Protein: IKBB
NF-kappa-B inhibitor beta (NF-kappa-BIB) (I-kappa-B-beta) (IkB-B) (IkB-beta) (IkappaBbeta) (Thyroid receptor-interacting protein 9) (TR-interacting protein 9) (TRIP-9)

Gene: IKBB, NFKBIB
Organism: Homo sapiens
Interactions: 112
UniProt ID: Q15653

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006351 - DNA-templated transcription
GO:0006954 - inflammatory response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

978766

TF65
Transcription factor p65

16

20

Small-scale

0.988

High

981586

REL
Proto-oncogene c-Rel

9

20

Small-scale

0.969

High

587589

NFKB1
Nuclear factor NF-kappa-B p105 subunit

7

20

High-throughput

0.966

High

1076391

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

7

18

Small-scale

0.958

High

158478

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

6

20

Small-scale

0.947

High

639750

IKBA
NF-kappa-B inhibitor alpha

5

16

Small-scale

0.931

High

167551

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

5

20

Small-scale

0.920

High

961391

NFKB2
Nuclear factor NF-kappa-B p100 subunit

4

18

High-throughput

0.895

High

1076400

NEMO
NF-kappa-B essential modulator

4

20

Small-scale

0.886

High

934190

CSK21
Casein kinase II subunit alpha

1

9

Small-scale

0.724

High

617561

CRCM
Colorectal mutant cancer protein

4

4

High-throughput

0.697

High

589870

TBP
TATA-box-binding protein

4

1

High-throughput

0.694

High

272869

KS6A4
Ribosomal protein S6 kinase alpha-4

1

7

High-throughput

0.691

High

964488

RELB
Transcription factor RelB

1

20

High-throughput

0.691

High

1076377

ARAP3
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3

1

11

High-throughput

0.691

High

1076378

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

18

High-throughput

0.691

High

1076382

BIRC7
Baculoviral IAP repeat-containing protein 7

3

8

High-throughput

0.667

High

1076397

FBW1A
F-box/WD repeat-containing protein 1A

3

20

Small-scale

0.650

High

1076362

BAK
Bcl-2 homologous antagonist/killer

1

4

Small-scale

0.647

High

338472

EGFR
Epidermal growth factor receptor

1

14

High-throughput

0.646

High

1050112

GIT2
ARF GTPase-activating protein GIT2

1

18

High-throughput

0.625

High

1044594

FHL3
Four and a half LIM domains protein 3

1

8

High-throughput

0.621

High

1076384

TONSL
Tonsoku-like protein

1

19

High-throughput

0.618

High

428225

TBB5
Tubulin beta chain

1

16

High-throughput

0.618

High

874969

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.618

High

1076360

IKBB
NF-kappa-B inhibitor beta

1

17

High-throughput

0.618

High

1076368

TBA1A
Tubulin alpha-1A chain

1

15

High-throughput

0.618

High

1076392

KBRS1
NF-kappa-B inhibitor-interacting Ras-like protein 1

1

17

Small-scale

0.618

High

1076394

NGAP
Ras GTPase-activating protein nGAP

2

11

High-throughput

0.611

High

1076386

BTBD6
BTB/POZ domain-containing protein 6

2

1

High-throughput

0.606

High

1076373

VPS52
Vacuolar protein sorting-associated protein 52 homolog

2

0

High-throughput

0.601

High

901576

LYSC
Lysozyme C

1

0

High-throughput

0.586

High

1076383

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

Small-scale

0.578

High

312068

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

5

Small-scale

0.552

High

673404

MPIP1
M-phase inducer phosphatase 1

1

1

High-throughput

0.541

High

152878

APAF
Apoptotic protease-activating factor 1

1

5

High-throughput

0.536

High

279016

RAD17
Cell cycle checkpoint protein RAD17

1

2

High-throughput

0.536

High

1076363

RGL3
Ral guanine nucleotide dissociation stimulator-like 3

1

2

High-throughput

0.536

High

1076367

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1

1

1

High-throughput

0.536

High

1076387

TGS1
Trimethylguanosine synthase

1

1

High-throughput

0.536

High

587176

RXRA
Retinoic acid receptor RXR-alpha

1

15

Small-scale

0.527

High

1076370

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

3

High-throughput

0.515

High

176603

FANCA
Fanconi anemia group A protein

1

0

High-throughput

0.513

High

1063324

CND1
Condensin complex subunit 1

1

0

High-throughput

0.513

High

1076380

SYMPK
Symplekin

1

0

High-throughput

0.513

High

1076385

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.513

High

394763

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

740534

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.501

High

1076379

ESR2
Estrogen receptor beta

1

20

Small-scale

0.501

High

1076399

NCOR2
Nuclear receptor corepressor 2

1

19

Small-scale

0.501

High

1076374

BANP
Protein BANP

1

1

High-throughput

0.489

High

70677

MYO9A
Unconventional myosin-IXa

1

10

High-throughput

0.479

High

162776

XPO1
Exportin-1

1

12

High-throughput

0.479

