Protein: MYL6B
Myosin light chain 6B (Myosin light chain 1 slow-twitch muscle A isoform) (MLC1sa) (Smooth muscle and nonmuscle myosin light chain alkali 6B)

Gene: MYL6B
Organism: Homo sapiens
Interactions: 107
UniProt ID: P14649

Gene Ontology (top 5):
GO:0003774 - cytoskeletal motor activity
GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0005859 - muscle myosin complex
GO:0006936 - muscle contraction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

538647

IQGA1
Ras GTPase-activating-like protein IQGAP1

4

20

Small-scale

0.694

High

538653

MYL6
Myosin light polypeptide 6

3

15

High-throughput

0.675

High

538642

MYH9
Myosin-9

3

17

High-throughput

0.667

High

538705

ANLN
Anillin

3

2

High-throughput

0.656

High

538657

RAC1
Ras-related C3 botulinum toxin substrate 1

3

12

High-throughput

0.650

High

538690

MY18A
Unconventional myosin-XVIIIa

2

20

High-throughput

0.601

High

159536

ML12B
Myosin regulatory light chain 12B

1

18

High-throughput

0.536

High

368917

ESR1
Estrogen receptor

1

4

High-throughput

0.536

High

538637

ML12A
Myosin regulatory light chain 12A

1

19

High-throughput

0.536

High

538639

MYL9
Myosin regulatory light polypeptide 9

1

19

High-throughput

0.536

High

538643

MYH10
Myosin-10

1

17

High-throughput

0.536

High

538648

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.536

High

538654

CDC42
Cell division control protein 42 homolog

1

12

High-throughput

0.536

High

538665

MYO9B
Unconventional myosin-IXb

1

18

High-throughput

0.536

High

538692

MYO19
Unconventional myosin-XIX

1

20

High-throughput

0.536

High

538706

PDLI7
PDZ and LIM domain protein 7

1

3

High-throughput

0.536

High

538709

MYO6
Unconventional myosin-VI

1

20

High-throughput

0.536

High

538708

DUX4
Double homeobox protein 4

1

4

High-throughput

0.516

High

538710

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.513

High

538636

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

7

High-throughput

0.489

High

70646

MYO9A
Unconventional myosin-IXa

1

20

High-throughput

0.479

High

120294

RHOD
Rho-related GTP-binding protein RhoD

1

16

High-throughput

0.479

High

148350

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.479

High

209635

PRC1
Protein regulator of cytokinesis 1

1

6

High-throughput

0.479

High

301592

TRI37
E3 ubiquitin-protein ligase TRIM37

1

5

High-throughput

0.479

High

345301

FOS
Protein c-Fos

1

5

High-throughput

0.479

High

373627

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

397756

ISG15
Ubiquitin-like protein ISG15

1

10

High-throughput

0.479

High

501629

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

538638

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

538646

YAP1
Transcriptional coactivator YAP1

1

5

High-throughput

0.479

High

538649

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.479

High

538652

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.479

High

538655

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

1

1

High-throughput

0.479

High

538656

RHOB
Rho-related GTP-binding protein RhoB

1

15

High-throughput

0.479

High

538660

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

2

High-throughput

0.479

High

538662

FOXO1
Forkhead box protein O1

1

1

High-throughput

0.479

High

538663

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.479

High

538664

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

538666

CUL1
Cullin-1

1

6

High-throughput

0.479

High

538667

CUL3
Cullin-3

1

6

High-throughput

0.479

High

538668

ARHG7
Rho guanine nucleotide exchange factor 7

1

2

High-throughput

0.479

High

538670

TNIP1
TNFAIP3-interacting protein 1

1

19

High-throughput

0.479

High

538671

KIF14
Kinesin-like protein KIF14

1

7

High-throughput

0.479

High

538675

LARP7
La-related protein 7

1

2

High-throughput

0.479

High

538676

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

3

High-throughput

0.479

High

538677

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

6

High-throughput

0.479

High

538680

MYH14
Myosin-14

1

17

High-throughput

0.479

High

538681

ARHG8
Neuroepithelial cell-transforming gene 1 protein

1

8

High-throughput

0.479

High

538682

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

3

High-throughput

