Protein: BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1 (hBUB1) (EC 2.7.11.1) (BUB1A)

Gene: BUB1
Organism: Homo sapiens
Interactions: 133
UniProt ID: O43683

Gene Ontology (top 5):
GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

210957

BUB3
Mitotic checkpoint protein BUB3

10

13

Small-scale

0.978

High

211008

CDC20
Cell division cycle protein 20 homolog

11

17

Small-scale

0.978

High

210960

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

8

20

Small-scale

0.968

High

211001

RAE1L
mRNA export factor RAE1

4

12

Small-scale

0.895

High

211040

KNL1
Kinetochore scaffold 1

11

1

Small-scale

0.758

High

211063

MIS12
Protein MIS12 homolog

6

1

Small-scale

0.730

High

210996

PLK1
Serine/threonine-protein kinase PLK1

1

19

Small-scale

0.724

High

210961

CC14B
Dual specificity protein phosphatase CDC14B

1

10

High-throughput

0.698

High

210965

ZN189
Zinc finger protein 189

1

2

High-throughput

0.698

High

210973

RASH
GTPase HRas

1

7

High-throughput

0.698

High

210982

RASA1
Ras GTPase-activating protein 1

1

16

High-throughput

0.698

High

210989

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

High-throughput

0.698

High

210994

CDK8
Cyclin-dependent kinase 8

1

16

High-throughput

0.698

High

211004

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

20

High-throughput

0.698

High

211051

CANB2
Calcineurin subunit B type 2

1

18

High-throughput

0.698

High

211059

TBD2A
TBC1 domain family member 2A

1

14

High-throughput

0.698

High

211077

ZN510
Zinc finger protein 510

1

1

High-throughput

0.698

High

210969

ARI2
E3 ubiquitin-protein ligase ARIH2

4

7

High-throughput

0.692

High

210962

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

1

6

High-throughput

0.691

High

210984

CDK2
Cyclin-dependent kinase 2

1

10

High-throughput

0.691

High

211047

SEH1
Nucleoporin SEH1

1

4

High-throughput

0.691

High

211058

DUS16
Dual specificity protein phosphatase 16

1

3

High-throughput

0.691

High

211072

APC4
Anaphase-promoting complex subunit 4

1

2

High-throughput

0.691

High

154894

NDC80
Kinetochore protein NDC80 homolog

3

18

High-throughput

0.671

High

210998

MLF1
Myeloid leukemia factor 1

3

1

High-throughput

0.667

High

210956

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

18

High-throughput

0.665

High

210964

FRAT2
GSK-3-binding protein FRAT2

1

0

High-throughput

0.663

High

210976

CDK1
Cyclin-dependent kinase 1

1

10

Small-scale

0.647

High

210979

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

12

High-throughput

0.647

High

210995

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2

2

3

High-throughput

0.628

High

211010

CDC16
Cell division cycle protein 16 homolog

2

16

High-throughput

0.628

High

211026

TSTD2
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

1

1

High-throughput

0.625

High

211044

COR2A
Coronin-2A

1

6

High-throughput

0.625

High

211050

NSL1
Kinetochore-associated protein NSL1 homolog

3

0

Small-scale

0.622

High

210967

ZWINT
ZW10 interactor

2

1

High-throughput

0.621

High

210986

MK03
Mitogen-activated protein kinase 3

1

17

High-throughput

0.621

High

210993

CRK
Adapter molecule crk

2

20

High-throughput

0.619

High

211012

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

13

High-throughput

0.618

High

211033

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.618

High

211045

RBPMS
RNA-binding protein with multiple splicing

1

1

High-throughput

0.618

High

211073

ANC2
Anaphase-promoting complex subunit 2

1

14

High-throughput

0.618

High

211075

FZR1
Fizzy-related protein homolog

1

17

High-throughput

0.618

High

211007

BPTF
Nucleosome-remodeling factor subunit BPTF

2

14

High-throughput

0.611

High

211013

HDAC1
Histone deacetylase 1

2

8

Small-scale

0.611

High

211028

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.602

High

210966

UBR5
E3 ubiquitin-protein ligase UBR5

2

20

Small-scale

0.601

High

211021

MAPK3
MAP kinase-activated protein kinase 3

1

18

High-throughput

0.590

High

211036

NKAP
NF-kappa-B-activating protein

2

2

Small-scale

0.584

High

73298

B4E3T4
HCG2043421, isoform CRA_c

1

1

High-throughput

0.575

High

210958

PRKY
Putative serine/threonine-protein kinase PRKY

1

20

High-throughput

0.575

High

211011

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

2

9

Small-scale

0.563

High

210985

APC
Adenomatous polyposis coli protein

1

9

Small-scale

0.561

High

211062

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

8

High-throughput

0.561

High

135882

F16P2
Fructose-1,6-bisphosphatase isozyme 2

1

3

High-throughput

0.541

High

150654

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

20

High-throughput

0.541

High

210974

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

2

High-throughput

0.541

High

210975

ALDOB
Fructose-bisphosphate aldolase B

1

1

High-throughput

0.541

High

210977

F16P1
Fructose-1,6-bisphosphatase 1

1

3

High-throughput

0.541

High

210981

IBP3
Insulin-like growth factor-binding protein 3

1

1

High-throughput

0.541

High

210983

XPA
DNA repair protein complementing XP-A cells

1

1

High-throughput

0.541

High

210987

TMOD1
Tropomodulin-1

1

3

High-throughput

0.541

High

210988

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.541

High

210991

DHB3
17-beta-hydroxysteroid dehydrogenase type 3

1

2

