Protein: CPT1A
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1-L) (EC 2.3.1.21) (Carnitine O-palmitoyltransferase I, liver isoform) (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) (Succinyltransferase CPT1A) (EC 2.3.1.-)

Gene: CPT1A
Organism: Homo sapiens
Interactions: 110
UniProt ID: P50416

Gene Ontology (top 5):
GO:0001666 - response to hypoxia
GO:0001676 - long-chain fatty acid metabolic process
GO:0004095 - carnitine O-palmitoyltransferase activity
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

226880

PRKN
E3 ubiquitin-protein ligase parkin

2

1

Small-scale

0.584

High

839306

RAC1
Ras-related C3 botulinum toxin substrate 1

2

3

High-throughput

0.571

High

839308

KPCZ
Protein kinase C zeta type

2

1

High-throughput

0.571

High

839311

CLN3
Battenin

2

0

Small-scale

0.559

High

839357

HDAC6
Histone deacetylase 6

2

1

High-throughput

0.558

High

584222

ELK1
ETS domain-containing protein Elk-1

2

0

High-throughput

0.547

High

118950

KCNK1
Potassium channel subfamily K member 1

1

1

High-throughput

0.536

High

163773

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

1

High-throughput

0.536

High

171960

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.536

High

355023

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

1

High-throughput

0.536

High

530854

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

839358

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.533

High

783952

KPCI
Protein kinase C iota type

2

1

High-throughput

0.521

High

839309

PAK1
Serine/threonine-protein kinase PAK 1

2

2

High-throughput

0.521

High

124597

CLIC1
Chloride intracellular channel protein 1

1

0

High-throughput

0.518

High

499629

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.515

High

440419

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

0

High-throughput

0.513

High

488166

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

0

High-throughput

0.513

High

505364

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

0

High-throughput

0.513

High

580344

TSN8
Tetraspanin-8

1

0

High-throughput

0.513

High

677902

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

0

High-throughput

0.513

High

792750

EAA3
Excitatory amino acid transporter 3

1

0

High-throughput

0.513

High

839302

RAB7A
Ras-related protein Rab-7a

1

0

High-throughput

0.513

High

839314

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.513

High

839325

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.513

High

839327

INLR1
Interferon lambda receptor 1

1

0

High-throughput

0.513

High

839330

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.513

High

839336

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

839341

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.513

High

839346

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.513

High

839349

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

839354

S39A9
Zinc transporter ZIP9

1

0

High-throughput

0.513

High

839359

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.513

High

410553

CD1A
T-cell surface glycoprotein CD1a

1

1

High-throughput

0.489

High

540285

GPIX
Platelet glycoprotein IX

1

1

High-throughput

0.489

High

839339

HDA11
Histone deacetylase 11

1

2

High-throughput

0.489

High

839361

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.489

High

839337

ESR2
Estrogen receptor beta

1

1

High-throughput

0.484

High

611399

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

3

High-throughput

0.481

High

475493

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

130465

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

1

High-throughput

0.479

High

258418

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

1

High-throughput

0.479

High

319765

HERC2
E3 ubiquitin-protein ligase HERC2

1

1

High-throughput

0.479

High

384500

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.479

High

839303

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.479

High

839313

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

501839

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.460

High

528161

CY24A
Cytochrome b-245 light chain

1

0

High-throughput

0.460

High

167867

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

334164

LDHA
L-lactate dehydrogenase A chain

1

0

Small-scale

0.458

High

351994

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

373891

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

386326

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

390778

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

433650

LYN
Tyrosine-protein kinase Lyn

1

0

Small-scale

0.458

High

724415

PCKGC
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]

1

0

Small-scale

0.458

High

807638

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

839301

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

839305

H4
Histone H4

1

0

High-throughput

0.458

High

839312

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

839316

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

839326

TAXB1
Tax1-binding protein 1

1

0

High-throughput

0.458

High

839329

PLD6
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.458

High

839332

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

839355

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

436209

RHOC
Rho-related GTP-binding protein RhoC

1

3

High-throughput

0.437

High

450773

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.437

High

650689

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

839304

RHOA
Transforming protein RhoA

1

3

High-throughput

0.437

High

839315

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.437

High

839322

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

839324

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.437

High

839328

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.437

High

839351

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.437

High

111534

SIM22
Small integral membrane protein 22

1

0

Small-scale

0.426

High

394351

A4
Amyloid-beta precursor protein

1

0

Small-scale

0.426

High

577437

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

2

0

High-throughput

0.328

High

839321

TBCD9
TBC1 domain family member 9

2

0

High-throughput

0.328

High

839334

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

0

High-throughput

0.282

High

245220

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

613962

TBG1
Tubulin gamma-1 chain

1

0

High-throughput

0.279

Low

795937

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.279

Low

839307

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.279

Low

839310

KLRD1
Natural killer cells antigen CD94

1

0

High-throughput

0.279

Low

839319

T184A
Transmembrane protein 184A

1

0

High-throughput

0.279

Low

839335

ITLN1
Intelectin-1

1

0

High-throughput

0.279

Low

839340

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

839345

TMM59
Transmembrane protein 59

1

0

High-throughput

0.279

Low

839348

ADAM7
Disintegrin and metalloproteinase domain-containing protein 7

1

0

High-throughput

0.279

Low

839360

PCDGM
Protocadherin gamma-C5

1

0

High-throughput

0.279

Low

839362

NPTN
Neuroplastin

1

0

High-throughput

0.279

Low

839352

NPDC1
Neural proliferation differentiation and control protein 1

1

0

High-throughput

0.251

Low

196280

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

205180

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

329503

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

839317

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.249

Low

839318

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

839323

UBP50
Ubiquitin carboxyl-terminal hydrolase 50

1

0

Small-scale

0.249

Low

839333

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.249

Low

839338

OPTN
Optineurin

1

0

High-throughput

0.249

Low

839343

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.249

Low

839344

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

839347

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.249

Low

839350

Q9H4D1
Protein kinase

1

0

High-throughput

0.249

Low

839353

FBX6
F-box only protein 6

1

0

High-throughput

0.249

Low

839356

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

353916

IGHM
Immunoglobulin heavy constant mu

1

0

High-throughput

0.232

Low

839320

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

0

High-throughput

0.232

Low

839331

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low

839342

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024