Protein: ACTZ
Alpha-centractin (Centractin) (ARP1) (Actin-RPV) (Centrosome-associated actin homolog)

Gene: ACTZ, ACTR1A
Organism: Homo sapiens
Interactions: 201
UniProt ID: P61163

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0005869 - dynactin complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897050

DCTN2
Dynactin subunit 2

7

6

High-throughput

0.966

High

812979

CAZA2
F-actin-capping protein subunit alpha-2

4

11

High-throughput

0.903

High

785525

ACTY
Beta-centractin

4

17

High-throughput

0.895

High

897150

DCTN4
Dynactin subunit 4

4

5

Small-scale

0.890

High

897057

DYHC1
Cytoplasmic dynein 1 heavy chain 1

3

4

High-throughput

0.861

High

897139

ARP10
Actin-related protein 10

3

20

Small-scale

0.853

High

813298

CAPZB
F-actin-capping protein subunit beta

2

5

High-throughput

0.811

High

897062

MARE1
Microtubule-associated protein RP/EB family member 1

2

1

High-throughput

0.811

High

164592

SPTN2
Spectrin beta chain, non-erythrocytic 2

2

20

Small-scale

0.804

High

897044

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

2

9

High-throughput

0.789

High

897056

DCTN1
Dynactin subunit 1

5

18

High-throughput

0.718

High

413876

GELS
Gelsolin

1

20

High-throughput

0.691

High

851410

NEK4
Serine/threonine-protein kinase Nek4

1

16

High-throughput

0.691

High

857093

CAZA1
F-actin-capping protein subunit alpha-1

1

11

High-throughput

0.691

High

891655

ACTB
Actin, cytoplasmic 1

1

19

High-throughput

0.691

High

897029

ACTA
Actin, aortic smooth muscle

1

19

High-throughput

0.691

High

897031

ACTG
Actin, cytoplasmic 2

1

19

High-throughput

0.691

High

897033

ACTC
Actin, alpha cardiac muscle 1

1

19

High-throughput

0.665

High

897061

PLEC
Plectin

1

15

High-throughput

0.665

High

897091

BICD2
Protein bicaudal D homolog 2

3

18

Small-scale

0.650

High

528874

CFTR
Cystic fibrosis transmembrane conductance regulator

3

4

High-throughput

0.643

High

126684

DCTN6
Dynactin subunit 6

2

2

High-throughput

0.628

High

148056

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

8

High-throughput

0.618

High

160473

AURKA
Aurora kinase A

1

7

High-throughput

0.618

High

373982

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.618

High

418928

TPM3
Tropomyosin alpha-3 chain

1

12

High-throughput

0.618

High

506560

BCR
Breakpoint cluster region protein

1

12

High-throughput

0.618

High

897032

TPM4
Tropomyosin alpha-4 chain

1

13

High-throughput

0.618

High

897039

TWF1
Twinfilin-1

1

20

High-throughput

0.618

High

897047

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

1

8

High-throughput

0.618

High

897048

KCC2G
Calcium/calmodulin-dependent protein kinase type II subunit gamma

1

7

High-throughput

0.618

High

897049

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

7

High-throughput

0.618

High

897054

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

8

High-throughput

0.618

High

897069

TWF2
Twinfilin-2

1

20

High-throughput

0.618

High

897084

DYH10
Dynein axonemal heavy chain 10

1

4

High-throughput

0.618

High

897140

PD1L1
Programmed cell death 1 ligand 1

1

1

High-throughput

0.618

High

897151

FZR1
Fizzy-related protein homolog

1

7

High-throughput

0.618

High

198238

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

2

4

High-throughput

0.611

High

278597

DCTN3
Dynactin subunit 3

2

3

High-throughput

0.611

High

307162

KLHL2
Kelch-like protein 2

2

9

High-throughput

0.611

High

573198

TCPA
T-complex protein 1 subunit alpha

2

20

High-throughput

0.611

High

770767

TCPZ
T-complex protein 1 subunit zeta

2

20

High-throughput

0.611

High

826597

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.611

High

843135

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.611

High

897035

TCPB
T-complex protein 1 subunit beta

2

20

High-throughput

0.611

High

897053

CUL3
Cullin-3

2

12

High-throughput

0.611

High

897121

PDCL3
