Protein: WDR74
WD repeat-containing protein 74 (NOP seven-associated protein 1)

Gene: WDR74
Organism: Homo sapiens
Interactions: 93
UniProt ID: Q6RFH5

Gene Ontology (top 5):
GO:0001825 - blastocyst formation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0006364 - rRNA processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

782042

RGS2
Regulator of G-protein signaling 2

2

4

High-throughput

0.801

High

913590

RL7A
Large ribosomal subunit protein eL8

1

11

High-throughput

0.691

High

921881

RL30
Large ribosomal subunit protein eL30

1

4

High-throughput

0.691

High

1164129

ZC3H3
Zinc finger CCCH domain-containing protein 3

1

1

High-throughput

0.691

High

1164149

PDCL3
Phosducin-like protein 3

1

4

High-throughput

0.691

High

957986

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

2

10

High-throughput

0.659

High

1164152

ARHG4
Rho guanine nucleotide exchange factor 4

2

8

High-throughput

0.659

High

1164139

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

0

High-throughput

0.656

High

347103

MYC
Myc proto-oncogene protein

3

20

High-throughput

0.640

High

1164147

MAK16
Protein MAK16 homolog

2

4

High-throughput

0.628

High

236947

BUB1B
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

1

12

High-throughput

0.618

High

1016131

ARHG5
Rho guanine nucleotide exchange factor 5

1

13

High-throughput

0.618

High

1048862

BOP1
Ribosome biogenesis protein BOP1

1

20

Small-scale

0.618

High

1164151

ANLN
Anillin

1

3

High-throughput

0.618

High

1164155

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

10

High-throughput

0.618

High

1164127

CCNJL
Cyclin-J-like protein

2

9

High-throughput

0.611

High

1164159

CARD8
Caspase recruitment domain-containing protein 8

2

0

High-throughput

0.585

High

1146526

A16L1
Autophagy-related protein 16-1

1

18

High-throughput

0.553

High

1164141

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.549

High

133533

NOP56
Nucleolar protein 56

1

9

High-throughput

0.536

High

180351

MAGB2
Melanoma-associated antigen B2

1

9

High-throughput

0.536

High

269775

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.536

High

271344

NPM3
Nucleoplasmin-3

1

8

High-throughput

0.536

High

400958

RLA0
Large ribosomal subunit protein uL10

1

9

High-throughput

0.536

High

418380

NPM
Nucleophosmin

1

8

High-throughput

0.536

High

445445

RSSA
Small ribosomal subunit protein uS2

1

4

High-throughput

0.536

High

489110

H14
Histone H1.4

1

12

High-throughput

0.536

High

557157

PGFRA
Platelet-derived growth factor receptor alpha

1

12

High-throughput

0.536

High

577998

RL17
Large ribosomal subunit protein uL22

1

6

High-throughput

0.536

High

642409

RL13
Large ribosomal subunit protein eL13

1

3

High-throughput

0.536

High

736531

RL4
Large ribosomal subunit protein uL4

1

7

High-throughput

0.536

High

739748

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

773416

RL13A
Large ribosomal subunit protein uL13

1

9

High-throughput

0.536

High

790439

RL35
Large ribosomal subunit protein uL29

1

3

High-throughput

0.536

High

801207

KI67
Proliferation marker protein Ki-67

1

16

High-throughput

0.536

High

923073

RL11
Large ribosomal subunit protein uL5

1

5

High-throughput

0.536

High

951610

RL19
Large ribosomal subunit protein eL19

1

3

High-throughput

0.536

High

971228

H11
Histone H1.1

1

12

High-throughput

0.536

High

1028702

SRSF5
Serine/arginine-rich splicing factor 5

1

19

High-throughput

0.536

High

1028965

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

1081998

PKN2
Serine/threonine-protein kinase N2

1

9

High-throughput

0.536

High

1120375

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.536

High

1164135

EFMT3
EEF1A lysine methyltransferase 3

1

3

High-throughput

0.536

High

1164137

HDA11
Histone deacetylase 11

1

20

High-throughput

0.536

High

1164143

NPAS1
Neuronal PAS domain-containing protein 1

1

6

High-throughput

0.536

High

1164145

RBM4B
RNA-binding protein 4B

1

16

High-throughput

0.536

High

1164146

MBB1A
Myb-binding protein 1A

1

5

High-throughput

0.536

High

1164150

RPF1
Ribosome production factor 1

1

4

High-throughput

0.536

High

1164153

LYAR
Cell growth-regulating nucleolar protein

1

3

High-throughput

0.536

High

1164156

IBTK
Inhibitor of Bruton tyrosine kinase

1

11

High-throughput

0.536

High

1164158

SRPK3
SRSF protein kinase 3

1

20

High-throughput

0.536

High

1164128

ARHGJ
Rho guanine nucleotide exchange factor 19

2

12

High-throughput

0.521

High

1164154

RHG23
Rho GTPase-activating protein 23

2

4

High-throughput

0.521

High

245703

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.513

High

1045257

THOC5
THO complex subunit 5 homolog

1

0

High-throughput

0.513

High

1164133

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1164138

NEIL1
Endonuclease 8-like 1

1

0

High-throughput

0.513

High

942357

DLG4
Disks large homolog 4

1

3

High-throughput

0.494

High

276249

CIB2
Calcium and integrin-binding family member 2

1

2

High-throughput

0.489

High

806568

RL28
Large ribosomal subunit protein eL28

1

2

High-throughput

0.489

High

821274

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.489

High

826726

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.489

High

943303

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.489

High

1164130

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

1

High-throughput

0.489

High

1164142

VPS35
Vacuolar protein sorting-associated protein 35

1

1

High-throughput

0.489

High

1164144

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.489

High

329109

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.486

High

162894

XPO1
Exportin-1

1

15

High-throughput

0.479

High

258078

DNJB6
DnaJ homolog subfamily B member 6

1

13

High-throughput

0.479

High

318649

EYA4
Eyes absent homolog 4

1

17

High-throughput

0.479

High

374411

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

6

High-throughput

0.479

High

379524

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

760131

RL3
Large ribosomal subunit protein uL3

1

8

High-throughput

0.479

High

779619

CCNF
Cyclin-F

1

10

High-throughput

0.479

High

824122

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

16

High-throughput

0.479

High

941063

RNF4
E3 ubiquitin-protein ligase RNF4

1

6

High-throughput

0.479

High

958205

RBM3
RNA-binding protein 3

1

16

Small-scale

0.479

High

974592

MECOM
Histone-lysine N-methyltransferase MECOM

1

3

High-throughput

0.479

High

1066282

KIF14
Kinesin-like protein KIF14

1

10

High-throughput

0.479

High

1085782

IF16
Gamma-interferon-inducible protein 16

1

6

High-throughput

0.479

High

1164132

DNJC9
DnaJ homolog subfamily C member 9

1

16

High-throughput

0.479

High

1164134

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

1164160

3BP1
SH3 domain-binding protein 1

1

5

High-throughput

0.479

High

1164131

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1164136

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1057513

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

10

High-throughput

0.445

High

100871

APRIO
Alternative prion protein

1

3

High-throughput

0.437

High

322775

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.437

High

1164148

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1164157

HECD1
E3 ubiquitin-protein ligase HECTD1

1

15

High-throughput

0.437

High

831439

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.408

High

1054835

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1164140

CC140
Coiled-coil domain-containing protein 140

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024