Protein: PHS
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)

Gene: PHS, Pcbd1
Organism: Mus musculus
Interactions: 20
UniProt ID: P61458

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0004505 - phenylalanine 4-monooxygenase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

961662

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

5

High-throughput

0.698

High

961671

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

5

Small-scale

0.618

High

648021

HNF1A
Hepatocyte nuclear factor 1-alpha

2

6

Small-scale

0.614

High

73938

BRPF1
Peregrin

1

2

High-throughput

0.541

High

204314

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

1

High-throughput

0.541

High

267024

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.541

High

699383

HNF1B
Hepatocyte nuclear factor 1-beta

1

6

High-throughput

0.541

High

961667

NRIF1
Neurotrophin receptor-interacting factor 1

1

1

High-throughput

0.541

High

663584

TISB
mRNA decay activator protein ZFP36L1

1

0

High-throughput

0.518

High

961664

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.518

High

961665

ERCC8
DNA excision repair protein ERCC-8

1

0

High-throughput

0.518

High

961669

PAWR
PRKC apoptosis WT1 regulator protein

1

0

High-throughput

0.518

High

961672

SRBP1
Sterol regulatory element-binding protein 1

1

0

High-throughput

0.518

High

961674

TLE6
Transducin-like enhancer protein 6

1

0

High-throughput

0.518

High

961666

ASB15
Ankyrin repeat and SOCS box protein 15

1

1

High-throughput

0.494

High

961668

CERS2
Ceramide synthase 2

1

1

High-throughput

0.494

High

961670

ZDH13
Palmitoyltransferase ZDHHC13

1

1

High-throughput

0.494

High

961673

ASB3
Ankyrin repeat and SOCS box protein 3

1

1

High-throughput

0.494

High

961663

ARGL1
Arginine and glutamate-rich protein 1

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025