HitPredict - High confidence protein-protein interactions

Protein: FAK2
Protein-tyrosine kinase 2-beta (EC 2.7.10.2) (Calcium-dependent tyrosine kinase) (CADTK) (Calcium-regulated non-receptor proline-rich tyrosine kinase) (Cell adhesion kinase beta) (CAK-beta) (CAKB) (Focal adhesion kinase 2) (FADK 2) (Proline-rich tyrosine kinase 2)

Gene: FAK2, Ptk2b
Organism: Rattus norvegicus
Interactions: 9
UniProt ID: P70600

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0000302 - response to reactive oxygen species
GO:0001525 - angiogenesis
GO:0001556 - oocyte maturation
GO:0001666 - response to hypoxia

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
1000485	FAK2 Protein-tyrosine kinase 2-beta	1	20	Small-scale	0.647	High
989595	MK01 Mitogen-activated protein kinase 1	1	5	High-throughput	0.618	High
1000487	AKT3 RAC-gamma serine/threonine-protein kinase	1	20	High-throughput	0.618	High
1000488	SRC Proto-oncogene tyrosine-protein kinase Src	1	20	Small-scale	0.618	High
657946	GRM1 Metabotropic glutamate receptor 1	1	8	Small-scale	0.479	High
726629	GRM5 Metabotropic glutamate receptor 5	1	11	Small-scale	0.479	High
1000470	PLD2 Phospholipase D2	1	3	Small-scale	0.479	High
1000486	ARFG1 ADP-ribosylation factor GTPase-activating protein 1	1	20	Small-scale	0.479	High

Service provided by Combinatics, Japan

Last updated: 11Aug2025