Protein: NUP98
Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)]

Gene: NUP98
Organism: Homo sapiens
Interactions: 186
UniProt ID: P52948

Gene Ontology (top 5):
GO:0000973 - post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005635 - nuclear envelope

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

857963

RAE1L
mRNA export factor RAE1

15

20

Small-scale

0.988

High

858014

NUP43
Nucleoporin Nup43

7

11

High-throughput

0.963

High

857955

NU107
Nuclear pore complex protein Nup107

7

11

Small-scale

0.958

High

857954

SEC13
Protein SEC13 homolog

5

20

High-throughput

0.927

High

857952

NUP98
Nuclear pore complex protein Nup98-Nup96

2

19

Small-scale

0.768

High

858064

NXF1
Nuclear RNA export factor 1

7

14

Small-scale

0.746

High

858019

NU133
Nuclear pore complex protein Nup133

5

10

Small-scale

0.718

High

857978

IMB1
Importin subunit beta-1

5

20

Small-scale

0.713

High

858038

NUP88
Nuclear pore complex protein Nup88

4

3

Small-scale

0.705

High

359790

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

5

15

High-throughput

0.702

High

858015

NUP37
Nucleoporin Nup37

1

7

High-throughput

0.691

High

858034

SEH1
Nucleoporin SEH1

1

20

High-throughput

0.691

High

858044

NUP85
Nuclear pore complex protein Nup85

4

11

Small-scale

0.686

High

273741

NU155
Nuclear pore complex protein Nup155

3

20

Small-scale

0.651

High

858023

CBP
CREB-binding protein

2

7

Small-scale

0.629

High

857986

CDC37
Hsp90 co-chaperone Cdc37

2

1

High-throughput

0.628

High

858063

SPAST
Spastin

2

7

High-throughput

0.628

High

267967

EED
Polycomb protein EED

1

11

High-throughput

0.618

High

857957

WDR5
WD repeat-containing protein 5

1

6

High-throughput

0.618

High

857968

CDC20
Cell division cycle protein 20 homolog

1

7

Small-scale

0.618

High

858072

FZR1
Fizzy-related protein homolog

1

8

Small-scale

0.618

High

162534

XPO1
Exportin-1

2

20

Small-scale

0.611

High

727227

NU214
Nuclear pore complex protein Nup214

2

20

Small-scale

0.611

High

857979

NUMA1
Nuclear mitotic apparatus protein 1

2

5

Small-scale

0.611

High

853826

NCBP2
Nuclear cap-binding protein subunit 2

2

3

High-throughput

0.601

High

518842

TPR
Nucleoprotein TPR

2

20

Small-scale

0.595

High

858020

NU205
Nuclear pore complex protein Nup205

2

14

Small-scale

0.595

High

226940

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

857956

SC61B
Protein transport protein Sec61 subunit beta

2

2

High-throughput

0.584

High

857967

NU160
Nuclear pore complex protein Nup160

2

4

High-throughput

0.584

High

858016

NUP35
Nucleoporin NUP35

2

4

High-throughput

0.584

High

858074

FAF1
FAS-associated factor 1

2

1

High-throughput

0.584

High

70661

MYO9A
Unconventional myosin-IXa

2

4

High-throughput

0.571

High

857977

RRP1B
Ribosomal RNA processing protein 1 homolog B

2

2

High-throughput

0.571

High

858008

ARHGJ
Rho guanine nucleotide exchange factor 19

2

5

High-throughput

0.571

High

857962

CSK21
Casein kinase II subunit alpha

1

4

High-throughput

0.569

High

857974

HDAC1
Histone deacetylase 1

1

3

Small-scale

0.561

High

858007

CMTD1
Catechol O-methyltransferase domain-containing protein 1

2

1

High-throughput

0.558

High

626080

APC
Adenomatous polyposis coli protein

1

5

High-throughput

0.541

High

483390

RGPD1
RANBP2-like and GRIP domain-containing protein 1

1

20

High-throughput

0.536

High

675141

CLIP1
CAP-Gly domain-containing linker protein 1

1

3

High-throughput

0.536

High

796711

RANG
Ran-specific GTPase-activating protein

1

20

High-throughput

0.536

High

800732

MK08
Mitogen-activated protein kinase 8

1

6

High-throughput

0.536

High

834568

NU153
Nuclear pore complex protein Nup153

1

19

High-throughput

0.536

High

851398

NEK4
Serine/threonine-protein kinase Nek4

1

6

High-throughput

0.536

High

857953

LIMK1
LIM domain kinase 1

1

6

High-throughput

0.536

High

857959

RAN
GTP-binding nuclear protein Ran

1

5

High-throughput

0.536

High

857961

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.536

High

857976

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

6

High-throughput

0.536

High

857984

MARE1
Microtubule-associated protein RP/EB family member 1

1

3

High-throughput

0.536

High

858043

NUP58
Nucleoporin p58/p45

1

19

High-throughput

0.536

High

858045

HDAC8
Histone deacetylase 8

1

4

High-throughput

0.536

High

858050

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.536

High

858059

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.536

High

858077

RPKL1
Ribosomal protein S6 kinase-like 1

1

5

High-throughput

0.536

High

857988

H31T
Histone H3.1t

1

11

High-throughput

0.515

High

858025

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

12

