Protein: ARBK1
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) (EC 2.7.11.15) (G-protein-coupled receptor kinase 2)

Gene: ARBK1, Grk2
Organism: Mus musculus
Interactions: 14
UniProt ID: Q99MK8

Gene Ontology (top 5):
GO:0001664 - G protein-coupled receptor binding
GO:0002026 - regulation of the force of heart contraction
GO:0002029 - desensitization of G protein-coupled receptor signaling pathway
GO:0003108 - negative regulation of the force of heart contraction by chemical signal
GO:0004672 - protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921105

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

1

9

Small-scale

0.618

High

1149069

BRSK2
Serine/threonine-protein kinase BRSK2

1

14

High-throughput

0.618

High

93280

E9PXB7
E3 ubiquitin-protein ligase

1

13

Small-scale

0.561

High

808371

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

13

Small-scale

0.561

High

1307867

SCNNB
Amiloride-sensitive sodium channel subunit beta

1

2

Small-scale

0.501

High

103182

G3X9H5
Huntingtin

1

6

High-throughput

0.479

High

620857

MDM2
E3 ubiquitin-protein ligase Mdm2

1

5

Small-scale

0.479

High

1111405

STING
Stimulator of interferon genes protein

1

4

High-throughput

0.479

High

1141234

PPP5
Serine/threonine-protein phosphatase 5

1

13

High-throughput

0.479

High

1164036

NEB2
Neurabin-2

1

14

Small-scale

0.479

High

1246973

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

High-throughput

0.479

High

1307865

PK3CG
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

1

4

Small-scale

0.479

High

929150

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

0

Small-scale

0.458

High

1307866

ITA2B
Integrin alpha-IIb

1

3

High-throughput

0.457

High


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Last updated: 15 Jul 2024