Protein: COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1 (NC1)]

Gene: COIA1, COL18A1
Organism: Homo sapiens
Interactions: 98
UniProt ID: P39060

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001525 - angiogenesis
GO:0001886 - endothelial cell morphogenesis
GO:0005576 - extracellular region
GO:0005581 - collagen trimer

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

760515

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

5

17

Small-scale

0.930

High

473745

C1T9A
Complement C1q and tumor necrosis factor-related protein 9A

3

20

High-throughput

0.861

High

626308

CO8A2
Collagen alpha-2(VIII) chain

3

19

High-throughput

0.847

High

70507

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

20

High-throughput

0.691

High

362515

C1QB
Complement C1q subcomponent subunit B

1

20

High-throughput

0.691

High

362584

C1QC
Complement C1q subcomponent subunit C

1

20

High-throughput

0.691

High

650067

CO8A1
Collagen alpha-1(VIII) chain

1

19

High-throughput

0.691

High

760531

ADIPO
Adiponectin

1

20

High-throughput

0.691

High

760557

C1QT1
Complement C1q tumor necrosis factor-related protein 1

1

20

High-throughput

0.691

High

760558

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

20

High-throughput

0.691

High

760565

COLQ
Acetylcholinesterase collagenic tail peptide

1

19

High-throughput

0.691

High

540418

MMP9
Matrix metalloproteinase-9

3

19

Small-scale

0.670

High

394246

A4
Amyloid-beta precursor protein

3

8

Small-scale

0.664

High

439231

MMP2
72 kDa type IV collagenase

3

19

Small-scale

0.662

High

358487

CO1A1
Collagen alpha-1(I) chain

1

19

Small-scale

0.647

High

358657

CO4A1

1

17

Small-scale

0.647

High

517929

CO6A1

1

17

Small-scale

0.647

High

760527

PTC1
Protein patched homolog 1

3

0

High-throughput

0.638

High

582109

NUCL
Nucleolin

2

0

Small-scale

0.632

High

362371

CRP

2

1

High-throughput

0.628

High

760524

PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

2

20

High-throughput

0.628

High

760543

C1QL4
Complement C1q-like protein 4

2

20

High-throughput

0.628

High

760520

DEF1
Neutrophil defensin 1

2

0

High-throughput

0.602

High

760560

SIAE
Sialate O-acetylesterase

2

0

High-throughput

0.585

High

403809

ITB1
Integrin beta-1

2

4

Small-scale

0.585

High

760534

Q4VAQ0
COL8A2 protein

1

20

High-throughput

0.575

High

760554

TRI11
E3 ubiquitin-protein ligase TRIM11

2

1

High-throughput

0.574

High

760522

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

8

Small-scale

0.552

High

760529

PCOC1
Procollagen C-endopeptidase enhancer 1

1

1

Small-scale

0.536

High

180009

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

6

High-throughput

0.536

High

760564

FBX2
F-box only protein 2

1

2

High-throughput

0.536

High

237034

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

20

High-throughput

0.536

High

486235

CCL3
C-C motif chemokine 3

1

4

High-throughput

0.536

High

532070

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

6

High-throughput

0.536

High

561730

CL3L1
C-C motif chemokine 3-like 1

1

4

High-throughput

0.536

High

760519

MFAP4
Microfibril-associated glycoprotein 4

1

1

High-throughput

0.536

High

760536

LAIR2
Leukocyte-associated immunoglobulin-like receptor 2

1

14

High-throughput

0.536

High

760544

SFPA2
Pulmonary surfactant-associated protein A2

1

17

High-throughput

0.536

High

760545

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

760546

GT252
Procollagen galactosyltransferase 2

1

20

High-throughput

0.536

High

760550

CC4L
C-C motif chemokine 4-like

1

4

High-throughput

0.536

High

760563

DNJB9
DnaJ homolog subfamily B member 9

1

2

High-throughput

0.536

High

441816

FGF4
Fibroblast growth factor 4

1

0

High-throughput

0.513

High

474701

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

532906

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.513

High

760523

IL5RA
Interleukin-5 receptor subunit alpha

1

0

High-throughput

0.513

High

760525

SG2A2
Mammaglobin-A

1

0

High-throughput

0.513

High

760526

OS9
Protein OS-9

1

0

High-throughput

0.513

High

760551

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.513

High

760556

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.513

High

760561

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

419169

ITAV
Integrin alpha-V

1

7

Small-scale

0.501

High

434625

TSP1
Thrombospondin-1

1

8

Small-scale

0.501

High

451073

SPRC
SPARC

1

5

Small-scale

0.501

High

528204

CCL2
C-C motif chemokine 2

1

4

Small-scale

0.501

High

535722

LYAM1
L-selectin

1

1

Small-scale

0.501

High

555714

LYAM3
P-selectin

1

2

Small-scale

0.501

High

601628

PGS1
Biglycan

1

5

Small-scale

0.501

High

602808

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

4

Small-scale

0.501

High

631054

LAMA1
Laminin subunit alpha-1

1

5

Small-scale

0.501

High

729620

VGFR2
Vascular endothelial growth factor receptor 2

1

2

Small-scale

0.501

High

557056

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.489

High

205125

TGON2
Trans-Golgi network integral membrane protein 2

1

8

High-throughput

0.479

High

346118

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

373812

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

501781

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

726629

FUS
RNA-binding protein FUS

1

2

High-throughput

0.479

High

760516

YAP1
Transcriptional coactivator YAP1

1

1

Small-scale

0.479

High

760518

MFAP2
Microfibrillar-associated protein 2

1

1

Small-scale

0.479

High

760539

OLFM4
Olfactomedin-4

1

2

High-throughput

0.479

High

760542

TMM25
Transmembrane protein 25

1

1

High-throughput

0.479

High

760532

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

760549

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

760552

LIPH
Lipase member H

1

0

High-throughput

0.458

High

760553

OPTN
Optineurin

1

0

High-throughput

0.458

High

760555

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

0

High-throughput

0.458

High

760559

ACE2
Angiotensin-converting enzyme 2

1

0

Small-scale

0.458

High

443049

ITA5
Integrin alpha-5

1

7

Small-scale

0.445

High

496471

TAU
Microtubule-associated protein tau

1

2

High-throughput

0.445

High

325647

LATS1
Serine/threonine-protein kinase LATS1

1

3

High-throughput

0.437

High

760540

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

760562

FBX6
F-box only protein 6

1

2

High-throughput

0.437

High

760533

TAZ
Tafazzin

3

0

High-throughput

0.347

High

451206

TPM1
Tropomyosin alpha-1 chain

2

0

Small-scale

0.322

High

369117

ESR1
Estrogen receptor

2

0

High-throughput

0.298

High

398500

PPB1
Alkaline phosphatase, placental type

1

0

High-throughput

0.279

Low

760530

EPHA7
Ephrin type-A receptor 7

1

0

High-throughput

0.279

Low

760537

IFIX
Pyrin and HIN domain-containing protein 1

1

0

High-throughput

0.279

Low

760541

TCPR1
Tectonin beta-propeller repeat-containing protein 1

1

0

High-throughput

0.279

Low

760548

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.279

Low

760528

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.251

Low

613940

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.249

Low

760517

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.249

Low

760521

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

760538

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

760535

LITD1
LINE-1 type transposase domain-containing protein 1

1

0

High-throughput

0.232

Low

760547

AHI1
Jouberin

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024