HitPredict

Interactor 1: E41L2 (O43491)
Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G)
Gene: EPB41L2

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30442766, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1005 Hs			1 189
+	Hs
		204589 E41L2_HUMAN (1-1005): 0: 850: 100.00		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		204670 E41L2_HUMAN (1-1005): 0: 850: 100.00		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		204588 E41L2_HUMAN (1-1005): 0: 850: 100.00		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		204641 E41L2_HUMAN (1-1005): 0: 850: 100.00		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		350550 E41L1_HUMAN (119-1005): 0: 582: 43.06		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1070395 E41L1_HUMAN (119-1005): 0: 582: 43.06		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		348923 E41L1_HUMAN (119-1005): 0: 582: 43.06		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349644 E41L1_HUMAN (119-1005): 0: 582: 43.06		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		914356 E41L1_HUMAN (119-1005): 0: 582: 43.06		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		895272 E41L1_HUMAN (119-1005): 0: 582: 43.06		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		350544 E41LB_HUMAN (194-913): 4.28e-149: 467: 25.55		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1070391 E41LB_HUMAN (194-913): 4.28e-149: 467: 25.55		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		350121 PTN13_HUMAN (79-990): 4.22e-135: 452: 15.70		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1020162 PTN13_HUMAN (79-990): 4.22e-135: 452: 15.70		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		349641 E41LB_HUMAN (194-913): 4.28e-149: 467: 25.55		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		350574 E41L5_HUMAN (183-830): 3.07e-140: 439: 27.33		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		348937 E41L5_HUMAN (183-830): 3.07e-140: 439: 27.33		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349662 E41L5_HUMAN (183-830): 3.07e-140: 439: 27.33		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		914374 E41L5_HUMAN (183-830): 3.07e-140: 439: 27.33		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		895282 E41L5_HUMAN (183-830): 3.07e-140: 439: 27.33		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52