-throughput

0.445

High

912693

CTR2
Cationic amino acid transporter 2

1

6

High-throughput

0.445

High

1273770

NIPA1
Magnesium transporter NIPA1

1

1

High-throughput

0.445

High

1274080

MOT14
Monocarboxylate transporter 14

1

2

High-throughput

0.445

High

1309752

CTL2
Choline transporter-like protein 2

1

2

High-throughput

0.445

High

1315808

CTL3
Choline transporter-like protein 3

1

2

High-throughput

0.445

High

1315810

S15A4
Solute carrier family 15 member 4

1

4

High-throughput

0.445

High

1315815

ZNT7
Zinc transporter 7

1

5

High-throughput

0.445

High

1315817

TBC15
TBC1 domain family member 15

1

1

High-throughput

0.445

High

1315822

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

1315826

ARRD3
Arrestin domain-containing protein 3

1

4

High-throughput

0.445

High

1315834

VPS35
Vacuolar protein sorting-associated protein 35

1

2

Small-scale

0.445

High

1315844

S22A4
Solute carrier family 22 member 4

1

8

High-throughput

0.445

High

1315858

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

4

High-throughput

0.445

High

1315866

STMN3
Stathmin-3

1

2

High-throughput

0.445

High

106243

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

912584

GDIR1
Rho GDP-dissociation inhibitor 1

1

3

High-throughput

0.437

High

1135220

Q149M6
Exophilin 5

1

1

High-throughput

0.437

High

1315847

UN93B
Protein unc-93 homolog B1

1

2

High-throughput

0.437

High

190428

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.426

High

219445

S26A4
Pendrin

1

0

High-throughput

0.426

High

845214

SATT
Neutral amino acid transporter A

1

0

High-throughput

0.426

High

1007878

X3CL1
Fractalkine

1

0

High-throughput

0.426

High

1238880

MFS12
Major facilitator superfamily domain-containing protein 12

1

0

High-throughput

0.426

High

1244098

TMM88
Transmembrane protein 88

1

0

High-throughput

0.426

High

1254181

MFSD6
Major facilitator superfamily domain-containing protein 6

1

0

High-throughput

0.426

High

505291

F153B
Protein FAM153B

1

3

High-throughput

0.407

High

1007445

S35B1
Solute carrier family 35 member B1

1

7

High-throughput

0.407

High

1238058

S18B1
MFS-type transporter SLC18B1

1

2

High-throughput

0.407

High

1308892

S22A9
Organic anion transporter 7

1

8

High-throughput

0.407

High

1315814

EXPH5
Exophilin-5

1

1

High-throughput

0.407

High

1315816

MFSD8
Major facilitator superfamily domain-containing protein 8

1

3

High-throughput

0.407

High

1315819

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

2

High-throughput

0.407

High

1315824

S35B4
Nucleotide sugar transporter SLC35B4

1

6

High-throughput

0.407

High

1315849

S35B3
Adenosine 3'-phospho 5'-phosphosulfate transporter 2

1

7

High-throughput

0.407

High

1315871

S35A3
UDP-N-acetylglucosamine transporter

1

4

High-throughput

0.407

High

1315820

TM171
Transmembrane protein 171

2

0

High-throughput

0.313

High

1187399

SHSL1
Protein shisa-like-1

1

0

High-throughput

0.279

Low

1219845

OBI1
ORC ubiquitin ligase 1

1

0

High-throughput

0.279

Low

1228545

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.279

Low

1278406

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.279

Low

1315827

HAUS1
HAUS augmin-like complex subunit 1

1

0

High-throughput

0.279

Low

1315828

PGAP3
GPI-specific phospholipase A2-like PGAP3

1

0

High-throughput

0.279

Low

1315852

HAUS4
HAUS augmin-like complex subunit 4

1

0

High-throughput

0.279

Low

1315862

T11L1
T-complex protein 11-like protein 1

1

0

High-throughput

0.279

Low

1315830

WBP1
WW domain-binding protein 1

1

0

High-throughput

0.249

Low

1315863

TMM51
Transmembrane protein 51

1

0

High-throughput

0.249

Low

1292388

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.232

Low

1313963

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1315850

MFSD1
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025