Protein: SOX6
Transcription factor SOX-6

Gene: SOX6
Organism: Homo sapiens
Interactions: 150
UniProt ID: P35712

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001217 - DNA-binding transcription repressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

727705

SOX5
Transcription factor SOX-5

2

17

High-throughput

0.811

High

727941

SOX13
Transcription factor SOX-13

2

16

High-throughput

0.789

High

716823

CTNB1
Catenin beta-1

1

20

Small-scale

0.724

High

727836

SOX2
Transcription factor SOX-2

1

18

High-throughput

0.691

High

727847

TFAM
Transcription factor A, mitochondrial

1

18

High-throughput

0.646

High

727840

CTBP2
C-terminal-binding protein 2

2

12

Small-scale

0.620

High

540798

PO2F1
POU domain, class 2, transcription factor 1

1

20

High-throughput

0.618

High

727910

CIC
Protein capicua homolog

1

17

High-throughput

0.618

High

727930

HM20A
High mobility group protein 20A

1

20

High-throughput

0.618

High

727933

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

20

High-throughput

0.618

High

727845

UBC9
SUMO-conjugating enzyme UBC9

2

11

Small-scale

0.595

High

443140

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.578

High

727867

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

14

Small-scale

0.573

High

727863

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.561

High

507380

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.541

High

727911

ZN184
Zinc finger protein 184

1

2

High-throughput

0.541

High

727852

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

6

High-throughput

0.536

High

135088

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.515

High

564819

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.515

High

727855

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.515

High

174010

SHOX
Short stature homeobox protein

1

20

Small-scale

0.506

High

727913

CENPK
Centromere protein K

1

0

Small-scale

0.504

High

727480

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.501

High

727871

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.501

High

128048

IF2B3
Insulin-like growth factor 2 mRNA-binding protein 3

1

16

High-throughput

0.500

High

444089

RS17
Small ribosomal subunit protein eS17

1

3

High-throughput

0.500

High

718554

PHB1
Prohibitin 1

1

2

High-throughput

0.500

High

727837

PRC2A
Protein PRRC2A

1

20

High-throughput

0.500

High

727838

EMD
Emerin

1

3

High-throughput

0.500

High

727843

RS13
Small ribosomal subunit protein uS15

1

4

High-throughput

0.500

High

727844

RS11
Small ribosomal subunit protein uS17

1

4

High-throughput

0.500

High

727857

ILF2
Interleukin enhancer-binding factor 2

1

12

High-throughput

0.500

High

727859

G3BP1
Ras GTPase-activating protein-binding protein 1

1

6

High-throughput

0.500

High

727864

CIRBP
Cold-inducible RNA-binding protein

1

12

High-throughput

0.500

High

727866

CAPR1
Caprin-1

1

7

High-throughput

0.500

High

727868

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

12

High-throughput

0.500

High

727884

DHX30
ATP-dependent RNA helicase DHX30

1

13

High-throughput

0.500

High

727886

PABP2
Polyadenylate-binding protein 2

1

14

High-throughput

0.500

High

727894

CCAR2
Cell cycle and apoptosis regulator protein 2

1

7

High-throughput

0.500

High

727895

LS14A
Protein LSM14 homolog A

1

20

High-throughput

0.500

High

727903

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.500

High

727905

RBM33
RNA-binding protein 33

1

20

High-throughput

0.500

High

727916

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

19

High-throughput

0.500

High

727918

PDIP3
Polymerase delta-interacting protein 3

1

7

High-throughput

0.500

High

727919

XRN2
5'-3' exoribonuclease 2

1

3

High-throughput

0.500

High

727932

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

14

High-throughput

0.500

High

727949

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

5

High-throughput

0.489

High

727846

NOP14
Nucleolar protein 14

1

0

High-throughput

0.479

High

62890

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

4

