Protein: TRAF3
TNF receptor-associated factor 3 (EC 2.3.2.27) (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (RING-type E3 ubiquitin transferase TRAF3)

Gene: TRAF3
Organism: Mus musculus
Interactions: 100
UniProt ID: Q60803

Gene Ontology (top 5):
GO:0001817 - regulation of cytokine production
GO:0002224 - toll-like receptor signaling pathway
GO:0005164 - tumor necrosis factor receptor binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1141450

TBK1
Serine/threonine-protein kinase TBK1

7

20

Small-scale

0.736

High

1141429

MAVS
Mitochondrial antiviral-signaling protein

4

15

Small-scale

0.687

High

1141416

TCAM1
TIR domain-containing adapter molecule 1

4

12

Small-scale

0.686

High

607554

MYD88
Myeloid differentiation primary response protein MyD88

3

19

Small-scale

0.670

High

648958

TNR5
Tumor necrosis factor receptor superfamily member 5

3

20

Small-scale

0.656

High

1141406

DLG4
Disks large homolog 4

2

8

High-throughput

0.611

High

140028

BIRC3
Baculoviral IAP repeat-containing protein 3

2

20

Small-scale

0.595

High

936633

TANK
TRAF family member-associated NF-kappa-B activator

2

9

Small-scale

0.584

High

1141410

MYSM1
Deubiquitinase MYSM1

1

10

Small-scale

0.561

High

838553

TNR3
Tumor necrosis factor receptor superfamily member 3

1

20

Small-scale

0.536

High

70745

OTU7B
OTU domain-containing protein 7B

1

15

Small-scale

0.515

High

1141421

RNF41
E3 ubiquitin-protein ligase NRDP1

1

18

Small-scale

0.515

High

1141445

TLR4
Toll-like receptor 4

1

10

Small-scale

0.515

High

70740

KPRP
Keratinocyte proline-rich protein

1

2

Small-scale

0.479

High

101444

F8VPR5
histone acetyltransferase

1

7

Small-scale

0.479

High

101511

F8VQ72
Mitogen-activated protein kinase kinase kinase 1

1

18

Small-scale

0.479

High

193307

NUDC
Nuclear migration protein nudC

1

6

Small-scale

0.479

High

452185

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

5

Small-scale

0.479

High

665988

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

8

Small-scale

0.479

High

699618

RASK
GTPase KRas

1

15

Small-scale

0.479

High

729752

BTK
Tyrosine-protein kinase BTK

1

20

Small-scale

0.479

High

761814

TRAF2
TNF receptor-associated factor 2

1

17

Small-scale

0.479

High

808354

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

16

Small-scale

0.479

High

815731

KSYK
Tyrosine-protein kinase SYK

1

20

Small-scale

0.479

High

905341

1433G
14-3-3 protein gamma [Cleaved into: 14-3-3 protein gamma, N-terminally processed]