High

169853

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.479

High

179651

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

7

High-throughput

0.479

High

238065

PDE8A
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

1

3

Small-scale

0.479

High

323778

BAG2
BAG family molecular chaperone regulator 2

1

5

High-throughput

0.479

High

324412

BAG3
BAG family molecular chaperone regulator 3

1

4

High-throughput

0.479

High

377350

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

396742

S10A8
Protein S100-A8

1

2

High-throughput

0.479

High

430962

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.479

High

431882

HS90A
Heat shock protein HSP 90-alpha

1

13

High-throughput

0.479

High

438197

HS90B
Heat shock protein HSP 90-beta

1

13

High-throughput

0.479

High

475034

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

8

High-throughput

0.479

High

502137

BIP
Endoplasmic reticulum chaperone BiP

1

20

High-throughput

0.479

High

504130

HSP7C
Heat shock cognate 71 kDa protein

1

20

High-throughput

0.479

High

551718

DESP
Desmoplakin

1

20

High-throughput

0.479

High

575061

RL7
Large ribosomal subunit protein uL30

1

2

High-throughput

0.479

High

582310

NUCL
Nucleolin

1

5

High-throughput

0.479

High

613469

SFPQ
Splicing factor, proline- and glutamine-rich

1

8

High-throughput

0.479

High

713979

HS71L
Heat shock 70 kDa protein 1-like

1

20

High-throughput

0.479

High

751641

GRP75
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

783042

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.479

High

789805

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

809315

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

11

High-throughput

0.479

High

852938

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

7

High-throughput

0.479

High

853303

IMA1
Importin subunit alpha-1

1

2

High-throughput

0.479

High

921859

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.479

High

923033

RL11
Large ribosomal subunit protein uL5

1

3

High-throughput

0.479

High

928924

SKP1
S-phase kinase-associated protein 1

1

4

High-throughput

0.479

High

929874

ACTG
Actin, cytoplasmic 2

1

12

High-throughput

0.479

High

960811

CLH1
Clathrin heavy chain 1

1

4

High-throughput

0.479

High

962107

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

9

High-throughput

0.479

High

1040023

IQGA2
Ras GTPase-activating-like protein IQGAP2

1

13

High-throughput

0.479

High

1041001

CUL1
Cullin-1

1

19

High-throughput

0.479

High

1076365

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.479

High

1076369

BRAP
BRCA1-associated protein

1

9

Small-scale

0.479

High

1076372

CCAR2
Cell cycle and apoptosis regulator protein 2

1

1

High-throughput

0.479

High

1076376

KI18A
Kinesin-like protein KIF18A

1

5

High-throughput

0.479

High

1076381

EXOC4
Exocyst complex component 4

1

1

High-throughput

0.479

High

1076390

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.479

High

1076395

FBW1B
F-box/WD repeat-containing protein 11

1

20

High-throughput

0.479

High

1076396

Q9UQC1
Heat shock protein 72

1

20

High-throughput

0.479

High

574353

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.458

High

854307

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.458

High

921121

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

High-throughput

0.458

High

1076361

PDCD2
Programmed cell death protein 2

1

0

High-throughput

0.458

High

317117

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

1

High-throughput

0.437

High

484453

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

1

High-throughput

0.437

High

803120

IF2M
Translation initiation factor IF-2, mitochondrial

1

1

High-throughput

0.437

High

1076364

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

4

High-throughput

0.437

High

1076375

RLA0L
Putative ribosomal protein uL10-like

1

1

High-throughput

0.437

High

1076388

Q9BSR4
DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.437

High

1076393

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

1

High-throughput

0.437

High

1076398

SRPRB
Signal recognition particle receptor subunit beta

1

6

High-throughput

0.437

High

1076389

RPA49
DNA-directed RNA polymerase I subunit RPA49

4

0

High-throughput

0.362

High

568456

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

237690

TSN1
Tetraspanin-1

1

0

High-throughput

0.282

High

1076366

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

1

0

High-throughput

0.279

Low

372863

SLPI
Antileukoproteinase

1

0

High-throughput

0.249

Low

1076371

CC28A
Coiled-coil domain-containing protein 28A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024