Protein: LYPD3
Ly6/PLAUR domain-containing protein 3 (GPI-anchored metastasis-associated protein C4.4A homolog) (Matrigel-induced gene C4 protein) (MIG-C4)

Gene: LYPD3
Organism: Homo sapiens
Interactions: 139
UniProt ID: O95274

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0007160 - cell-matrix adhesion
GO:0034392 - negative regulation of smooth muscle cell apoptotic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168314

SCAM1
Secretory carrier-associated membrane protein 1

3

1

High-throughput

0.667

High

310264

AT2B4
Plasma membrane calcium-transporting ATPase 4

3

1

High-throughput

0.667

High

310274

CKAP4
Cytoskeleton-associated protein 4

3

1

High-throughput

0.667

High

310289

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

3

1

High-throughput

0.667

High

254532

CLAP2
CLIP-associating protein 2

3

2

High-throughput

0.656

High

172548

GNPAT
Dihydroxyacetone phosphate acyltransferase

3

0

High-throughput

0.638

High

300550

ENDD1
Endonuclease domain-containing 1 protein

3

0

High-throughput

0.638

High

310263

SL9A1
Sodium/hydrogen exchanger 1

3

0

High-throughput

0.638

High

310271

ARFP2
Arfaptin-2

3

0

High-throughput

0.638

High

310284

SLMAP
Sarcolemmal membrane-associated protein

3

0

High-throughput

0.638

High

310301

NCEH1
Neutral cholesterol ester hydrolase 1

3

0

High-throughput

0.638

High

310311

LAP4B
Lysosomal-associated transmembrane protein 4B

3

0

High-throughput

0.638

High

310314

C2CD5
C2 domain-containing protein 5

3

0

High-throughput

0.638

High

310316

S41A1
Solute carrier family 41 member 1

3

0

High-throughput

0.638

High

310327

CTL1
Choline transporter-like protein 1

3

0

High-throughput

0.638

High

310329

LPAR1
Lysophosphatidic acid receptor 1

3

0

High-throughput

0.638

High

310332

SYMPK
Symplekin

3

0

High-throughput

0.638

High

310339

XPO6
Exportin-6

3

0

High-throughput

0.638

High

310349

PIGU
Phosphatidylinositol glycan anchor biosynthesis class U protein

3

0

High-throughput

0.638

High

310359

COMD9
COMM domain-containing protein 9

3

0

High-throughput

0.638

High

310365

DYN3
Dynamin-3

3

0

High-throughput

0.638

High

310369

FLVC1
Heme transporter FLVCR1

3

0

High-throughput

0.638

High

126500

QSOX1
Sulfhydryl oxidase 1

2

1

High-throughput

0.611

High

310269

CLCN3
H(+)/Cl(-) exchange transporter 3

2

1

High-throughput

0.611

High

310265

COT2
COUP transcription factor 2

3

1

High-throughput

0.609

High

310268

MTOR
Serine/threonine-protein kinase mTOR

3

1

High-throughput

0.609

High

310270

CLCN7
H(+)/Cl(-) exchange transporter 7

3

1

High-throughput

0.609

High

310281

ATR
Serine/threonine-protein kinase ATR

3

1

High-throughput

0.609

High

310291

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

3

1

High-throughput

0.609

High

310310

GLT10
Polypeptide N-acetylgalactosaminyltransferase 10

3

1

High-throughput

0.609

High

310318

PHTF2
Protein PHTF2

3

1

High-throughput

0.609

High

310334

FAKD4
FAST kinase domain-containing protein 4

3

2

High-throughput

0.609

High

310356

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

3

1

High-throughput

0.609

High

310361

XPO7
Exportin-7

3

2

High-throughput

0.609

High

310364

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

3

2

High-throughput

0.609

High

310368

TNPO3
Transportin-3

3

2

High-throughput

0.609

High

310372

5MP1
eIF5-mimic protein 1

3

1

High-throughput

0.609

High

155501

TNPO2
Transportin-2

3

1

High-throughput

0.599

High

255267

HIP1R
Huntingtin-interacting protein 1-related protein

2

0

High-throughput

0.585

High

310255

AGR2
Anterior gradient protein 2 homolog

2

1

Small-scale

0.584

High

310262

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

1

High-throughput

0.558

High

310295

ECM29
Proteasome adapter and scaffold protein ECM29

2

3

High-throughput

0.558

High

310358

FAKD2
FAST kinase domain-containing protein 2, mitochondrial