Phosducin-like protein 3

2

6

High-throughput

0.611

High

897156

DC1L1
Cytoplasmic dynein 1 light intermediate chain 1

2

4

High-throughput

0.611

High

227036

PRKN
E3 ubiquitin-protein ligase parkin

2

16

High-throughput

0.584

High

684583

STIP1
Stress-induced-phosphoprotein 1

2

8

High-throughput

0.584

High

779138

CCNF
Cyclin-F

2

2

High-throughput

0.584

High

897066

LARP7
La-related protein 7

2

13

High-throughput

0.584

High

897085

NIN
Ninein

2

20

High-throughput

0.584

High

897134

ANLN
Anillin

2

10

High-throughput

0.584

High

897144

HDAC6
Histone deacetylase 6

2

7

Small-scale

0.584

High

897153

NINL
Ninein-like protein

2

16

High-throughput

0.584

High

897067

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

11

High-throughput

0.575

High

369291

ESR1
Estrogen receptor

2

11

High-throughput

0.571

High

592185

RAB5A
Ras-related protein Rab-5A

2

1

High-throughput

0.571

High

897027

WDR5
WD repeat-containing protein 5

1

7

High-throughput

0.553

High

128514

DNM1L
Dynamin-1-like protein

1

2

High-throughput

0.536

High

204487

ARK72
Aflatoxin B1 aldehyde reductase member 2

1

2

High-throughput

0.536

High

254566

CLAP2
CLIP-associating protein 2

1

1

High-throughput

0.536

High

450794

F16P1
Fructose-1,6-bisphosphatase 1

1

2

High-throughput

0.536

High

496704

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.536

High

675146

CLIP1
CAP-Gly domain-containing linker protein 1

1

15

High-throughput

0.536

High

683239

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.536

High

897030

DYL1
Dynein light chain 1, cytoplasmic

1

3

High-throughput

0.536

High

897034

TBB4B
Tubulin beta-4B chain

1

3

High-throughput

0.536

High

897052

CUL1
Cullin-1

1

12

High-throughput

0.536

High

897055

SCRB2
Lysosome membrane protein 2

1

2

High-throughput

0.536

High

897078

CLAP1
CLIP-associating protein 1

1

1

High-throughput

0.536

High

897096

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.536

High

897099

CSN5
COP9 signalosome complex subunit 5

1

8

High-throughput

0.536

High

897104

MERB1
bMERB domain-containing protein 1

1

4

High-throughput

0.536

High

897109

CDC5L
Cell division cycle 5-like protein

1

2

High-throughput

0.536

High

897114

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.536

High

897117

DCTN5
Dynactin subunit 5

1

6

High-throughput

0.536

High

897122

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.536

High

897132

RIC8A
Synembryn-A

1

1

High-throughput

0.536

High

897138

MS18A
Protein Mis18-alpha

1

1

High-throughput

0.536

High

897083

AHNK2
Protein AHNAK2

1

7

High-throughput

0.515

High

897065

INAVA
Innate immunity activator protein

1

0

High-throughput

0.513

High

897051

SNW1
SNW domain-containing protein 1

1

2

High-throughput

0.489

High

897108

IWS1
Protein IWS1 homolog

1

3

High-throughput

0.489

High

897118

TX101
Testis-expressed protein 101

1

3

High-throughput

0.489

High

897119

PDGFD
Platelet-derived growth factor D

1

1

High-throughput

0.489

High

897120

DB127
Beta-defensin 127

1

1

High-throughput

0.489

High

122603

MEN1
Menin

1

1

High-throughput

0.479

High

147233

TXND9
Thioredoxin domain-containing protein 9

1

14

High-throughput

0.479

High

171595

PFD6
Prefoldin subunit 6

1

2

High-throughput

0.479

High

202621

TXNL1
Thioredoxin-like protein 1

1

7

High-throughput

0.479

High

294610

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

298344

UFL1
E3 UFM1-protein ligase 1

1

4

High-throughput

0.479

High

303076

HEXI1
Protein HEXIM1

1

7

High-throughput

0.479

High

311518

SMC2
Structural maintenance of chromosomes protein 2

1

2

High-throughput

0.479

High

323404

TTC4
Tetratricopeptide repeat protein 4

1

12

High-throughput

0.479

High

346386

MYC
Myc proto-oncogene protein

1

7

High-throughput

0.479

High

384589

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.479

High

475554

