Protein: AKP13
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)

Gene: AKP13, AKAP13
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q12802

Gene Ontology (top 5):
GO:0005078 - MAP-kinase scaffold activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005938 - cell cortex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533822

KAP2
cAMP-dependent protein kinase type II-alpha regulatory subunit

6

6

Small-scale

0.930

High

900417

RHOA
Transforming protein RhoA

5

20

Small-scale

0.912

High

679338

KAP3
cAMP-dependent protein kinase type II-beta regulatory subunit

3

6

High-throughput

0.861

High

683302

1433B
14-3-3 protein beta/alpha

7

20

Small-scale

0.744

High

904499

1433G
14-3-3 protein gamma

6

20

High-throughput

0.737

High

926978

1433Z
14-3-3 protein zeta/delta

6

20

Small-scale

0.729

High

568642

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

6

12

Small-scale

0.726

High

1016912

KPCD1
Serine/threonine-protein kinase D1

1

11

Small-scale

0.724

High

1016941

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

High-throughput

0.691

High

981961

1433F
14-3-3 protein eta

4

20

High-throughput

0.691

High

475009

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

3

14

High-throughput

0.667

High

1016932

METH
Methionine synthase

3

1

High-throughput

0.667

High

1016920

ARHGI
Rho guanine nucleotide exchange factor 18

1

16

High-throughput

0.665

High

646842

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

1016933

RTKN
Rhotekin

1

1

Small-scale

0.647

High

566376

KPCA
Protein kinase C alpha type

1

12

Small-scale

0.618

High

623874

KPCL
Protein kinase C eta type

1

11

Small-scale

0.618

High

837608

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

16

Small-scale

0.618

High

915633

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

974725

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

16

Small-scale

0.618

High

909491

1433E
14-3-3 protein epsilon

2

8

High-throughput

0.611

High

1016935

MLP3A
Microtubule-associated proteins 1A/1B light chain 3A

1

1

Small-scale

0.586

High

346642

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.584

High

1016926

ARG28
Rho guanine nucleotide exchange factor 28

1

16

High-throughput

0.575

High

369491

ESR1
Estrogen receptor

1

20

Small-scale

0.573

High

237392

CCNT2
Cyclin-T2

2

4

High-throughput

0.571

High

427539

ANXA2
Annexin A2

2

5

High-throughput

0.571

High

1016921

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.553

High

1016938

CTNL1
Alpha-catulin

1

2

Small-scale

0.552

High

834726

RBP2
E3 SUMO-protein ligase RanBP2

1

7

High-throughput

0.541

High

254475

ROCK2
Rho-associated protein kinase 2

1

11

High-throughput

0.536

High

262258

ULK1
Serine/threonine-protein kinase ULK1

1

12

High-throughput

0.536

High

626111

APC
Adenomatous polyposis coli protein

1

8

High-throughput

0.536

High

647880

MARK3
MAP/microtubule affinity-regulating kinase 3

1

7

High-throughput

0.536

High

829261

SYHM
Histidine--tRNA ligase, mitochondrial

1

1

High-throughput

0.536

High

801106

KI67
Proliferation marker protein Ki-67

1

12

High-throughput

0.515

High

1016914

BAK
Bcl-2 homologous antagonist/killer

1

1

High-throughput

0.515

High

1016916

TKFC
Triokinase/FMN cyclase

1

0

High-throughput

0.513

High

394617

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

500413

THA
Thyroid hormone receptor alpha

1

15

Small-scale

0.501

High

659710

RXRB
Retinoic acid receptor RXR-beta

1

20

Small-scale

0.501

High

942620

SRPK2
SRSF protein kinase 2

1

18

High-throughput

0.501

High

992416

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.501

High

602832

TGM2
Protein-glutamine gamma-glutamyltransferase 2

1

0

Small-scale

0.484

High

227296

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.479

High

236756

CCNT1
Cyclin-T1

1

4

High-throughput

0.479

High

322534

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

4

High-throughput

0.479

High

379337

MYCN
N-myc proto-oncogene protein

1

10

High-throughput

0.479

High

430155

PROF1
Profilin-1

1

5

High-throughput

0.479

High

603151

PIMT
Protein-L-isoaspartate(D-aspartate) O-methyltransferase

1

1

High-throughput

0.479

High

684001

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

685673

PRDX2
Peroxiredoxin-2

1

3

High-throughput

0.479

High

737771

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

13

High-throughput

0.479

High

779313

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

1016908

MTA1
Metastasis-associated protein MTA1

1

2

High-throughput

0.479

High

1016909

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

15

High-throughput

0.479

High

1016910

CUL3
Cullin-3

1

11

High-throughput

0.479

High

1016911

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

4

High-throughput

0.479

High

1016913

ZYX
Zyxin

1

10

High-throughput

0.479

High

1016917

RN123
E3 ubiquitin-protein ligase RNF123

1

6

High-throughput

0.479

High

1016918

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.479

High

1016922

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1016923

TAXB1
Tax1-binding protein 1

1

19

High-throughput

0.479

High

1016924

DDX42
ATP-dependent RNA helicase DDX42

1

1

High-throughput

0.479

High

1016925

SRRM1
Serine/arginine repetitive matrix protein 1

1

12

High-throughput

0.479

High

1016927

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1016928

LNX1
E3 ubiquitin-protein ligase LNX

1

16

Small-scale

0.479

High

1016929

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1016930

FBXW7
F-box/WD repeat-containing protein 7

1

10

High-throughput

0.479

High

1016939

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

1016940

FBW1B
F-box/WD repeat-containing protein 11

1

11

High-throughput

0.479

High

214914

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

High-throughput

0.458

High

929193

RS21
Small ribosomal subunit protein eS21

1

0

High-throughput

0.458

High

1016936

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

371408

ANGI
Angiogenin

1

1

High-throughput

0.445

High

1016934

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

1016937

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

329684

AGR2
Anterior gradient protein 2 homolog

1

4

High-throughput

0.437

High

1016919

LRC31
Leucine-rich repeat-containing protein 31

1

4

High-throughput

0.437

High

239966

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

2

High-throughput

0.407

High

1016915

INSY1
Inhibitory synaptic factor 1

1

0

High-throughput

0.279

Low

1016931

GALM
Galactose mutarotase

1

0

High-throughput

0.279

Low

100709

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024