Interactor 1: PTEN (O54857)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Phosphatase and tensin homolog)
Gene: PTEN

Interactor 2: CSK (P32577)
Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase)
Gene: CSK

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 27391443
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0008285 - negative regulation of cell population proliferation
GO:0050765 - negative regulation of phagocytosis
GO:0060368 - regulation of Fc receptor mediated stimulatory signaling pathway
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 403
Rn

1 450
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025