High-throughput

0.479

High

65016

SOBP
Sine oculis-binding protein homolog

1

20

High-throughput

0.479

High

124172

TAF4
Transcription initiation factor TFIID subunit 4

1

16

Small-scale

0.479

High

164194

ZN609
Zinc finger protein 609

1

19

High-throughput

0.479

High

177214

HDAC3
Histone deacetylase 3

1

20

High-throughput

0.479

High

232023

KDM1A
Lysine-specific histone demethylase 1A

1

17

High-throughput

0.479

High

245570

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

20

High-throughput

0.479

High

260362

ZN217
Zinc finger protein 217

1

8

High-throughput

0.479

High

261422

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

277960

PIAS1
E3 SUMO-protein ligase PIAS1

1

11

High-throughput

0.479

High

473480

ATX1L
Ataxin-1-like

1

13

High-throughput

0.479

High

525288

NR2C1
Nuclear receptor subfamily 2 group C member 1

1

20

High-throughput

0.479

High

649051

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

18

High-throughput

0.479

High

727835

CUX1
Homeobox protein cut-like 1

1

20

High-throughput

0.479

High

727839

HIRA
Protein HIRA

1

20

High-throughput

0.479

High

727841

SUMO2
Small ubiquitin-related modifier 2

1

9

High-throughput

0.479

High

727842

DCAF7
DDB1- and CUL4-associated factor 7

1

20

High-throughput

0.479

High

727848

SATB1
DNA-binding protein SATB1

1

13

High-throughput

0.479

High

727849

MECOM
Histone-lysine N-methyltransferase MECOM

1

13

High-throughput

0.479

High

727850

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

727851

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

727853

RING1
E3 ubiquitin-protein ligase RING1

1

20

High-throughput

0.479

High

727856

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

20

High-throughput

0.479

High

727858

FOXC1
Forkhead box protein C1

1

20

High-throughput

0.479

High

727860

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.479

High

727861

PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2

1

5

High-throughput

0.479

High

727862

CTBP1
C-terminal-binding protein 1

1

12

High-throughput

0.479

High

727870

MEF2D
Myocyte-specific enhancer factor 2D

1

5

High-throughput

0.479

High

727872

NCOA2
Nuclear receptor coactivator 2

1

20

High-throughput

0.479

High

727873

ZFHX3
Zinc finger homeobox protein 3

1

16

High-throughput

0.479

High

727874

H31T
Histone H3.1t

1

20

High-throughput

0.479

High

727876

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.479

High

727877

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

9

High-throughput

0.479

High

727878

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

13

High-throughput

0.479

High

727879

TSH3
Teashirt homolog 3

1

17

High-throughput

0.479

High

727881

BCOR
BCL-6 corepressor

1

18

High-throughput

0.479

High

727883

UBN2
Ubinuclein-2

1

20

High-throughput

0.479

High

727885

I2BP2
Interferon regulatory factor 2-binding protein 2

1

9

High-throughput

0.479

High

727887

LDB1
LIM domain-binding protein 1

1

5

High-throughput

0.479

High

727888

ZFHX4
Zinc finger homeobox protein 4

1

15

High-throughput

0.479

High

727890

P66A
Transcriptional repressor p66-alpha

1

15

High-throughput

0.479

High

727891

I2BP1
Interferon regulatory factor 2-binding protein 1

1

9

High-throughput

0.479

High

727892

FOXP4
Forkhead box protein P4

1

20

High-throughput

0.479

High

727896

ZMIZ2
Zinc finger MIZ domain-containing protein 2

1

20

High-throughput

0.479

High

727897

KDM2B
Lysine-specific demethylase 2B

1

6

High-throughput

0.479

High

727898

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

727899

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

4

High-throughput

0.479

High

727900

P66B
Transcriptional repressor p66-beta

1

15

High-throughput

0.479

High

727902

MAML1
Mastermind-like protein 1

1

20

High-throughput

0.479

High

727904

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

9

High-throughput

0.479

High

727906

ZN503
Zinc finger protein 503

1

3

High-throughput

0.479

High

727908

ZN521
Zinc finger protein 521

1

4

High-throughput

0.479

High

727909

NACC1