0.479

High

538683

SLN11
Schlafen family member 11

1

1

Small-scale

0.479

High

538684

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

20

High-throughput

0.479

High

538691

FBXW7
F-box/WD repeat-containing protein 7

1

2

High-throughput

0.479

High

538697

MEP50
Methylosome protein WDR77

1

5

High-throughput

0.479

High

538699

CCDC8
Coiled-coil domain-containing protein 8

1

3

High-throughput

0.479

High

538700

CHM4B
Charged multivesicular body protein 4b

1

2

High-throughput

0.479

High

538702

ECT2
Protein ECT2

1

8

High-throughput

0.479

High

538703

RHOF
Rho-related GTP-binding protein RhoF

1

16

High-throughput

0.479

High

538707

HDAC6
Histone deacetylase 6

1

5

High-throughput

0.479

High

538712

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

12

High-throughput

0.479

High

386021

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

538635

H2AX
Histone H2AX

1

0

High-throughput

0.458

High

538641

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

538645

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

0

High-throughput

0.458

High

538650

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

538659

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

538685

CEP57
Centrosomal protein of 57 kDa

1

0

High-throughput

0.458

High

538689

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.458

High

538704

NGB
Neuroglobin

1

0

High-throughput

0.458

High

538711

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

0

High-throughput

0.458

High

483897

CALM1
Calmodulin-1

1

17

High-throughput

0.445

High

483970

CALM2
Calmodulin-2

1

17

High-throughput

0.445

High

484054

CALM3
Calmodulin-3

1

17

High-throughput

0.445

High

496216

TAU
Microtubule-associated protein tau

1

8

High-throughput

0.445

High

528470

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.445

High

538633

MYL6B
Myosin light chain 6B

1

17

High-throughput

0.445

High

538640

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.445

High

538658

RHOG
Rho-related GTP-binding protein RhoG

1

12

Small-scale

0.445

High

538694

CEP63
Centrosomal protein of 63 kDa

1

19

High-throughput

0.445

High

538695

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.445

High

294328

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.437

High

302865

HEXI1
Protein HEXIM1

1

1

High-throughput

0.437

High

308374

KI20A
Kinesin-like protein KIF20A

1

12

High-throughput

0.437

High

345827

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.437

High

352469

TNFA
Tumor necrosis factor

1

2

High-throughput

0.437

High

378976

MYCN
N-myc proto-oncogene protein

1

6

High-throughput

0.437

High

434917

SP1
Transcription factor Sp1

1

2

Small-scale

0.437

High

538651

R144A
E3 ubiquitin-protein ligase RNF144A

1

2

Small-scale

0.437

High

538669

RBM39
RNA-binding protein 39

1

1

High-throughput

0.437

High

538672

BRD3
Bromodomain-containing protein 3

1

1

High-throughput

0.437

High

538674

RHOH
Rho-related GTP-binding protein RhoH

1

16

High-throughput

0.437

High

538678

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

538679

MEPCE
7SK snRNA methylphosphate capping enzyme

1

1

High-throughput

0.437

High

538686

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.437

High

538687

FHI1B
FHF complex subunit HOOK-interacting protein 1B

1

1

High-throughput

0.437

High

538693

RHOV
Rho-related GTP-binding protein RhoV

1

14

High-throughput

0.437

High

538696

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.437

High

538698

RHBT2
Rho-related BTB domain-containing protein 2

1

14

High-throughput

0.437

High

538701

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.437

High

239752

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

10

High-throughput

0.407

High

401346

JUN
Transcription factor Jun

1

3

High-throughput

0.407

High

538661

TAGL
Transgelin

1

20

High-throughput

0.407

High

538673

SP17
Sperm surface protein Sp17

6

0

High-throughput

0.385

High

538634

TFE2
Transcription factor E2-alpha

1

0

High-throughput

0.249

Low

538644

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

538688

DTX3
Probable E3 ubiquitin-protein ligase DTX3

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024