Protein: RAG1
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]

Gene: RAG1
Organism: Homo sapiens
Interactions: 43
UniProt ID: P15918

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0002331 - pre-B cell allelic exclusion
GO:0003677 - DNA binding
GO:0004519 - endonuclease activity
GO:0004842 - ubiquitin-protein transferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

551431

RAG2
V(D)J recombination-activating protein 2

6

1

Small-scale

0.941

High

551434

UB2D2
Ubiquitin-conjugating enzyme E2 D2

4

20

Small-scale

0.888

High

551422

RAG1
V(D)J recombination-activating protein 1

2

17

Small-scale

0.778

High

551428

UB2D1
Ubiquitin-conjugating enzyme E2 D1

2

20

Small-scale

0.778

High

551432

UBE2H
Ubiquitin-conjugating enzyme E2 H

2

20

Small-scale

0.778

High

551430

IMA5
Importin subunit alpha-5

3

12

Small-scale

0.682

High

135920

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

Small-scale

0.647

High

475309

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

20

Small-scale

0.647

High

551427

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

20

Small-scale

0.647

High

551443

H31T
Histone H3.1t

1

9

Small-scale

0.589

High

551453

DCAF1
DDB1- and CUL4-associated factor 1

1

15

Small-scale

0.586

High

551439

CUL4A
Cullin-4A

2

20

Small-scale

0.584

High

551429

IMA1
Importin subunit alpha-1

2

12

Small-scale

0.584

High

551442

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.536

High

551448

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.515

High

386036

P53
Cellular tumor antigen p53

1

14

Small-scale

0.501

High

394057

A4
Amyloid-beta precursor protein

1

11

High-throughput

0.501

High

449522

HMGB1
High mobility group protein B1

1

14

Small-scale

0.501

High

551425

HMGB2
High mobility group protein B2

1

16

Small-scale

0.501

High

551433

H4
Histone H4

1

4

Small-scale

0.501

High

551436

H31
Histone H3.1

1

9

Small-scale

0.501

High

551444

H2A2C
Histone H2A type 2-C

1

6

Small-scale

0.501

High

551445

H2B2E
Histone H2B type 2-E

1

6

Small-scale

0.501

High

73112

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

4

High-throughput

0.479

High

148358

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.479

High

431502

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

437864

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

551423

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.479

High

551426

CRK
Adapter molecule crk

1

20

High-throughput

0.479

High

551435

RBX1
E3 ubiquitin-protein ligase RBX1

1

3

Small-scale

0.479

High

551437

RUNX1
Runt-related transcription factor 1

1

2

Small-scale

0.479

High

551438

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

6

High-throughput

0.479

High

551440

MDC1
Mediator of DNA damage checkpoint protein 1

1

12

Small-scale

0.479

High

551441

TEBP
Prostaglandin E synthase 3

1

2

High-throughput

0.479

High

551450

Q9BPW0
Serine/threonine-protein phosphatase

1

12

High-throughput

0.479

High

551451

CYBP
Calcyclin-binding protein

1

4

High-throughput

0.479

High

551452

NUDC
Nuclear migration protein nudC

1

6

High-throughput

0.479

High

345841

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.445

High

551424

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

4

High-throughput

0.437

High

551446

Q6PK50
Heat shock protein HSP 90-beta

1

20

High-throughput

0.437

High

551447

NUDC3
NudC domain-containing protein 3

1

6

High-throughput

0.437

High

551449

Q96BE0
Heat shock cognate 71 kDa protein

1

18

High-throughput

0.437

High


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024