2

2

High-throughput

0.558

High

310260

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

2

High-throughput

0.541

High

310276

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

1

High-throughput

0.541

High

310254

BAG4
BAG family molecular chaperone regulator 4

1

0

High-throughput

0.518

High

310261

IGF1R
Insulin-like growth factor 1 receptor

1

0

High-throughput

0.518

High

310266

LSP1
Lymphocyte-specific protein 1

1

0

High-throughput

0.518

High

310278

MSLN
Mesothelin

1

0

High-throughput

0.513

High

310306

TMC4
Transmembrane channel-like protein 4

1

0

High-throughput

0.513

High

310341

CIB1
Calcium and integrin-binding protein 1

1

0

High-throughput

0.513

High

310346

T126A
Transmembrane protein 126A

1

0

High-throughput

0.513

High

156431

SCAM3
Secretory carrier-associated membrane protein 3

1

1

High-throughput

0.489

High

310272

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

1

High-throughput

0.489

High

310317

TEX14
Inactive serine/threonine-protein kinase TEX14

1

3

High-throughput

0.489

High

310362

PHTF1
Protein PHTF1

1

1

High-throughput

0.489

High

310282

CKAP5
Cytoskeleton-associated protein 5

1

2

High-throughput

0.479

High

310304

QSOX2
Sulfhydryl oxidase 2

1

1

High-throughput

0.479

High

310320

AT11C
Phospholipid-transporting ATPase IG

1

0

High-throughput

0.458

High

310325

GDPD5
Glycerophosphodiester phosphodiesterase domain-containing protein 5

1

0

High-throughput

0.458

High

310343

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.458

High

310323

AGR3
Anterior gradient protein 3

1

1

Small-scale

0.439

High

163547

BTAF1
TATA-binding protein-associated factor 172

1

1

High-throughput

0.437

High

308281

KI20A
Kinesin-like protein KIF20A

1

4

High-throughput

0.437

High

310256

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

1

High-throughput

0.437

High

310273

KIF23
Kinesin-like protein KIF23

1

2

High-throughput

0.437

High

310286

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.437

High

310305

5MP2
eIF5-mimic protein 2

1

1

High-throughput

0.437

High

310331

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

310367

VDAC3
Voltage-dependent anion-selective channel protein 3

1

1

High-throughput

0.437

High

91241

E3W994
Cytoplasmic linker associated protein 2

1

2

High-throughput

0.407

High

310292

Q4LE60
TNPO2 variant protein

1

1

High-throughput

0.407

High

199992

GPAA1
Glycosylphosphatidylinositol anchor attachment 1 protein

3

0

High-throughput

0.347

High

215178

STRN
Striatin

3

0

High-throughput

0.347

High

217220

ORC5
Origin recognition complex subunit 5

3

0

High-throughput

0.347

High

310275

TMM94
Transmembrane protein 94

3

0

High-throughput

0.347

High

310277

TARB1
Probable methyltransferase TARBP1

3

0

High-throughput

0.347

High

310280

MTX1
Metaxin-1

3

0

High-throughput

0.347

High

310290

D19L1
Protein C-mannosyl-transferase DPY19L1

3

0

High-throughput

0.347

High

310293

MKS3
Meckelin

3

0

High-throughput

0.347

High

310297

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

3

0

High-throughput

0.347

High

310298

MYORG
Myogenesis-regulating glycosidase

3

0

High-throughput

0.347

High

310299

TM214
Transmembrane protein 214

3

0

High-throughput

0.347

High

310308

UB2Q1
Ubiquitin-conjugating enzyme E2 Q1

3

0

High-throughput

0.347

High

310326

LMBR1
Limb region 1 protein homolog

3

0

High-throughput

0.347

High

310328

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

3

0

High-throughput

0.347

High

310335

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

3

0

High-throughput

0.347

High

310338

BOD1
Biorientation of chromosomes in cell division protein 1

3

0

High-throughput

0.347

High

310347

TM245
Transmembrane protein 245

3

0

High-throughput

0.347

High

310348

GHITM
Growth hormone-inducible transmembrane protein