High-throughput

0.515

High

858026

H2B1H
Histone H2B type 1-H

1

11

High-throughput

0.515

High

858041

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

7

Small-scale

0.515

High

858048

QRIC2
Glutamine-rich protein 2

1

14

High-throughput

0.515

High

858053

MOB1A
MOB kinase activator 1A

1

1

High-throughput

0.515

High

214890

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.513

High

454690

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

858000

TF2H5
General transcription factor IIH subunit 5

1

0

High-throughput

0.513

High

858071

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.513

High

857960

DYLT1
Dynein light chain Tctex-type 1

1

2

Small-scale

0.512

High

155553

TNPO2
Transportin-2

1

20

Small-scale

0.501

High

857991

NU188
Nucleoporin NUP188

1

2

Small-scale

0.501

High

858024

TNPO1
Transportin-1

1

20

Small-scale

0.501

High

639566

TNR5
Tumor necrosis factor receptor superfamily member 5

1

3

High-throughput

0.489

High

857969

FOXL1
Forkhead box protein L1

1

8

High-throughput

0.489

High

857998

FOXI2
Forkhead box protein I2

1

8

High-throughput

0.489

High

858033

HDA11
Histone deacetylase 11

1

7

High-throughput

0.489

High

858047

FOXQ1
Forkhead box protein Q1

1

9

High-throughput

0.489

High

858062

PIM2
Serine/threonine-protein kinase pim-2

1

4

High-throughput

0.489

High

122582

MEN1
Menin

1

2

High-throughput

0.479

High

148567

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.479

High

209798

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.479

High

214158

SPOP
Speckle-type POZ protein

1

4

High-throughput

0.479

High

232820

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

5

High-throughput

0.479

High

233301

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

244159

BRD4
Bromodomain-containing protein 4

1

11

High-throughput

0.479

High

255614

OBSL1
Obscurin-like protein 1

1

4

High-throughput

0.479

High

308526

KI20A
Kinesin-like protein KIF20A

1

6

High-throughput

0.479

High

552304

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

569444

CEBPB
CCAAT/enhancer-binding protein beta

1

7

High-throughput

0.479

High

573625

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

4

High-throughput

0.479

High

595161

LMNB1
Lamin-B1

1

15

High-throughput

0.479

High

622569

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

2

High-throughput

0.479

High

650747

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

672792

CDC27
Cell division cycle protein 27 homolog

1

4

Small-scale

0.479

High

684548

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.479

High

716899

CTNB1
Catenin beta-1

1

20

High-throughput

0.479

High

720039

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.479

High

781608

ETV6
Transcription factor ETV6

1

8

High-throughput

0.479

High

790648

WASP
Actin nucleation-promoting factor WAS

1

4

Small-scale

0.479

High

799066

NKX21
Homeobox protein Nkx-2.1

1

14

High-throughput

0.479

High

823739

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

838733

EMD
Emerin

1

2

High-throughput

0.479

High

841582

CDK9
Cyclin-dependent kinase 9

1

4

High-throughput

0.479

High

857958

H4
Histone H4

1

4

High-throughput

0.479

High

857965

CKAP4
Cytoskeleton-associated protein 4

1

7

High-throughput

0.479

High

857966

EP300
Histone acetyltransferase p300

1

6

Small-scale

0.479

High

857970

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

1

Small-scale

0.479

High

857971

G3BP1
Ras GTPase-activating protein-binding protein 1

1

8

High-throughput

0.479

High

857972

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

857973

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

6

Small-scale

0.479

High

857980

CUL7
Cullin-7

1

5

High-throughput

0.479

High

857982

KIF14
Kinesin-like protein KIF14

1

3

High-throughput

0.479

High

857985

EZH2
Histone-lysine N-methyltransferase EZH2

1

9

High-throughput

0.479

High

857987

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

857989

GLE1
mRNA export factor GLE1

1

11

High-throughput

0.479

High

857992

RNF43
E3 ubiquitin-protein ligase RNF43

1

5

High-throughput

0.479

High

857993

VIR
Protein virilizer homolog

1

1

High-throughput

0.479

High

857997

SYNE3
Nesprin-3

1

2

High-throughput

0.479

High

858003

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

10

High-throughput

0.479

High

858004

SLN11
Schlafen family member 11

1

2

High-throughput

0.479

High

858005

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

3

High-throughput

0.479

High

858006

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

858009

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

858011

SIR6
NAD-dependent protein deacylase sirtuin-6

