Protein: TLE6
Transducin-like enhancer protein 6 (Groucho-related protein 6)

Gene: TLE6
Organism: Mus musculus
Interactions: 25
UniProt ID: Q9WVB3

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005938 - cell cortex
GO:0007015 - actin filament organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1423830

OOEP
Oocyte-expressed protein homolog

1

3

Small-scale

0.554

High

74304

EP300
Histone acetyltransferase p300

1

16

High-throughput

0.541

High

204354

ALX4
Homeobox protein aristaless-like 4

1

20

High-throughput

0.541

High

237275

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.541

High

478358

HXD3
Homeobox protein Hox-D3

1

20

High-throughput

0.541

High

586161

TFE2
Transcription factor E2-alpha

1

6

High-throughput

0.541

High

724909

HXA2
Homeobox protein Hox-A2

1

17

High-throughput

0.541

High

946352

FOXP1
Forkhead box protein P1

1

20

High-throughput

0.541

High

1059046

NFE2
Transcription factor NF-E2 45 kDa subunit

1

5

High-throughput

0.541

High

1189927

Q3U4B1
Single stranded DNA binding protein 4

1

6

High-throughput

0.541

High

1222988

EWS
RNA-binding protein EWS

1

14

High-throughput

0.541

High

1247723

MAML1
Mastermind-like protein 1

1

18

High-throughput

0.541

High

1423947

SSBP3
Single-stranded DNA-binding protein 3

1

4

High-throughput

0.541

High

1424316

WWTR1
WW domain-containing transcription regulator protein 1

1

10

High-throughput

0.541

High

1490157

MIXL1
Homeobox protein MIXL1

1

20

High-throughput

0.541

High

961674

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

0

High-throughput

0.518

High

1490159

CITE4
Cbp/p300-interacting transactivator 4

1

0

High-throughput

0.518

High

1455967

NALP5
NACHT, LRR and PYD domains-containing protein 5

1

4

Small-scale

0.484

High

63119

A5D6Q2
Nuclear receptor coactivator 3

1

17

High-throughput

0.481

High

1190756

Q3UQ14
Zinc finger protein 275

1

1

High-throughput

0.481

High

661121

IRF8
Interferon regulatory factor 8

1

3

High-throughput

0.479

High

108283

G3X904
Zinc finger protein 275

1

1

High-throughput

0.457

High

1053224

Q05BA5
Nuclear receptor coactivator

1

17

High-throughput

0.457

High

1423842

KHDC3
KH domain-containing protein 3

1

3

Small-scale

0.445

High

1296674

ZN473
Zinc finger protein 473 homolog

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025