Protein: Q22174
Tr-type G domain-containing protein

Gene: Q22174, slfl-5
Organism: Caenorhabditis elegans
Interactions: 101
UniProt ID: Q22174

Gene Ontology (top 5):
GO:0003746 - translation elongation factor activity
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0006414 - translational elongation
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1170677

Q22174
Tr-type G domain-containing protein

2

14

High-throughput

0.826

High

916459

EF1A
Elongation factor 1-alpha

1

9

High-throughput

0.698

High

837938

REI1
Guanine nucleotide exchange factor rei-1

2

0

High-throughput

0.613

High

1169782

Q20476
BTB domain-containing protein

2

4

High-throughput

0.584

High

1169894

TRA4
Zinc finger protein tra-4

2

4

High-throughput

0.584

High

1170685

Q8I7L5
LIN-24

2

1

High-throughput

0.533

High

115236

H2KYP1
LIN-24

2

1

High-throughput

0.533

High

195877

O16997
PSP proline-rich domain-containing protein

1

1

High-throughput

0.532

High

144652

O01482
RING-type domain-containing protein

1

10

High-throughput

0.494

High

145373

O01961
C2H2-type domain-containing protein

1

1

High-throughput

0.494

High

195323

FIGL1
Fidgetin-like protein 1

1

9

High-throughput

0.494

High

195883

O17005
Large ribosomal subunit protein uL4m

1

4

High-throughput

0.494

High

233610

O44821
Ubiquitin-like domain-containing protein

1

11

High-throughput

0.494

High

233966

NH111
Nuclear hormone receptor family member nhr-111

1

18

High-throughput

0.494

High

759702

EI2BA
Translation initiation factor eIF2B subunit alpha

1

2

High-throughput

0.494

High

759733

NCL1
B-box type zinc finger protein ncl-1

1

12

High-throughput

0.494

High

773411

AP1M
AP-1 complex subunit mu-1-I

1

7

High-throughput

0.494

High

870592

RL23
Large ribosomal subunit protein uL14

1

2

High-throughput

0.494

High

898275

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.494

High

1019185

P91563
BTB domain-containing protein

1

10

High-throughput

0.494

High

1043389

SPK1
Serine/threonine-protein kinase spk-1

1

11

High-throughput

0.494

High

1164648

CWC22
Pre-mRNA-splicing factor CWC22 homolog

1

1

High-throughput

0.494

High

1165037

Q17746
ZZ-type domain-containing protein

1

4

High-throughput

0.494

High

1165880

Q18239
DiSHevelled related

1

9

High-throughput

0.494

High

1165972

Q18318
RRM domain-containing protein

1

10

High-throughput

0.494

High

1166212

FAM50
Protein FAM50 homolog

1

1

High-throughput

0.494

High

1166253

Q18776
BTB domain-containing protein

1

9

High-throughput

0.494

High

1166375

Q18986
BTB domain-containing protein

1

10

High-throughput

0.494

High

1166872

Q19764
Flocculation protein FLO11

1

4

High-throughput

0.494

High

1169762

Q20398
PDZ domain-containing protein

1

2

High-throughput

0.494

High

1170009

Q20950
Peptidase C1A papain C-terminal domain-containing protein

1

2

High-throughput

0.494

High

1170192

NFIL3
Transcription factor atf-2

1

7

High-throughput

0.494

High

1170500

VATL1
V-type proton ATPase 16 kDa proteolipid subunit c 1

1

1

High-throughput

0.494

High

1170679

Q22387
Centrosomal protein of 162 kDa

1

1

High-throughput

0.494

High

1170680

MIG15
Serine/threonine-protein kinase mig-15

1

9

High-throughput

0.494

High

1170690

Q95X87
RING-type domain-containing protein

1

8

High-throughput

0.494

High

1170694

Q9N3Z0
ZZ-type domain-containing protein

1

4

High-throughput

0.494

High

1170699

Q9NES7
Histidine-rich glycoprotein-like

1

2

High-throughput

0.494

High

1170704

DTN1
Dystrobrevin-1

1

3

High-throughput

0.494

High

1019822

P92004
Interferon regulatory factor 2-binding protein 1 & 2 zinc finger domain-containing protein

1

1

High-throughput

0.451

High

1165180

Q17940
DUF3501 family protein

1

1

High-throughput

0.451

High

1170678

MIG5
Segment polarity protein dishevelled homolog mig-5

1

10

High-throughput

0.451

High

1170686

Q8IAA7
ING domain-containing protein

1

1

High-throughput

0.451

High

1170696

Q9N5S8
Phospholipid/glycerol acyltransferase domain-containing protein

1

2

High-throughput

0.451

High

63082

A5A8Q6
C2H2-type domain-containing protein

1

2

High-throughput

0.439

High

73526

B2D6P5
Interferon regulatory factor 2-binding protein 1 & 2 zinc finger domain-containing protein

