HitPredict

Interactor 1: SIAH2 (O43255)
E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2)
Gene: SIAH2

Interactor 2: SIAH2 (O43255)
E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (hSiah2)
Gene: SIAH2

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 26160177, 16899216, 23695783, 23891150
Identification Methods enzymatic study, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Sina~Sina
Common GO terms GO:0003714 - transcription corepressor activity
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005769 - early endosome
and 21 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 324
Hs

1 324
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024