Protein: DOC11
Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2)

Gene: DOC11, DOCK11
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q5JSL3

Gene Ontology (top 5):
GO:0001782 - B cell homeostasis
GO:0002315 - marginal zone B cell differentiation
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0007264 - small GTPase-mediated signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1127530

DOCK9
Dedicator of cytokinesis protein 9

3

12

High-throughput

0.817

High

1127521

RHG22
Rho GTPase-activating protein 22

2

6

High-throughput

0.811

High

683403

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.722

High

904658

1433G
14-3-3 protein gamma

4

20

High-throughput

0.699

High

982087

1433F
14-3-3 protein eta

4

20

High-throughput

0.699

High

646953

1433T
14-3-3 protein theta

4

20

High-throughput

0.697

High

927120

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.697

High

350225

RASK
GTPase KRas

1

14

High-throughput

0.618

High

545421

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564557

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

892410

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

894099

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

915729

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

925332

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

1127534

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

670886

GFRP
GTP cyclohydrolase 1 feedback regulatory protein

2

0

High-throughput

0.602

High

1127533

PAAT
ATPase PAAT

2

1

High-throughput

0.574

High

1127531

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.553

High

1127532

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.553

High

909638

1433E
14-3-3 protein epsilon

1

5

High-throughput

0.536

High

999595

AHNK
Neuroblast differentiation-associated protein AHNAK

1

0

High-throughput

0.493

High

322721

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.479

High

684083

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

740539

PPARG
Peroxisome proliferator-activated receptor gamma

1

3

High-throughput

0.479

High

779542

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

846562

DUS3
Dual specificity protein phosphatase 3

1

2

High-throughput

0.479

High

1022678

RHG05
Rho GTPase-activating protein 5

1

5

High-throughput

0.479

High

1127518

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.479

High

1127525

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

1127526

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1127535

RCC2
Protein RCC2

1

2

Small-scale

0.479

High

963834

SET
Protein SET

1

0

High-throughput

0.458

High

1025030

REST
RE1-silencing transcription factor

1

0

High-throughput

0.458

High

791636

HD
Huntingtin

1

2

High-throughput

0.457

High

108781

H0Y572
Dedicator of cytokinesis 9

1

3

High-throughput

0.445

High

1127528

CYGB
Cytoglobin

1

1

Small-scale

0.445

High

1127519

MOB3C
MOB kinase activator 3C

1

11

High-throughput

0.437

High

1127520

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

1127522

MOB3B
MOB kinase activator 3B

1

11

High-throughput

0.437

High

1127523

KTN1
Kinectin

1

3

High-throughput

0.437

High

1127524

SIR6
NAD-dependent protein deacylase sirtuin-6

1

2

High-throughput

0.437

High

1127527

CE192
Centrosomal protein of 192 kDa

1

0

High-throughput

0.426

High

207725

DENR
Density-regulated protein

2

0

High-throughput

0.328

High

433061

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

2

0

High-throughput

0.328

High

1127529

GORS1
Golgi reassembly-stacking protein 1

2

0

High-throughput

0.328

High

316656

ACSL3
Fatty acid CoA ligase Acsl3

1

0

High-throughput

0.269

Low

764389

FEN1
Flap endonuclease 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024