Protein: FRU
Sex determination protein fruitless

Gene: FRU
Organism: Drosophila melanogaster
Interactions: 20
UniProt ID: Q8IN81

Gene Ontology (top 5):
GO:0002118 - aggressive behavior
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

838650

LOLA2
Longitudinals lacking protein, isoforms H/M/V

1

19

Small-scale

0.618

High

426695

HP1
Heterochromatin protein 1

1

14

Small-scale

0.536

High

1303591

HDAC1
Histone deacetylase HDAC1

1

20

Small-scale

0.536

High

1303593

Q9VDK5
Bonus, isoform A

1

20

Small-scale

0.536

High

72170

A8WHL4
Bonus, isoform B

1

20

Small-scale

0.479

High

628535

USP
Protein ultraspiracle

1

17

Small-scale

0.479

High

756463

ECR
Ecdysone receptor

1

20

Small-scale

0.479

High

1302153

TAD2B
Transcriptional adapter 2b

1

6

Small-scale

0.479

High

1303592

Q9V4B8
RE68558p

1

10

High-throughput

0.464

High

1303596

Q9VJM1
GEO13348p1

1

4

High-throughput

0.464

High

1303590

Q8T052
TATA box-binding protein-like 1

1

0

Small-scale

0.458

High

1303594

FLNA
Filamin-A

1

14

High-throughput

0.442

High

96072

E8NH67
Asperous, isoform B

1

5

High-throughput

0.439

High

1303598

Q9VU12
Uncharacterized protein, isoform B

1

3

High-throughput

0.439

High

1303589

Q8IQI1
Uncharacterized protein, isoform A

1

3

High-throughput

0.417

High

1303599

Q9W5X1
Asperous, isoform A

1

5

High-throughput

0.417

High

1174952

NETB
Netrin-B

1

2

High-throughput

0.407

High

1173742

SEM2A
Semaphorin-2A

1

0

High-throughput

0.265

Low

1303595

Q9VJ22
GH09876p

1

0

High-throughput

0.265

Low

1303597

Q9VR24
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025