HitPredict
Protein: PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Phosphatase and tensin homolog)

Gene: PTEN
Organism: Rattus norvegicus
Interactions: 11
UniProt ID: O54857

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0002902 - regulation of B cell apoptotic process
GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

236501

 NEDD4
E3 ubiquitin-protein ligase NEDD4

2

12

Small-scale

 0.584

High

236498

 DLG4
Disks large homolog 4

1

5

Small-scale

 0.536

High

76701

 B4F767
E3 ubiquitin-protein ligase

1

12

Small-scale

 0.479

High

236497

 5HT2C
5-hydroxytryptamine receptor 2C

1

1

Small-scale

 0.479

High

236499

 CSK
Tyrosine-protein kinase CSK

1

9

Small-scale

 0.479

High

236500

 DREB
Drebrin

1

5

Small-scale

 0.479

High

236502

 UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]

1

3

Small-scale

 0.479

High

236503

 SRC
Proto-oncogene tyrosine-protein kinase Src

1

9

Small-scale

 0.479

High

236496

 CXA1
Gap junction alpha-1 protein

1

0

Small-scale

 0.458

High

236495

 MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

10

Small-scale

 0.445

High

236504

 PARD3
Partitioning defective 3 homolog

1

9

Small-scale

 0.408

High

Service provided by Combinatics, Japan

Last updated: 11Aug2025