Protein: GRM5
Metabotropic glutamate receptor 5 (mGluR5)

Gene: GRM5
Organism: Rattus norvegicus
Interactions: 12
UniProt ID: P31424

Gene Ontology (top 5):
GO:0001639 - PLC activating G protein-coupled glutamate receptor activity
GO:0001640 - adenylate cyclase inhibiting G protein-coupled glutamate receptor activity
GO:0002029 - desensitization of G protein-coupled receptor signaling pathway
GO:0004930 - G protein-coupled receptor activity
GO:0005516 - calmodulin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

726631

GRASP
General receptor for phosphoinositides 1-associated scaffold protein

2

14

Small-scale

0.644

High

726630

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

18

Small-scale

0.618

High

76706

B4F775
Golgi-associated PDZ and coiled-coil motif-containing protein

1

14

Small-scale

0.561

High

726628

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

2

Small-scale

0.529

High

720592

AA2AR
Adenosine receptor A2a

1

5

Small-scale

0.515

High

726633

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

6

Small-scale

0.501

High

726632

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

Small-scale

0.481

High

98611

NECA2
N-terminal EF-hand calcium-binding protein 2

1

1

Small-scale

0.479

High

312181

MAGI2
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

1

16

Small-scale

0.479

High

726629

FAK2
Protein-tyrosine kinase 2-beta

1

11

Small-scale

0.479

High

726634

ACTN1
Alpha-actinin-1

1

3

Small-scale

0.479

High

726635

HOME1
Homer protein homolog 1

1

10

Small-scale

0.457

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025