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

11

High-throughput

0.479

High

503802

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

590765

BTF3
Transcription factor BTF3

1

3

High-throughput

0.479

High

817857

SOX2
Transcription factor SOX-2

1

2

High-throughput

0.479

High

821148

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.479

High

842307

PPT1
Palmitoyl-protein thioesterase 1

1

2

High-throughput

0.479

High

842809

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.479

High

874759

TERA
Transitional endoplasmic reticulum ATPase

1

5

High-throughput

0.479

High

895984

UBC12
NEDD8-conjugating enzyme Ubc12

1

3

High-throughput

0.479

High

897025

RS3A
Small ribosomal subunit protein eS1

1

1

High-throughput

0.479

High

897028

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

897036

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

4

High-throughput

0.479

High

897037

MECOM
Histone-lysine N-methyltransferase MECOM

1

5

High-throughput

0.479

High

897038

ECHP
Peroxisomal bifunctional enzyme

1

7

High-throughput

0.479

High

897041

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

3

Small-scale

0.479

High

897043

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.479

High

897045

BIRC3
Baculoviral IAP repeat-containing protein 3

1

2

High-throughput

0.479

High

897046

SQSTM
Sequestosome-1

1

5

High-throughput

0.479

High

897058

RBM39
RNA-binding protein 39

1

7

High-throughput

0.479

High

897059

NUMA1
Nuclear mitotic apparatus protein 1

1

20

Small-scale

0.479

High

897060

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

897063

CDC37
Hsp90 co-chaperone Cdc37

1

2

High-throughput

0.479

High

897064

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

897068

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

897071

DEN5A
DENN domain-containing protein 5A

1

1

High-throughput

0.479

High

897072

RICTR
Rapamycin-insensitive companion of mTOR

1

1

High-throughput

0.479

High

897073

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.479

High

897074

DEN5B
DENN domain-containing protein 5B

1

1

High-throughput

0.479

High

897075

MOB3C
MOB kinase activator 3C

1

2

High-throughput

0.479

High

897076

SSH2
Protein phosphatase Slingshot homolog 2

1

14

High-throughput

0.479

High

897079

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

5

High-throughput

0.479

High

897080

ZN598
E3 ubiquitin-protein ligase ZNF598

1

5

High-throughput

0.479

High

897082

NUDC3
NudC domain-containing protein 3

1

4

High-throughput

0.479

High

897086

ARFG2
ADP-ribosylation factor GTPase-activating protein 2

1

3

High-throughput

0.479

High

897088

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

897089

CIP2A
Protein CIP2A

1

10

High-throughput

0.479

High

897090

ALMS1
Centrosome-associated protein ALMS1

1

7

High-throughput

0.479

High

897092

RBCC1
RB1-inducible coiled-coil protein 1

1

20

High-throughput

0.479

High

897094

NUDC2
NudC domain-containing protein 2

1

4

High-throughput

0.479

High

897097

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

10

High-throughput

0.479

High

897101

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

3

High-throughput

0.479

High

897103

DYL2
Dynein light chain 2, cytoplasmic

1

3

High-throughput

0.479

High

897111

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.479

High

897112

NECD
Necdin

1

6

High-throughput

0.479

High

897113

TTC1
Tetratricopeptide repeat protein 1

1

11

High-throughput

0.479

High

897116

RIOK1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

897123

CA198
Uncharacterized protein C1orf198

1

1

High-throughput

0.479

High

897124

PKHA4
Pleckstrin homology domain-containing family A member 4

1

15

High-throughput

0.479

High

897125

RPAP3
RNA polymerase II-associated protein 3

1

12

High-throughput

0.479

High

897127

PRD16
Histone-lysine N-methyltransferase PRDM16

1

3

High-throughput

0.479

