Protein: PGL3
Guanyl-specific ribonuclease pgl-3 (EC 4.6.1.24) (P granule abnormality protein 3)

Gene: PGL3, pgl-3
Organism: Caenorhabditis elegans
Interactions: 51
UniProt ID: G5EBV6

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0004521 - RNA endonuclease activity
GO:0016829 - lyase activity
GO:0042802 - identical protein binding
GO:0043186 - P granule

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

110198

PGL1
Guanyl-specific ribonuclease pgl-1

2

4

Small-scale

0.620

High

110196

Q9TXM1
Uncharacterized protein

2

2

Small-scale

0.595

High

110189

TOR
Target of rapamycin homolog

1

1

Small-scale

0.512

High

110199

ANM1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.512

High

110153

PGL3
Guanyl-specific ribonuclease pgl-3

1

4

Small-scale

0.501

High

110165

IF4E1
Eukaryotic translation initiation factor 4E-1

1

1

High-throughput

0.479

High

110166

WAGO4
Argonaute protein wago-4

1

2

High-throughput

0.479

High

110169

PGL2
P granule abnormality protein 2

1

4

Small-scale

0.479

High

110181

WAGO1
Argonaute protein wago-1

1

2

High-throughput

0.479

High

110194

Q9N585
Piwi domain-containing protein

1

2

High-throughput

0.479

High

110170

YO61
WW domain-containing protein ZK1098.1

1

0

High-throughput

0.458

High

110173

P90786
Piwi-like protein 1

1

0

High-throughput

0.458

High

110154

SEPA1
Protein sepa-1

3

0

Small-scale

0.351

High

110183

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.282

High

90933

C6KRI9
Kinesin motor domain-containing protein

1

0

High-throughput

0.249

Low

110155

G5ECS9
Calponin-homology

1

0

High-throughput

0.249

Low

110156

G5EEL9
HMG

1

0

High-throughput

0.249

Low

110157

G5EFX8
Not3 domain-containing protein

1

0

High-throughput

0.249

Low

110158

H2KZK7
Dipeptidyl Peptidase Four

1

0

High-throughput

0.249

Low

110159

O01442
Zf-tcix domain-containing protein

1

0

High-throughput

0.249

Low

110160

O01815
Dihydroorotate dehydrogenase

1

0

High-throughput

0.249

Low

110161

TIM44
Probable mitochondrial import inner membrane translocase subunit tin-44

1

0

High-throughput

0.249

Low

110162

O17626
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.249

Low

110163

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.249

Low

110164

TR112
Multifunctional methyltransferase subunit TRM112-like protein

1

0

High-throughput

0.249

Low

110167

KCC2D
Calcium/calmodulin-dependent protein kinase type II

1

0

High-throughput

0.249

Low

110168

CED4
Cell death protein 4

1

0

High-throughput

0.249

Low

110171

KTNA1
Meiotic spindle formation protein mei-1

1

0

High-throughput

0.249

Low

110172

SDS22
Protein phosphatase 1 regulatory subunit SDS22 homolog

1

0

High-throughput

0.249

Low

110174

CHDP1
Calponin homology domain-containing protein

1

0

High-throughput

0.249

Low

110175

ETFD
Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.249

Low

110176

GSLG1
Golgi apparatus protein 1 homolog

1

0

High-throughput

0.249

Low

110177

SAS5
Spindle assembly abnormal protein 5

1

0

High-throughput

0.249

Low

110178

Q20697
dTDP-D-glucose 4,6-dehydratase

1

0

High-throughput

0.249

Low

110179

Q21501
YEATS domain-containing protein

1

0

High-throughput

0.249

Low

110180

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.249

Low

110182

NAA25
N-terminal acetyltransferase B complex subunit NAA25 homolog

1

0

High-throughput

0.249

Low

110184

Q22935
Uncharacterized protein

1

0

High-throughput

0.249

Low

110185

Q8MXF3
RRM domain-containing protein

1

0

High-throughput

0.249

Low

110186

Q8MXJ7
Aldehyde dehydrogenase

1

0

High-throughput

0.249

Low

110187

Q93338
DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein

1

0

High-throughput

0.249

Low

110188

FAAA
Fumarylacetoacetase

1

0

High-throughput

0.249

Low

110190

SEM2A
Semaphorin-2A

1

0

High-throughput

0.249

Low

110191

EPG2
Ectopic P granules protein 2

1

0

High-throughput

0.249

Low

110192

Q9N302
Long-chain-fatty-acid--CoA ligase

1

0

High-throughput

0.249

Low

110193

FEN1
Flap endonuclease 1

1

0

High-throughput

0.249

Low

110195

Q9N5A2
Piwi domain-containing protein

1

0

High-throughput

0.249

Low

110197

LRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

0

High-throughput

0.249

Low

110200

Q9UB01
WH2 domain-containing protein

1

0

High-throughput

0.249

Low

110201

PP4C1
Serine/threonine-protein phosphatase 4 catalytic subunit 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025