High-throughput

0.541

High

210997

STX17
Syntaxin-17

1

1

High-throughput

0.541

High

210999

SC61B
Protein transport protein Sec61 subunit beta

1

1

High-throughput

0.541

High

211000

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

18

High-throughput

0.541

High

211015

BAAT
Bile acid-CoA:amino acid N-acyltransferase

1

1

High-throughput

0.541

High

211016

CYLC2
Cylicin-2

1

1

High-throughput

0.541

High

211019

SMAD1
Mothers against decapentaplegic homolog 1

1

1

High-throughput

0.541

High

211027

SFRP4
Secreted frizzled-related protein 4

1

3

High-throughput

0.541

High

211037

AMPO
Aminopeptidase O

1

2

High-throughput

0.541

High

211043

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

7

High-throughput

0.541

High

211057

HEMGN
Hemogen

1

1

High-throughput

0.541

High

211068

SIAS
Sialic acid synthase

1

1

High-throughput

0.541

High

211071

LEF1
Lymphoid enhancer-binding factor 1

1

9

High-throughput

0.541

High

210971

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.536

High

210992

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.536

High

211014

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.536

High

211018

PLEC
Plectin

1

6

High-throughput

0.536

High

211022

KI26B
Kinesin-like protein KIF26B

1

9

High-throughput

0.536

High

211053

TCPQM
T-complex protein 1 subunit theta-like 2

1

1

High-throughput

0.536

High

211055

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.536

High

211069

CARF
CDKN2A-interacting protein

1

1

High-throughput

0.536

High

211002

FANCC
Fanconi anemia group C protein

1

0

High-throughput

0.518

High

211060

NUF2
Kinetochore protein Nuf2

1

9

High-throughput

0.515

High

211065

DSN1
Kinetochore-associated protein DSN1 homolog

1

1

High-throughput

0.515

High

211067

SPC25
Kinetochore protein Spc25

1

1

High-throughput

0.515

High

211003

HSF1
Heat shock factor protein 1

1

0

High-throughput

0.513

High

211076

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.513

High

211064

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

8

High-throughput

0.501

High

211078

FBX7
F-box only protein 7

1

2

High-throughput

0.501

High

211035

TEFF1
Tomoregulin-1

1

5

High-throughput

0.494

High

211041

TDRD7
Tudor domain-containing protein 7

1

3

High-throughput

0.494

High

211049

SFRP2
Secreted frizzled-related protein 2

1

3

High-throughput

0.494

High

211052

RDH12
Retinol dehydrogenase 12

1

3

High-throughput

0.494

High

211056

TRMO
tRNA

1

1

High-throughput

0.494

High

211039

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.493

High

211080

TX264
Testis-expressed protein 264

1

0

High-throughput

0.493

High

210978

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

1

High-throughput

0.489

High

210970

SVIL
Supervillin

1

3

Small-scale

0.481

High

210959

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.479

High

210968

KI20A
Kinesin-like protein KIF20A

1

9

High-throughput

0.479

High

210980

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

210990

RFA3
Replication protein A 14 kDa subunit

1

9

High-throughput

0.479

High

211005

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

1

High-throughput

0.479

High

211009

TP53B
TP53-binding protein 1

1

5

Small-scale

0.479

High

211020

ZYX
Zyxin

1

20

High-throughput

0.479

High

211025

NKAPL
NKAP-like protein

1

2

High-throughput

0.479

High

211029

PMF1
Polyamine-modulated factor 1

1

1

High-throughput

0.479

High

211046

PF21A
PHD finger protein 21A

1

5

High-throughput

0.479

High

211054

CK5P2
CDK5 regulatory subunit-associated protein 2

1

17

High-throughput

0.479

High

211074

RCOR1
REST corepressor 1

1

8

High-throughput

0.479

High

211024

RABL6
Rab-like protein 6

1

0

High-throughput

0.458

High

211042

RTF1
RNA polymerase-associated protein RTF1 homolog

1

0

High-throughput

0.458

High

211066

FA83D
Protein FAM83D

1

0

High-throughput

0.458

High

119891

AP3B1
AP-3 complex subunit beta-1

1

10

Small-scale

0.457

High

211006

AP1B1
AP-1 complex subunit beta-1

1

10

Small-scale

0.457

High

211079

AP4B1
AP-4 complex subunit beta-1

1

11

Small-scale

0.457

High

210972

MYC
Myc proto-oncogene protein

1

17

High-throughput

0.445

High

211017

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.445

High

73210

B4DZK1
cDNA FLJ50036, weakly similar to Myosin-11

1

1

High-throughput

0.439

High

118127

HAX1
HCLS1-associated protein X-1

1

2

High-throughput

0.437

High

211030

FBX42
F-box only protein 42

1

6

High-throughput

0.437

High

211070

CC180
Coiled-coil domain-containing protein 180

1

1

High-throughput

0.417

High

211032

BRNP3
BMP/retinoic acid-inducible neural-specific protein 3

2

0

High-throughput

0.328

High

210963

CATL2
Cathepsin L2

1

0

High-throughput

0.282

High

211034

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

0

High-throughput

0.282

High

211048

MSD3
Myb/SANT-like DNA-binding domain-containing protein 3

1

0

High-throughput

0.282

High

211023

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

211038

PRLD2
PRELI domain-containing protein 2

1

0

High-throughput

0.279

Low

211061

RPB1B
DNA-directed RNA polymerase II subunit RPB11-b1

1

0

High-throughput

0.279

Low

211031

CF161
Cilia- and flagella-associated protein 161

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024