Protein: SYCY2
Syncytin-2 (Endogenous retrovirus group FRD member 1) (Envelope polyprotein) (HERV-FRD) (HERV-FRD_6p24.1 provirus ancestral Env polyprotein) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)]

Gene: SYCY2, ERVFRD-1
Organism: Homo sapiens
Interactions: 25
UniProt ID: P60508

Gene Ontology (top 5):
GO:0000768 - syncytium formation by plasma membrane fusion
GO:0005886 - plasma membrane
GO:0006949 - syncytium formation
GO:0007520 - myoblast fusion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

951934

SYCY2
Syncytin-2

1

1

Small-scale

0.647

High

719060

MIP
Lens fiber major intrinsic protein

2

0

High-throughput

0.580

High

951941

ZNT8
Proton-coupled zinc antiporter SLC30A8

2

0

High-throughput

0.580

High

951949

S41A2
Solute carrier family 41 member 2

2

0

High-throughput

0.580

High

951951

TMPS4
Transmembrane protease serine 4

2

0

High-throughput

0.580

High

951952

NINJ2
Ninjurin-2

2

0

High-throughput

0.580

High

328654

VAMP5
Vesicle-associated membrane protein 5

1

0

High-throughput

0.493

High

951935

PMP22
Peripheral myelin protein 22

1

0

High-throughput

0.493

High

951937

CCG1
Voltage-dependent calcium channel gamma-1 subunit

1

0

High-throughput

0.493

High

421827

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

951942

NLS1
Sodium-dependent lysophosphatidylcholine symporter 1

1

0

Small-scale

0.458

High

482236

PAEP
Glycodelin

2

0

High-throughput

0.316

High

951936

TAP1
Antigen peptide transporter 1

2

0

High-throughput

0.316

High

951939

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

0

High-throughput

0.316

High

951940

GPHB5
Glycoprotein hormone beta-5

2

0

High-throughput

0.316

High

951943

CC4L
C-C motif chemokine 4-like

2

0

High-throughput

0.316

High

951946

B2CL2
Bcl-2-like protein 2

2

0

High-throughput

0.316

High

951947

NXPE3
NXPE family member 3

2

0

High-throughput

0.316

High

951948

SC22A
Vesicle-trafficking protein SEC22a

2

0

High-throughput

0.316

High

899800

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.282

High

951938

ECHP
Peroxisomal bifunctional enzyme

1

0

High-throughput

0.268

Low

951944

GIMA1
GTPase IMAP family member 1

1

0

High-throughput

0.268

Low

951945

FAM3C
Protein FAM3C

1

0

High-throughput

0.268

Low

951950

TMM60
Transmembrane protein 60

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025