1

1

High-throughput

0.439

High

94646

D7SFN2
DUF3501 family protein

1

1

High-throughput

0.439

High

114049

G5EGR4
Girdin

1

2

High-throughput

0.439

High

115283

H2KYW2
NeurABin

1

1

High-throughput

0.439

High

115365

H2KZ17
DiSHevelled related

1

8

High-throughput

0.439

High

115791

H2L057
PHD-type domain-containing protein

1

1

High-throughput

0.439

High

1170684

Q86PI8
Nuclear receptor NHR-114

1

11

High-throughput

0.439

High

1170697

Q9N5S9
Phospholipid/glycerol acyltransferase domain-containing protein

1

2

High-throughput

0.439

High

112643

NH114
Nuclear hormone receptor 114

1

14

High-throughput

0.417

High

115101

H2KYD4
C2H2-type domain-containing protein

1

2

High-throughput

0.417

High

115165

H2KYH8
MADF domain-containing protein

1

1

High-throughput

0.417

High

115277

H2KYW1
Neurabin-1

1

7

High-throughput

0.417

High

1170687

Q8MQE8
MADF domain-containing protein

1

1

High-throughput

0.417

High

145119

O01796
LisH domain-containing protein

2

0

High-throughput

0.334

High

1170702

Q9U2E9
Nuclear receptor domain-containing protein

2

0

High-throughput

0.334

High

1170683

Q86D10
SPX domain-containing protein

1

0

High-throughput

0.292

High

1170689

GPR1
G-protein regulator 1

1

0

High-throughput

0.292

High

111323

G5ED20
RING-type domain-containing protein

1

0

High-throughput

0.282

High

113716

BRC2
DNA repair protein brc-2

1

0

High-throughput

0.282

High

113724

FAT2
Delta(12) fatty acid desaturase fat-2

1

0

High-throughput

0.282

High

144692

O01489
CCHC-type domain-containing protein

1

0

High-throughput

0.282

High

145319

O01917
Deltamethrin resistance protein prag01 domain-containing protein

1

0

High-throughput

0.282

High

196686

O18015
Ground-like domain-containing protein

1

0

High-throughput

0.282

High

196916

O18267
CCHC-type domain-containing protein

1

0

High-throughput

0.282

High

264361

O62505
LisH domain-containing protein

1

0

High-throughput

0.282

High

522561

MYSP
Paramyosin

1

0

High-throughput

0.282

High

759213

YLU3
Uncharacterized protein F10E9.3

1

0

High-throughput

0.282

High

759263

ESS2
Splicing factor ESS-2

1

0

High-throughput

0.282

High

759657

TF2H2
General transcription factor IIH subunit 2

1

0

High-throughput

0.282

High

759742

SOR1
Sop-2-related protein 1

1

0

High-throughput

0.282

High

853184

ZTF17
Zinc finger transcription factor family protein 17

1

0

High-throughput

0.282

High

939601

ASP3
Aspartic protease 3

1

0

High-throughput

0.282

High

1165016

Q17732
SH2 domain-containing protein

1

0

High-throughput

0.282

High

1165647

Q18043
Annexin A7

1

0

High-throughput

0.282

High

1166100

Q18535
Proline-rich protein PRCC

1

0

High-throughput

0.282

High

1166330

CEBP1
CCAAT/enhancer-binding protein homolog 1

1

0

High-throughput

0.282

High

1166352

SPCS
O-phosphoseryl-tRNA(Sec) selenium transferase

1

0

High-throughput

0.282

High

1169774

ATF6H
Transcription factor atf-6 homolog

1

0

High-throughput

0.282

High

1169872

Q20682
SPK domain-containing protein

1

0

High-throughput

0.282

High

1169941

Q20759
GDP/GTP exchange factor Sec2 N-terminal domain-containing protein

1

0

High-throughput

0.282

High

1170000

Q20936
Activated in Blocked Unfolded protein response

1

0

High-throughput

0.282

High

1170075

Q21088
GEX Interacting protein

1

0

High-throughput

0.282

High

1170681

Q23389
Uncharacterized protein

1

0

High-throughput

0.282

High

1170682

Q23664
C4H2-type domain-containing protein

1

0

High-throughput

0.282

High

1170688

Q93831
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.282

High

1170691

Q95ZV8
Nuclear transcription factor Y subunit

1

0

High-throughput

0.282

High

1170692

Q9GUC8
IBR domain-containing protein

1

0

High-throughput

0.282

High

1170693

Q9GYG1
C2H2-type domain-containing protein

1

0

High-throughput

0.282

High

1170695

Q9N4Z2
Nbl1_Borealin_N domain-containing protein

1

0

High-throughput

0.282

High

1170698

Q9NAJ7
SMN domain-containing protein

1

0

High-throughput

0.282

High

1170700

Q9TZ50
CCDC92/74 N-terminal domain-containing protein

1

0

High-throughput

0.282

High

1170701

Q9TZ84
Ubiquitin-like domain-containing protein

1

0

High-throughput

0.282

High

1019424

LST1
Lateral signaling target 1 protein

1

0

High-throughput

0.257

Low

1170703

Q9U2G8
SPK domain-containing protein

1

0

High-throughput

0.257

Low

94649

D7SFQ3
ANK_REP_REGION domain-containing protein

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025