Protein: KCC2D
Calcium/calmodulin-dependent protein kinase type II (CaM kinase II) (EC 2.7.11.17) (Uncoordinated protein 43)

Gene: KCC2D, unc-43
Organism: Caenorhabditis elegans
Interactions: 29
UniProt ID: O62305

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0004683 - calcium/calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

264245

KCC2D
Calcium/calmodulin-dependent protein kinase type II

3

15

Small-scale

0.888

High

264249

MPK1
Mitogen-activated protein kinase mpk-1

3

10

High-throughput

0.847

High

231943

O44164
Potassium voltage-gated channel protein eag

1

16

Small-scale

0.713

High

264255

PMK1
Mitogen-activated protein kinase pmk-1

1

11

High-throughput

0.698

High

264250

FEM2
Protein phosphatase fem-2

1

7

Small-scale

0.647

High

112315

SRC1
Tyrosine protein-kinase src-1

1

15

High-throughput

0.621

High

234030

SRC2
Tyrosine protein-kinase src-2

1

15

High-throughput

0.621

High

264247

PLK1
Serine/threonine-protein kinase plk-1

1

12

High-throughput

0.618

High

264256

SARM1
NAD(+) hydrolase tir-1

1

0

Small-scale

0.586

High

264252

STX4
Putative syntaxin-4

2

5

High-throughput

0.584

High

264258

VATE
V-type proton ATPase subunit E

2

0

High-throughput

0.551

High

264254

PAR3
Partitioning defective protein 3

1

20

High-throughput

0.541

High

195786

FOXO
Forkhead box protein O

1

0

Small-scale

0.537

High

111261

G5ECY7
Calponin-homology

1

13

High-throughput

0.512

High

264257

Q93697
glutathione transferase

1

1

High-throughput

0.512

High

264253

TX1B3
Tax1-binding protein 3 homolog

1

20

High-throughput

0.494

High

110414

G5EC35
Beta chain spectrin homolog Sma1

1

9

High-throughput

0.481

High

114723

H1ZUX3
RING-type domain-containing protein

1

0

High-throughput

0.458

High

264259

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.458

High

114320

CTNL1
Alpha-catulin

1

2

High-throughput

0.439

High

264248

LEC1
32 kDa beta-galactoside-binding lectin

1

2

High-throughput

0.439

High

232294

O44490
ELKS/RAB6-interacting/CAST family member 2

1

5

High-throughput

0.437

High

264251

LIN53
Probable histone-binding protein lin-53

1

1

High-throughput

0.437

High

234345

O45904
Galectin

1

2

High-throughput

0.417

High

195406

O16364
CC domain-containing protein

1

0

High-throughput

0.282

High

264246

KNL1
Outer kinetochore KNL1 complex subunit knl-1

1

0

High-throughput

0.282

High

96225

E9P875
Neurexin-3-beta

1

0

High-throughput

0.249

Low

110167

PGL3
Guanyl-specific ribonuclease pgl-3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025