1

7

High-throughput

0.479

High

858017

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

858022

ESR2
Estrogen receptor beta

1

15

High-throughput

0.479

High

858027

FBX32
F-box only protein 32

1

1

High-throughput

0.479

High

858039

TBX5
T-box transcription factor TBX5

1

4

High-throughput

0.479

High

858040

B9D2
B9 domain-containing protein 2

1

1

High-throughput

0.479

High

858054

ECT2
Protein ECT2

1

6

High-throughput

0.479

High

858055

ANLN
Anillin

1

2

High-throughput

0.479

High

858056

PAR11
Protein mono-ADP-ribosyltransferase PARP11

1

6

High-throughput

0.479

High

858057

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

858058

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

858065

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

858066

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.479

High

858070

NUP50
Nuclear pore complex protein Nup50

1

20

High-throughput

0.479

High

858073

APC10
Anaphase-promoting complex subunit 10

1

5

Small-scale

0.479

High

858021

TTC9A
Tetratricopeptide repeat protein 9A

1

3

High-throughput

0.470

High

119270

LEG9
Galectin-9

1

0

High-throughput

0.458

High

330187

PTTG1
Securin

1

0

Small-scale

0.458

High

418071

NPM
Nucleophosmin

1

0

Small-scale

0.458

High

785783

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

858012

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

858029

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

858032

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

858035

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

858036

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

858052

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

858060

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.458

High

858068

APC4
Anaphase-promoting complex subunit 4

1

0

Small-scale

0.458

High

517149

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.457

High

135232

E2F3
Transcription factor E2F3

1

2

Small-scale

0.445

High

346302

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.445

High

857990

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

858075

DICER
Endoribonuclease Dicer

1

7

Small-scale

0.445

High

858069

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.438

High

129723

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

4

High-throughput

0.437

High

313167

RPGF3
Rap guanine nucleotide exchange factor 3

1

3

Small-scale

0.437

High

351316

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

9

High-throughput

0.437

High

857981

HAPR1
HUWE1-associated protein modifying stress responses 1

1

2

Small-scale

0.437

High

857983

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

2

High-throughput

0.437

High

857995

LMBRL
Protein LMBR1L

1

3

High-throughput

0.437

High

857996

DPPA3
Developmental pluripotency-associated protein 3

1

1

High-throughput

0.437

High

857999

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

858001

UBP53
Inactive ubiquitin carboxyl-terminal hydrolase 53

1

6

Small-scale

0.437

High

858002

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

6

High-throughput

0.437

High

858018

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

3

High-throughput

0.437

High

858028

RN166
E3 ubiquitin-protein ligase RNF166

1

6

High-throughput

0.437

High

858030

ARL8A
ADP-ribosylation factor-like protein 8A

1

1

High-throughput

0.437

High

858046

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

858049

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

858051

PKHA4
Pleckstrin homology domain-containing family A member 4

1

8

High-throughput

0.437

High

858067

DS13B
Dual specificity protein phosphatase 13B

1

1

High-throughput

0.437

High

858076

CLC11
C-type lectin domain family 11 member A

1

2

High-throughput

0.437

High

301080

FBX21
F-box only protein 21

1

0

Small-scale

0.426

High

702206

CD70
CD70 antigen

2

0

High-throughput

0.328

High

858013

UXS1
UDP-glucuronic acid decarboxylase 1

2

0

High-throughput

0.328

High

858031

F136A
Protein FAM136A

2

0

High-throughput

0.328

High

858010

PNKD
Probable hydrolase PNKD

2

0

High-throughput

0.318

High

238853

TPST2
Protein-tyrosine sulfotransferase 2

1

0

High-throughput

0.279

Low

857994

VASN
Vasorin

1

0

High-throughput

0.279

Low

858061

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.279

Low

795083

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.249

Low

857964

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.249

Low

857975

STIM1
Stromal interaction molecule 1

1

0

High-throughput

0.249

Low

858037

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

858042

DERL1
Derlin-1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024