Nucleus accumbens-associated protein 1

1

20

High-throughput

0.479

High

727912

PYGO2
Pygopus homolog 2

1

2

High-throughput

0.479

High

727914

PCGF1
Polycomb group RING finger protein 1

1

19

High-throughput

0.479

High

727915

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.479

High

727917

SSBP3
Single-stranded DNA-binding protein 3

1

16

High-throughput

0.479

High

727920

SP130
Histone deacetylase complex subunit SAP130

1

20

High-throughput

0.479

High

727921

ING2
Inhibitor of growth protein 2

1

20

High-throughput

0.479

High

727922

I2BPL
Probable E3 ubiquitin-protein ligase IRF2BPL

1

18

High-throughput

0.479

High

727923

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.479

High

727925

ZHX3
Zinc fingers and homeoboxes protein 3

1

20

High-throughput

0.479

High

727926

ZN703
Zinc finger protein 703

1

17

High-throughput

0.479

High

727928

PRD16
Histone-lysine N-methyltransferase PRDM16

1

12

High-throughput

0.479

High

727934

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

20

High-throughput

0.479

High

727935

RCOR3
REST corepressor 3

1

20

High-throughput

0.479

High

727936

MBD2
Methyl-CpG-binding domain protein 2

1

10

High-throughput

0.479

High

727937

TCF20
Transcription factor 20

1

20

High-throughput

0.479

High

727938

TRPS1
Zinc finger transcription factor Trps1

1

20

High-throughput

0.479

High

727939

ING1
Inhibitor of growth protein 1

1

20

High-throughput

0.479

High

727940

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

727942

SATB2
DNA-binding protein SATB2

1

13

High-throughput

0.479

High

727943

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

727944

ZBTB1
Zinc finger and BTB domain-containing protein 1

1

7

High-throughput

0.479

High

727945

ZN281
Zinc finger protein 281

1

16

High-throughput

0.479

High

727950

RAI2
Retinoic acid-induced protein 2

1

1

High-throughput

0.479

High

727951

NCOR2
Nuclear receptor corepressor 2

1

20

High-throughput

0.479

High

727952

NCOA3
Nuclear receptor coactivator 3

1

20

High-throughput

0.479

High

727953

ZHX2
Zinc fingers and homeoboxes protein 2

1

20

High-throughput

0.479

High

316308

TYDP2
Tyrosyl-DNA phosphodiesterase 2

1

0

High-throughput

0.458

High

224607

TIM8A
Mitochondrial import inner membrane translocase subunit Tim8 A

1

5

High-throughput

0.457

High

279460

FLOT1
Flotillin-1

1

7

High-throughput

0.457

High

727834

ATPG
ATP synthase subunit gamma, mitochondrial

1

1

High-throughput

0.457

High

727854

LG3BP
Galectin-3-binding protein

1

10

High-throughput

0.457

High

727865

FLOT2
Flotillin-2

1

7

High-throughput

0.457

High

727907

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

1

High-throughput

0.457

High

727931

ATD3A
ATPase family AAA domain-containing protein 3A

1

7

High-throughput

0.457

High

727946

RT23
Small ribosomal subunit protein mS23

1

2

High-throughput

0.457

High

727947

PRC2C
Protein PRRC2C

1

20

High-throughput

0.457

High

147053

NEMP1
Nuclear envelope integral membrane protein 1

1

1

High-throughput

0.437

High

727869

GSE1
Genetic suppressor element 1

1

4

High-throughput

0.437

High

727875

QSER1
Glutamine and serine-rich protein 1

1

20

High-throughput

0.437

High

727882

CO039
Uncharacterized protein C15orf39

1

9

High-throughput

0.437

High

727889

PRSR1
Proline and serine-rich protein 1

1

20

High-throughput

0.437

High

727893

DHX40
Probable ATP-dependent RNA helicase DHX40

1

6

High-throughput

0.437

High

727924

CPVL
Probable serine carboxypeptidase CPVL

1

2

High-throughput

0.437

High

727927

FBRS
Probable fibrosin-1

1

4

High-throughput

0.437

High

727929

FBSL
Fibrosin-1-like protein

1

4

High-throughput

0.437

High

727948

TIM8B
Mitochondrial import inner membrane translocase subunit Tim8 B

1

5

High-throughput

0.437

High

727901

PMGT1
Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

1

0

High-throughput

0.282

High

454012

COX6C
Cytochrome c oxidase subunit 6C

1

0

High-throughput

0.261

Low

727880

RADX
RPA-related protein RADX

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024