High

897129

VEZA
Vezatin

1

1

High-throughput

0.479

High

897130

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

High-throughput

0.479

High

897133

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

897135

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.479

High

897137

TBA8
Tubulin alpha-8 chain

1

6

High-throughput

0.479

High

897141

RN181
E3 ubiquitin-protein ligase RNF181

1

1

High-throughput

0.479

High

897145

DUX4
Double homeobox protein 4

1

3

High-throughput

0.479

High

897146

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

897147

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.479

High

897148

DS13B
Dual specificity protein phosphatase 13B

1

16

High-throughput

0.479

High

897149

HOOK1
Protein Hook homolog 1

1

19

High-throughput

0.479

High

897152

NUDC
Nuclear migration protein nudC

1

4

High-throughput

0.479

High

897154

SGT1
Protein SGT1 homolog

1

9

High-throughput

0.479

High

897155

C170B
Centrosomal protein of 170 kDa protein B

1

9

High-throughput

0.479

High

159041

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

0

High-throughput

0.458

High

354398

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

868106

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

897026

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.458

High

897040

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

897093

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

0

High-throughput

0.458

High

897095

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.458

High

897100

GLMN
Glomulin

1

0

High-throughput

0.458

High

897110

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.458

High

897115

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

897128

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

897136

COMD8
COMM domain-containing protein 8

1

0

High-throughput

0.458

High

897070

PKHA7
Pleckstrin homology domain-containing family A member 7

1

15

High-throughput

0.445

High

897081

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

3

High-throughput

0.445

High

897105

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

9

High-throughput

0.445

High

897107

CK5P2
CDK5 regulatory subunit-associated protein 2

1

20

High-throughput

0.445

High

897126

LN28A
Protein lin-28 homolog A

1

4

High-throughput

0.445

High

100644

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

329574

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

552393

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

650841

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.437

High

720125

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

897042

TIF1B
Transcription intermediary factor 1-beta

1

12

High-throughput

0.437

High

897077

MEPCE
7SK snRNA methylphosphate capping enzyme

1

7

High-throughput

0.437

High

897106

CIC
Protein capicua homolog

1

8

High-throughput

0.437

High

89957

D6R9G5
Kelch like family member 2

1

12

High-throughput

0.407

High

239894

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

4

High-throughput

0.407

High

321034

PTBP3
Polypyrimidine tract-binding protein 3

1

1

High-throughput

0.407

High

401742

JUN
Transcription factor Jun

1

4

High-throughput

0.407

High

897087

MOT11
Monocarboxylate transporter 11

1

1

High-throughput

0.407

High

897098

ESR2
Estrogen receptor beta

1

11

High-throughput

0.407

High

831167

CEBPA
CCAAT/enhancer-binding protein alpha

1

3

High-throughput

0.373

High

230329

ZC3H1
Zinc finger C3H1 domain-containing protein

1

0

High-throughput

0.279

Low

452710

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

897102

KBP
KIF-binding protein

1

0

High-throughput

0.249

Low

897131

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.249

Low

897142

TOM7
Mitochondrial import receptor subunit TOM7 homolog

1

0

High-throughput

0.249

Low

897143

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024