1

20

Small-scale

0.479

High

906263

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

6

Small-scale

0.479

High

934066

TBA1C
Tubulin alpha-1C chain

1

14

Small-scale

0.479

High

936206

TRAF5
TNF receptor-associated factor 5

1

17

Small-scale

0.479

High

936230

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

964091

CREB1
Cyclic AMP-responsive element-binding protein 1

1

6

Small-scale

0.479

High

1103180

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 homolog

1

6

Small-scale

0.479

High

1111982

NLRX1
NLR family member X1

1

20

Small-scale

0.479

High

1112151

ESYT2
Extended synaptotagmin-2

1

2

Small-scale

0.479

High

1112165

FUBP2
Far upstream element-binding protein 2

1

8

Small-scale

0.479

High

1112346

SC24A
Protein transport protein Sec24A

1

2

Small-scale

0.479

High

1112461

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

9

Small-scale

0.479

High

1137465

SAMC
Mitochondrial S-adenosylmethionine carrier protein

1

8

Small-scale

0.479

High

1141400

SC6A4
Sodium-dependent serotonin transporter

1

2

High-throughput

0.479

High

1141401

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

8

Small-scale

0.479

High

1141402

I17RA
Interleukin-17 receptor A

1

5

Small-scale

0.479

High

1141403

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

Small-scale

0.479

High

1141404

EWS
RNA-binding protein EWS

1

7

Small-scale

0.479

High

1141405

FXR1
RNA-binding protein FXR1

1

6

Small-scale

0.479

High

1141407

BIRC2
Baculoviral IAP repeat-containing protein 2

1

20

Small-scale

0.479

High

1141408

ASPP1
Apoptosis-stimulating of p53 protein 1

1

18

Small-scale

0.479

High

1141409

TIF1A
Transcription intermediary factor 1-alpha

1

18

Small-scale

0.479

High

1141411

SWP70
Switch-associated protein 70

1

10

Small-scale

0.479

High

1141415

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

8

Small-scale

0.479

High

1141417

PELO
Protein pelota homolog

1

1

Small-scale

0.479

High

1141419

Q80ZX0
SEC24 homolog B, COPII coat complex component

1

2

Small-scale

0.479

High

1141420

PCID2
PCI domain-containing protein 2

1

4

Small-scale

0.479

High

1141425

Q8CHD7
MKIAA0678 protein

1

10

Small-scale

0.479

High

1141426

ABLM1
Actin-binding LIM protein 1

1

19

Small-scale

0.479

High

1141427

CIKS
E3 ubiquitin ligase TRAF3IP2

1

12

Small-scale

0.479

High

1141430

ACLY
ATP-citrate synthase

1

2

Small-scale

0.479

High

1141432

STK38
Serine/threonine-protein kinase 38

1

13

Small-scale

0.479

High

1141434

ATAD3
ATPase family AAA domain-containing protein 3

1

5

Small-scale

0.479

High

1141435

RTN4
Reticulon-4

1

6

Small-scale

0.479

High

1141437

CHM4B
Charged multivesicular body protein 4b

1

5

Small-scale

0.479

High

1141438

TR13C
Tumor necrosis factor receptor superfamily member 13C

1

5

Small-scale

0.479

High

1141439

EF1G
Elongation factor 1-gamma

1

6

Small-scale

0.479

High

1141440

PGAM1
Phosphoglycerate mutase 1

1

5

Small-scale

0.479

High

1141442

ASC
Apoptosis-associated speck-like protein containing a CARD

1

9

Small-scale

0.479

High

1141447

CHIP
E3 ubiquitin-protein ligase CHIP

1

14

Small-scale

0.479

High

1141418

RT07
Small ribosomal subunit protein uS7m

1

0

Small-scale

0.458

High

1141424

MEF2C
Myocyte-specific enhancer factor 2C

1

0

Small-scale

0.458

High

1141433

WWOX
WW domain-containing oxidoreductase

1

0

Small-scale

0.458

High

1141436

GDIR1
Rho GDP-dissociation inhibitor 1

1

0

Small-scale

0.458

High

192587

TNR11
Tumor necrosis factor receptor superfamily member 11A

1

20

High-throughput

0.457

High

591448

TNR9
Tumor necrosis factor receptor superfamily member 9

1

20

Small-scale

0.457

High

812913

TNR4
Tumor necrosis factor receptor superfamily member 4

1

20

Small-scale

0.457

High

1141446

SRCN1
SRC kinase signaling inhibitor 1

1

3

High-throughput

0.445

High

69787

KRT36
Keratin, type I cuticular Ha6

1

20

Small-scale

0.437

High

102639

G3X928
Sec23 interacting protein

1

1

Small-scale

0.437

High

640187

EZRI
Ezrin

1

8

Small-scale

0.437

High

794350

MSH2
DNA mismatch repair protein Msh2

1

1

Small-scale

0.437

High

794625

H14
Histone H1.4

1

6

Small-scale

0.437

High

883707

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

20

Small-scale

0.437

High

903068

DCAF7
DDB1- and CUL4-associated factor 7

1

8

Small-scale

0.437

High

957023

KRT86
Keratin, type II cuticular Hb6

1

18

Small-scale

0.437

High

1111925

SMCA4
Transcription activator BRG1

1

3

Small-scale

0.437

High

1111997

Q3TMF4
GTPase NRas

1

14

Small-scale

0.437

High

1112036

Q3TRA8
Uncharacterized protein

1

4

Small-scale

0.437

High

1112375

HECD3
E3 ubiquitin-protein ligase HECTD3

1

20

Small-scale

0.437

High

1112686

AAK1
AP2-associated protein kinase 1

1

9

Small-scale

0.437

High

1141412

CE170
Centrosomal protein of 170 kDa

1

9

Small-scale

0.437

High

1141414

KRT87
Keratin, type II cuticular 87

1

18

Small-scale

0.437

High

1141422

RB39A
Ras-related protein Rab-39A

1

7

Small-scale

0.437

High

1141423

VCIP1
Deubiquitinating protein VCPIP1

1

1

Small-scale

0.437

High

1141441

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

Small-scale

0.437

High

1141443

KRT81
Keratin, type II cuticular Hb1

1

17

Small-scale

0.437

High

1141444

KC1E
Casein kinase I isoform epsilon

1

7

Small-scale

0.437

High

1141448

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

20

Small-scale

0.437

High

1141449

COR1B
Coronin-1B

1

8

Small-scale

0.437

High

1141451

Q9Z1A1
TFG protein

1

5

Small-scale

0.437

High

139063

SC22B
Vesicle-trafficking protein SEC22b

1

0

Small-scale

0.249

Low

1112102

TEX30
Testis-expressed protein 30

1

0

Small-scale

0.249

Low

1141413

KDSR
3-ketodihydrosphingosine reductase

1

0

Small-scale

0.249

Low

1141428

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

Small-scale

0.249

Low

1141431

S27A4
Long-chain fatty acid transport protein 4

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024