Protein: TOP3B
DNA topoisomerase 3-beta (EC 5.6.2.1) (DNA topoisomerase III beta)

Gene: TOP3B, Top3beta
Organism: Drosophila melanogaster
Interactions: 12
UniProt ID: O96651

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003917 - DNA topoisomerase type I (single strand cut, ATP-independent) activity
GO:0005634 - nucleus
GO:0006265 - DNA topological change
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

355848

Q9VUH8
Survival of motor neuron-related-splicing factor 30

4

4

Small-scale

0.867

High

355840

DDX17
ATP-dependent RNA helicase p62

1

1

Small-scale

0.618

High

355845

FMR1
Fragile X messenger ribonucleoprotein 1 homolog

2

6

Small-scale

0.584

High

355844

Q8MRH0
RE37229p

1

1

High-throughput

0.445

High

355849

Q9VZF5
Kinesin-like protein

1

2

High-throughput

0.445

High

355841

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.426

High

355843

Q7KNS5
Quaking related 54B, isoform A

1

0

High-throughput

0.426

High

355847

Q9VNV0
non-specific serine/threonine protein kinase

1

0

High-throughput

0.426

High

355850

ZN593
Zinc finger protein 593 homolog

1

0

High-throughput

0.426

High

84262

B6VQA0
Transcription factor BTF3

1

1

High-throughput

0.407

High

355846

Q9VI39
AT17667p

1

0

High-throughput

0.251

Low

355842

Q7JRH5
RE28271p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025