Interactor 1: TOP3B (O96651)
DNA topoisomerase 3-beta (EC 5.6.2.1) (DNA topoisomerase III beta)
Gene: Top3beta

Interactor 2: Q9VUH8 (Q9VUH8)
Survival of motor neuron-related-splicing factor 30 (Survival motor neuron domain-containing protein 1) (Tudor domain-containing protein 3)
Gene: Tdrd3

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.867

The method score is based on:

Property Details
Experiments 23912945, 30470739, 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RMI1_N_C~Topoisom_bac
Common GO terms GO:0005634 - nucleus
GO:0006265 - DNA topological change
GO:0140225 - DNA topoisomerase III-beta-TDRD3 complex
GO:0141194 - siRNA-mediated heterochromatin formation
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 875
Dm

1 836
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025