3

0

High-throughput

0.347

High

310355

HELLS
Lymphoid-specific helicase

3

0

High-throughput

0.347

High

310357

CLDN1
Claudin domain-containing protein 1

3

0

High-throughput

0.347

High

310363

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

3

0

High-throughput

0.347

High

310366

PLAP
Phospholipase A-2-activating protein

3

0

High-throughput

0.347

High

310370

SPCS1
Signal peptidase complex subunit 1

3

0

High-throughput

0.347

High

310351

REEP1
Receptor expression-enhancing protein 1

2

0

High-throughput

0.328

High

147044

NEMP1
Nuclear envelope integral membrane protein 1

2

0

High-throughput

0.318

High

310300

TTI2
TELO2-interacting protein 2

2

0

High-throughput

0.318

High

310307

HEAT3
HEAT repeat-containing protein 3

2

0

High-throughput

0.318

High

310315

TPPC5
Trafficking protein particle complex subunit 5

2

0

High-throughput

0.318

High

310321

ZNT7
Zinc transporter 7

2

0

High-throughput

0.318

High

310330

GPI8
GPI-anchor transamidase

2

0

High-throughput

0.318

High

310340

PIGS
GPI transamidase component PIG-S

2

0

High-throughput

0.318

High

310342

DCNL5
DCN1-like protein 5

2

0

High-throughput

0.318

High

310344

LNP
Endoplasmic reticulum junction formation protein lunapark

2

0

High-throughput

0.318

High

310345

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.318

High

310371

MTCH2
Mitochondrial carrier homolog 2

2

0

High-throughput

0.318

High

160302

AURKA
Aurora kinase A

1

0

High-throughput

0.282

High

175360

PPM1D
Protein phosphatase 1D

1

0

High-throughput

0.282

High

310258

CHK2
Serine/threonine-protein kinase Chk2

1

0

High-throughput

0.282

High

310279

SMAD4
Mothers against decapentaplegic homolog 4

1

0

High-throughput

0.282

High

310283

CASP8
Caspase-8

1

0

High-throughput

0.282

High

310288

STK11
Serine/threonine-protein kinase STK11

1

0

High-throughput

0.282

High

310313

PALB2
Partner and localizer of BRCA2

1

0

High-throughput

0.282

High

310324

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.282

High

310352

BRMS1
Breast cancer metastasis-suppressor 1

1

0

High-throughput

0.282

High

310257

PX11B
Peroxisomal membrane protein 11B

1

0

High-throughput

0.279

Low

310259

MOS
Proto-oncogene serine/threonine-protein kinase mos

1

0

High-throughput

0.279

Low

310287

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

1

0

High-throughput

0.279

Low

310296

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.279

Low

310309

PCGF5
Polycomb group RING finger protein 5

1

0

High-throughput

0.279

Low

310319

DJC22
DnaJ homolog subfamily C member 22

1

0

High-throughput

0.279

Low

310333

PIGT
GPI transamidase component PIG-T

1

0

High-throughput

0.279

Low

310337

BORC6
BLOC-1-related complex subunit 6

1

0

High-throughput

0.279

Low

208698

TPPC3
Trafficking protein particle complex subunit 3

1

0

High-throughput

0.249

Low

226135

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.249

Low

281488

WFS1
Wolframin

1

0

High-throughput

0.249

Low

310267

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

0

High-throughput

0.249

Low

310285

CND1
Condensin complex subunit 1

1

0

High-throughput

0.249

Low

310294

RBM26
RNA-binding protein 26

1

0

High-throughput

0.249

Low

310302

BRAT1
BRCA1-associated ATM activator 1

1

0

High-throughput

0.249

Low

310303

THADA
tRNA

1

0

High-throughput

0.249

Low

310312

DAAF5
Dynein axonemal assembly factor 5

1

0

High-throughput

0.249

Low

310322

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

High-throughput

0.249

Low

310336

RUSF1
RUS family member 1

1

0

High-throughput

0.249

Low

310350

ECT2
Protein ECT2

1

0

High-throughput

0.249

Low

310353

ANLN
Anillin

1

0

High-throughput

0.249

Low

310354

AAAS
Aladin

1

0

High-throughput

0.249

Low

310360

HDAC6
Histone deacetylase 6

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024